Protein Alignment Mmp1 and mmp25a

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001427818.1
• Gene: mmp25a / 100001739
• ZFINID: ZDB-GENE-070820-22
• Length: 576
• Species: Danio rerio
• Alignment Length: 592
• Identity: 178/592 - (30%)
• Similarity: 267/592 - (45%)
• Gaps: 101/592 - (17%)

  Fly    36 YLSQFGYLPASARNPAS--SGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDR 98
            :|.::|||    ::|.:  .||..:.:...|:.:.|.|||:..||.||.:|:::|..|||.:.|.
Zfish    33 WLIRYGYL----QSPDTLIGGLQTKESIEEAVRKMQRFAGIEETGNLDQKTLEMMGRPRCSLPDT 93

  Fly    99 VGTGD-------------SRSKRYALQGSRWRVKNLTYKISKYP-----KRLKRVDVDAEIGRAF 145
            :...:             .:.|||.|...||...::|:.:..:|     ..|....|...:|.|.
Zfish    94 ISFEELLKRNRRGKNKVMMKKKRYTLPKMRWDKTDITWSMQDFPPPSVSPALNPGLVRLILGNAL 158

  Fly   146 AVWSEDTDLTFTRKTSGP---VHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFG---GDAHFDD 204
            .||||:|.|.|......|   ..|.:.|....|.||..|||:||.|||||||..|   ||.|||.
Zfish   159 RVWSENTPLRFHYSPDEPSPQTDITVTFTSGYHEDGYPFDGKGGALAHAFFPGKGDLAGDTHFDA 223

  Fly   205 AELWTIGS-PRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPV-----FKLDEDDKAAI 263
            .|.||.|. ...::||.||.|||||:|||.||..|.::|.|:|  |.||     :.|...|:..|
Zfish   224 EESWTYGDWSSDSDLFTVAVHEFGHALGLFHSSSSDSIMKPYY--FSPVGEMNSYSLTAVDRLGI 286

  Fly   264 QSLYGRKTNQLRPTNV-----YPATTQRPY--SPPKVPLDDSICKDSKVDTLFNSAQGETYAFKG 321
            |:|||::.|...|.:|     ||......|  .||..|.|.:.......|.:.| .:.|.:.|:|
Zfish   287 QALYGKQHNLKPPPSVAAPTTYPTQFSTTYLLHPPYYPPDSADRCQGGYDAVAN-IRAEIFFFRG 350

  Fly   322 DKYYKLT-TDSVEEGYPQLISKGWPGLP---GNIDAAFTYKNGKTYFFKGTQYWRYQGRQMDGVY 382
            ..::::. :.|:....|.||...|.|||   ..:|||:..::|...||.|.|||.::.......|
Zfish   351 QHFWRVDHSGSLLSSTPALIHSFWIGLPPDTARVDAAYERRDGHIVFFIGNQYWVFRNTMALPGY 415

  Fly   383 PKEISE-----GFTGIPDHLDAAMVWGGNGKIYFFKGSKFWRFDPA-KRPPVKASYPKPISNWEG 441
            |:::|:     ....:.:.::|..||..|||.|.|....:||||.| ....::..||||.:.| |
Zfish   416 PRQLSDWGLHTAAGQLAESVEAVFVWPHNGKTYVFSSGLYWRFDEAGGERKMEEGYPKPAAIW-G 479

  Fly   442 VPNNLDAALKYTNGYTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGCKNTPSSTGNIVEG 506
            :|::.|..:.:.:|.|||||...|:........::||:   |:..|..|..|..
Zfish   480 MPSHPDDIIAFLDGETYFFKDSNYWILQRGGLDLESAS---PKSIATDWMKCDR----------- 530

  Fly   507 SDNEFEQHSMIPHADDGNGDDFDAAVGDHQSNDEPIVPEVAERTGNGAMSQSKLTSSSAVSTVIT 571
                                        |.|...|.:|.  :|..:...:.:.:..|.:|...:|
Zfish   531 ----------------------------HVSAPTPEIPR--DRNCSCVQNVAAVMRSLSVIIYLT 565

  Fly   572 TILMCLV 578
            .|:..||
Zfish   566 NIICILV 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	17/53 (32%)
		Peptidase_M10	115..268	CDD:425668	69/169 (41%)
		HX	298..493	CDD:238046	59/204 (29%)
mmp25a	NP_001427818.1	None