Protein Alignment Mmp1 and mmp16

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_012820122.1
• Gene: mmp16 / 548746
• XenbaseID: XB-GENE-1007177
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 621
• Identity: 209/621 - (33%)
• Similarity: 296/621 - (47%)
• Gaps: 101/621 - (16%)

  Fly     4 CQSSVFIVVGTLFSIMAAAQSAPVSTTTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEF 68
            |:|...||:..|:.:.|....   .....||::|.::||||.:  :|..|.|....|..|||...
 Frog    15 CRSVGLIVLSLLWIVCAVGAG---EQGFSAEMWLQKYGYLPPT--DPRMSVLRSAETMQSAIAAM 74

  Fly    69 QSFAGLNITGELDAE-----TMKLMSLPRCGVRDRVG---TGDSRSKRYALQGSRWRVKNLTYKI 125
            |.|.|:|.||::|..     |:..|..|||||||:.|   ..:.|.|||||.|.:|..|::||.|
 Frog    75 QQFYGINATGKIDKNTIDEITLSWMKKPRCGVRDQAGPISRFNVRRKRYALTGQKWHHKHITYSI 139

  Fly   126 SKYPKRLKRVDVDAEIGRAFAVWSEDTDLTF-------TRKTSGPVHIEIKFVESEHGDGDAFDG 183
            .....::...:....|.|||.||...|.|||       .......|.|.|.|....|||...|||
 Frog   140 KNVTPKVGDSETRKAIRRAFDVWQNVTPLTFEEVPYCELENGKRDVDITIIFASGFHGDSSPFDG 204

  Fly   184 QGGTLAHAFF--PVFGGDAHFDDAELWTIGSPR--GTNLFQVAAHEFGHSLGLSHSDQSSALMAP 244
            :||.||||:|  |..|||.|||..|.||:|:|.  |.:||.||.||.||:|||.||:..:|:|||
 Frog   205 EGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAP 269

  Fly   245 FYRGFE-PVFKLDEDDKAAIQSLYGRKTNQLRPTN-------------VYPATTQRPYSPPKVPL 295
            ||:..| ..|||..||...||.:||.......||.             |.|....|...||:.|.
 Frog   270 FYQYMETDNFKLPTDDLQGIQKIYGPPEKAPAPTKPLPTVPPHRSVPPVDPRKNDRQPKPPRPPT 334

  Fly   296 DD---------SICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPGNI 351
            .|         :|| |...:|| ...:.|.:.||...::::..:.|.:|||..|:..|.|||..|
 Frog   335 GDKPSYPGAKPNIC-DGNFNTL-AILRREMFVFKDQWFWRVRNNKVMDGYPMQITYFWRGLPPGI 397

  Fly   352 DAAFTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDH-LDAAMVWGGNGKIYFFKGS 415
            ||.:..:.|...||||.:||.::...:...||.::.....|||.| :|.|:.|...||.|||||.
 Frog   398 DAVYENREGNFVFFKGNKYWIFKDTTLQPGYPYDLMHLGHGIPPHGIDTAVWWEDVGKTYFFKGD 462

  Fly   416 KFWRFDPAKRPPVKASYPKPISNWEGVPNNLDAA-LKYTNGYTYFFKGDKYYRFHDARFAVDSAT 479
            ::||::...| .:...|||.|:.|:|:|.:...| :...||:|||:||.:|::|.:....|:
 Frog   463 RYWRYNEEMR-VMDPGYPKLITVWKGIPESPQGAFVDKENGFTYFYKGKEYWKFQNLNLRVE--- 523

  Fly   480 PPFPRPTAHWWFGCKNTPSSTGNIVEGS-DNEFEQHSMIPHADDGNGDDFDAAVGDHQSNDEPIV 543
            |.:||.....:.||           :|| |.:.|:.|  |.      ||.|..:
 Frog   524 PGYPRSILKDFMGC-----------DGSTDGDKERTS--PQ------DDVDIVI----------- 558

  Fly   544 PEVAERTGNGAMSQSKLTSSSAVSTVITTILMCLVS 579
                           ||.::::....|..::.|:::
 Frog   559 ---------------KLDNTASTVKAIAIVIPCILA 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	22/60 (37%)
		Peptidase_M10	115..268	CDD:425668	72/164 (44%)
		HX	298..493	CDD:238046	67/196 (34%)
mmp16	XP_012820122.1	PG_binding_1	41..92	CDD:460223	21/52 (40%)
		Peptidase_M10	129..294	CDD:425668	72/164 (44%)
		PHA03247	<276..356	CDD:223021	23/81 (28%)
		HX	345..537	CDD:238046	67/197 (34%)
		DUF3377	542..612	CDD:463374	11/72 (15%)