Protein Alignment Mmp1 and Hpx

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_059067.2
• Gene: Hpx / 15458
• MGIID: 105112
• Length: 460
• Species: Mus musculus
• Alignment Length: 250
• Identity: 62/250 - (24%)
• Similarity: 98/250 - (39%)
• Gaps: 70/250 - (28%)

  Fly   290 PPKVPLD-----------------------------DSICK-DSKVDTLFNSAQGETYAFKGDKY 324
            ||:.|||                             .|.|. |..:..|.:..:|.||||.|..|
Mouse   216 PPRYPLDARDYFVSCPGRGHGRPRNGTAHGNSTHPMHSRCSPDPGLTALLSDHRGATYAFTGSHY 280

  Fly   325 YKLTTDSVEEGYPQL-ISKGWPGLPGNIDAAFTYKNGKTYFFKGTQYWRY---QGRQMDGVYPKE 385
            ::|  ||..:|:... |:..||..|..:||||:: :.|.|..:|||.:.:   .|..:...|||.
Mouse   281 WRL--DSSRDGWHSWPIAHHWPQGPSTVDAAFSW-DDKVYLIQGTQVYVFLTKGGNNLVSGYPKR 342

  Fly   386 ISEGFTGIP----DHLDAAMVWGGNGKIYFFKGSKFWRFD---PAKRPPVKASYPKPISNWEGVP 443
            :.:.....|    :.:|||....|:.::|...|.:.|..|   .|:....:.|:|.
Mouse   343 LEKELGSPPGISLETIDAAFSCPGSSRLYVSSGRRLWWLDLKSGAQATWTEVSWPH--------- 398

  Fly   444 NNLDAALKY----------TNGYT-YFFKGDKYYRFHDARFAVD--SATPPFPRP 485
            ..:|.||..          :||.: ||..|...|.:.    ::|  :|....|:|
Mouse   399 EKVDGALCLDKSLGPNTCSSNGSSLYFIHGPNLYCYS----SIDKLNAAKSLPQP 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223
		Peptidase_M10	115..268	CDD:425668
		HX	298..493	CDD:238046	56/212 (26%)
Hpx	NP_059067.2	HX	47..230	CDD:238046	5/13 (38%)
		Hemopexin 1	53..93
		Hemopexin 2	94..138
		Hemopexin 3	139..183
		Hemopexin 4	184..230		5/13 (38%)
		HX	253..458	CDD:238046	56/212 (26%)
		Hemopexin 5	257..302		16/46 (35%)
		Hemopexin 6	303..350		14/47 (30%)
		Hemopexin 7	355..394		9/38 (24%)
		Hemopexin 8	398..448		11/62 (18%)