Protein Alignment CG42383 and SHP1

DIOPT Version :8

• Sequence 1: NP_523847.2
• Gene: CG42383 / 37897
• FlyBaseID: FBgn0259729
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_009495.1
• Gene: SHP1 / 852222
• SGDID: S000000154
• Length: 423
• Species: Saccharomyces cerevisiae
• Alignment Length: 428
• Identity: 104/429 (24%)
• Similarity: 159/429 (37%)
• Gaps: 111/429 (26%)

  Fly     4 EQKLSTFMKRHGVREEVARQYLSSNNWSLEVASSTYESEAVSKK-----------QEPEKSSEHS 57
            ::.:..||....|...:|.||||......|..:|.|.|:...:|           ||.....|..
Yeast     6 DETIQQFMALTNVSHNIAVQYLSEFGDLNEALNSYYASQTDDQKDRREEAHWNRQQEKALKQEAF 70

  Fly    58 QANESNRDLHSL--------------LSEISRRK---------------EGDHDGYQACASD--- 90
            ..|.||:.:::.              .:|..:||               .|::..:.: .||
Yeast    71 STNSSNKAINTEHVGGLCPKPGSSQGSNEYLKRKGSTSPEPTKGSSRSGSGNNSRFMS-FSDMVR 134

  Fly    91 ---SSTDHDTP-----AGKRVNINSSTPAITN-----------------------NDSDRSL--- 121
               ...|.|.|     .|:...:..:.|:..|                       :|.|..:
Yeast   135 GQADDDDEDQPRNTFAGGETSGLEVTDPSDPNSLLKDLLEKARRGGQMGAENGFRDDEDHEMGAN 199

  Fly   122 RVWGHGNRLGSAHPINPPPRSATEDSDTEPADD---------EHTIVVLHLWSEGFSLDDGSLRL 177
            |..|.|.||||           |.|:..|..:|         |.....:..|.|||.:.||.|..
Yeast   200 RFTGRGFRLGS-----------TIDAADEVVEDNTSQSQRRPEKVTREITFWKEGFQVADGPLYR 253

  Fly   178 YALPENERFLRAILRGDFPEEMLRV---PRVQLSVQDHTNESYRHLSRK--QFMGPGRPLNSPSP 237
            |..|.|..:|..:.:|..|.::|.|   ..|:::|....:|||:..:||  .|.|.|:.|.||.|
Yeast   254 YDDPANSFYLSELNQGRAPLKLLDVQFGQEVEVNVYKKLDESYKAPTRKLGGFSGQGQRLGSPIP 318

  Fly   238 QILVVGPMP------VEAQGLQLNE-RADTTTVQLRMADGSRVAGRFNLTHNVGDLYQYARLARP 295
            .......:|      .:.|.:..|| :...|::|:|.|:|.|.....|.|..|..||::......
Yeast   319 GESSPAEVPKNETPAAQEQPMPDNEPKQGDTSIQIRYANGKREVLHCNSTDTVKFLYEHVTSNAN 383

  Fly   296 EFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVVIQ 333
            ....|:|.|..|||.:. :.:|..||..|:|.|.||:|
Yeast   384 TDPSRNFTLNYAFPIKP-ISNDETTLKDADLLNSVVVQ 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459	10/29 (34%)
		SEP	155..242	CDD:197786	30/92 (33%)
		p47_UBX	257..336	CDD:176365	26/78 (33%)
SHP1	NP_009495.1	UBA_Ubx1_like	6..41	CDD:270536	10/35 (29%)
		SEP	231..323	CDD:197786	30/92 (33%)
		p47_UBX	345..423	CDD:176365	26/78 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C39548046
eggNOG	1	0.900				E1_KOG2086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000961
OrthoInspector	1	1.000				T634655
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR23333
Phylome	1	0.910		0.857	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	7	6.800