Protein Alignment Mmp1 and mmp15b

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_021323108.1
• Gene: mmp15b / 100332426
• ZFINID: ZDB-GENE-070817-6
• Length: 655
• Species: Danio rerio
• Alignment Length: 626
• Identity: 212/626 - (33%)
• Similarity: 307/626 - (49%)
• Gaps: 81/626 - (12%)

  Fly    15 LFSIMAAAQSAPV--STTTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNIT 77
            :||::.....|..  ..|...|.:|..:||||.::|.  .|.:...:...:||.:.|.|.||.||
Zfish    19 VFSLLLLLMGARTFGDETFSGESWLRMYGYLPQASRQ--MSTMRSAQILSNAISDMQRFYGLEIT 81

  Fly    78 GELDAETMKLMSLPRCGVRDRVGT---GDSRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVDA 139
            ||:|..|::.|..|||||.|:.|.   .:.|.|||||.|.:|...::|:.|..|..::...:...
Zfish    82 GEMDPGTIEAMKRPRCGVPDKFGAQIKTNVRRKRYALTGHKWDKTHITFSIQNYTPKIGEYNSYE 146

  Fly   140 EIGRAFAVWSEDTDLTFTRKTSGPVH-----------IEIKFVESEHGDGDAFDGQGGTLAHAFF 193
            .|.|||.||.:.|.|||...   |.|           |.|.|....|||...|||:||.||||:|
Zfish   147 AIRRAFRVWEKVTPLTFDEI---PFHEVKYGRRKEPDIMIFFASGFHGDSSPFDGEGGFLAHAYF 208

  Fly   194 --PVFGGDAHFDDAELWTIGSP--RGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPV-F 253
              |..|||.|||..|.|||||.  :|.:||.||.||.||:|||.||:...|:|||||:..:.. |
Zfish   209 PGPGMGGDTHFDSDEPWTIGSQNLQGNDLFLVAVHELGHALGLEHSNNPLAIMAPFYQWMDTENF 273

  Fly   254 KLDEDDKAAIQSLYGRKTNQLRPTNVYPATTQR------------PYSPPKVP------------ 294
            :|.|||...:|.:||..::.  ||...|..|.|            |.|||..|
Zfish   274 ELPEDDLRGVQQIYGPPSSS--PTQALPTVTPRRPAHPDPRAPNPPKSPPGAPPRRPDKPRTTDR 336

  Fly   295 ---LDDSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPGNIDAAFT 356
               ...:|| :...||: ...:||.:.|||..::::..:.|.:.||..|...|.||||:||||:.
Zfish   337 PDHYGPNIC-EGNFDTV-TMLRGEMFVFKGRWFWRVRRNRVLDNYPMPIGHFWRGLPGDIDAAYE 399

  Fly   357 YKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIP-DHLDAAMVWGGNGKIYFFKGSKFWRF 420
            ..:|:..||||:|||.::...::..||:|:.:....|| |.:|.|:.|..:|..|||||..:|||
Zfish   400 RHDGRFVFFKGSQYWLFREANLESGYPQELMDYGRDIPYDKIDTAIWWEPSGFTYFFKGDWYWRF 464

  Fly   421 DPAKRPPVKASYPKPISNW-EGVPNNLDAALKYTNG-YTYFFKGDKYYRFHDARFAVDSATPPFP 483
            :...| .....||||||.| ..||::...|....:| ||||:||.||::|.:.|.   ::.|.:|
Zfish   465 NEQDR-AADQDYPKPISVWGTSVPSSPKGAFLSDDGAYTYFYKGAKYWKFDNHRM---TSEPGYP 525

  Fly   484 RPTAHWWFGCKNTPSSTGNIVEGSDNEFEQHSMIPHADDGNGD-------DFDAAVGDHQSNDEP 541
            :.....:.||      ..::....|.:.:|....|.....|.|       |.|.......:||..
Zfish   526 KSILRDFMGC------NVDLDPDRDTDVDQGRKWPDRPPFNPDAGRDKDKDKDKDKERDNTNDAD 584

  Fly   542 IVPEVAERTGNG----AMSQSKLTSSSAVSTVITTILMCLV 578
            ...|..|:|...    .:.:::.|.:..:.||...:::|::
Zfish   585 SKEETEEKTNEVDVVLKIDETERTMNIIMVTVPLVLVLCIL 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	20/55 (36%)
		Peptidase_M10	115..268	CDD:425668	71/168 (42%)
		HX	298..493	CDD:238046	72/197 (37%)
mmp15b	XP_021323108.1	PG_binding_1	42..92	CDD:460223	19/51 (37%)
		Peptidase_M10	122..288	CDD:425668	71/168 (42%)
		HX	342..535	CDD:238046	72/198 (36%)
		DUF3377	596..655	CDD:463374	4/30 (13%)