Protein Alignment: Pgam5-2 and PGAM5

• Sequence 1: NP_611911.1
• Gene: Pgam5-2
• FlyBaseID: FBgn0035004
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_001164014.1
• Gene: PGAM5
• HGNCID: 28763
• Length: 289
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 116/267 (43%)
• Similarity: 144/267 (54%)
• Gaps: 49/267 (18%)

  Fly    31 EPSMLSGGAQGGKGRAIEPLASGAWRHHWDLDKP------QLQKVANGEE----------SSALR 79
            ||...:|||:.|         .|.|..:||..:|      :.:.|.:|||          :.|.|
Human    43 EPPAWAGGARPG---------PGVWDPNWDRREPLSLINVRKRNVESGEEELASKLDHYKAKATR 98

  Fly    80 HIILVRHGEY--------TRTPNGSHLTELGRRQAERTGQRLREMGLSWDHVVASTMPRAEETAM 136
            ||.|:||.:|        .||     ||.|||.|||.||.||..:||.::.:|.|:|.||.||..
Human    99 HIFLIRHSQYHVDGSLEKDRT-----LTPLGREQAELTGLRLASLGLKFNKIVHSSMTRAIETTD 158

  Fly   137 IILKQLNLDPLKMKRCT-LLPEGTPYPGDPPS---KRSARSLDLAYQRDGPRIEAAFRRYFFRAS 197
            ||.:.|   |...|..| ||.||.|...|||.   |..|    :.|..||.|||||||.|..||.
Human   159 IISRHL---PGVCKVSTDLLREGAPIEPDPPVSHWKPEA----VQYYEDGARIEAAFRNYIHRAD 216

  Fly   198 PEQEHDSYLLIVGHSNVIRYLILRALQLPPAAWTRLNLNHGSITWLTVWPSGYVTLRCLGDSGFM 262
            ..||.|||.:.:.|:|||||::.||||.||..|.||:||:||||.|.:.|:|.|.||.|||:|||
Human   217 ARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLSLNNGSITHLVIRPNGRVALRTLGDTGFM 281

  Fly   263 PVTEIT 268
            |..:||
Human   282 PPDKIT 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgam5-2	NP_611911.1	HP_PGM_like	80..245	CDD:132718	85/177 (48%)
PGAM5	NP_001164014.1	Interaction with KEAP1	77..82		2/5 (40%)
		HP_PGM_like	99..272	CDD:132718	88/185 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C152638447
eggNOG	1	0.900				E1_KOG4609
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D1112626at2759
OrthoFinder	1	1.000				FOG0005244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR20935
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R2720
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	9	8.850