Protein Alignment Mmp1 and mmp19

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_031753026.1
• Gene: mmp19 / 100127631
• XenbaseID: XB-GENE-5932824
• Length: 476
• Species: Xenopus tropicalis
• Alignment Length: 494
• Identity: 193/494 - (39%)
• Similarity: 264/494 - (53%)
• Gaps: 36/494 - (7%)

  Fly     8 VFIVVGTLFSIMAAAQSAPVSTTTQAEIYLSQFGYLPASARNPASSGLHD--QRTWVSAIEEFQS 70
            :|:::|||...:.|....| |:..:|:.||.|||||    :.|..|...|  ......|:..||.
 Frog     7 LFLLLGTLPFFVYAMHIEP-SSGEEAKRYLQQFGYL----QKPLESDTEDFSSEEVQEALRIFQL 66

  Fly    71 FAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYKISKYPKRLKRV 135
            ...|..||.||.:|:..|..|||||.|..   :.::.||.|.| |||.|||||:|..|...:...
 Frog    67 STHLPGTGVLDEDTIDKMRQPRCGVEDPF---NQKTLRYLLLG-RWRKKNLTYRIYNYTPDMSLA 127

  Fly   136 DVDAEIGRAFAVWSEDTDLTFTRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDA 200
            ...:.|...|..||:.|.|||...|.|...|.|.|....:|....|||.|..||||..|.. |..
 Frog   128 AARSAILAGFKYWSDVTPLTFKEVTRGRADIRISFHRRGNGCSRPFDGPGKVLAHADIPEL-GTV 191

  Fly   201 HFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQS 265
            |||:.||||.|:..|.||..:||||.||:|||.||...||||||.|.|::|.|:|.:||...||:
 Frog   192 HFDEDELWTEGTYEGVNLRIIAAHELGHALGLGHSRFRSALMAPIYFGYKPNFRLHDDDVKGIQA 256

  Fly   266 LYGRKTNQLRPTNVYPATTQRP---YSPPKVPLDDSICKDSKVDTLFNSAQGETYAFKGDKYYKL 327
            |||:| :::....|  .||:.|   ..|....|....|.|: :|.:.....|:|||||||..:.:
 Frog   257 LYGKK-DKIEEEEV--VTTEEPAISAEPTPTSLTPDPCNDN-LDAIILGPYGKTYAFKGDYVWTI 317

  Fly   328 TTDSVEEGYPQL-ISKGWPGLPGNIDAA-FTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGF 390
            |...:.   |.: |...|.||||||||| .:.:..:||||||.:.|.|...:::..|||.|
 Frog   318 TDFGIS---PLIRIQSLWKGLPGNIDAAVHSPRTQRTYFFKGDKLWVYTNFKLNPGYPKLI---- 375

  Fly   391 TGIPDHLDAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISN-WEGVPNNLDAALKYTN 454
            |.:|.:::||:.|..|.||:.|||..:|::|......:.:   |.||: :.|:|:.||||:.:.|
 Frog   376 TRVPPNINAALYWEVNKKIFLFKGDGYWQWDELGWSNLSS---KKISSLFTGIPSQLDAAVTWKN 437

  Fly   455 GYTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGC 493
            |..||||||||:|. :.:..|:..   :|...|..|..|
 Frog   438 GKIYFFKGDKYWRV-NKQLRVERG---YPLSKAERWMQC 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	20/57 (35%)
		Peptidase_M10	115..268	CDD:425668	72/152 (47%)
		HX	298..493	CDD:238046	73/197 (37%)
mmp19	XP_031753026.1	PG_binding_1	29..84	CDD:460223	20/58 (34%)
		ZnMc_MMP	107..259	CDD:239805	72/152 (47%)
		HX	288..472	CDD:238046	73/198 (37%)