Protein Alignment CG42383 and SHP1

DIOPT Version :10

• Sequence 1: NP_523847.2
• Gene: CG42383 / 37897
• FlyBaseID: FBgn0259729
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_009495.1
• Gene: SHP1 / 852222
• SGDID: S000000154
• Length: 423
• Species: Saccharomyces cerevisiae
• Alignment Length: 428
• Identity: 104/428 - (24%)
• Similarity: 159/428 - (37%)
• Gaps: 111/428 - (25%)

  Fly     4 EQKLSTFMKRHGVREEVARQYLSSNNWSLEVASSTYESEAVSKK-----------QEPEKSSEHS 57
            ::.:..||....|...:|.||||......|..:|.|.|:...:|           ||.....|..
Yeast     6 DETIQQFMALTNVSHNIAVQYLSEFGDLNEALNSYYASQTDDQKDRREEAHWNRQQEKALKQEAF 70

  Fly    58 QANESNRDLHSL--------------LSEISRRK---------------EGDHDGYQACASD--- 90
            ..|.||:.:::.              .:|..:||               .|::..:.: .||
Yeast    71 STNSSNKAINTEHVGGLCPKPGSSQGSNEYLKRKGSTSPEPTKGSSRSGSGNNSRFMS-FSDMVR 134

  Fly    91 ---SSTDHDTP-----AGKRVNINSSTPAITN-----------------------NDSDRSL--- 121
               ...|.|.|     .|:...:..:.|:..|                       :|.|..:
Yeast   135 GQADDDDEDQPRNTFAGGETSGLEVTDPSDPNSLLKDLLEKARRGGQMGAENGFRDDEDHEMGAN 199

  Fly   122 RVWGHGNRLGSAHPINPPPRSATEDSDTEPADD---------EHTIVVLHLWSEGFSLDDGSLRL 177
            |..|.|.||||           |.|:..|..:|         |.....:..|.|||.:.||.|..
Yeast   200 RFTGRGFRLGS-----------TIDAADEVVEDNTSQSQRRPEKVTREITFWKEGFQVADGPLYR 253

  Fly   178 YALPENERFLRAILRGDFPEEMLRV---PRVQLSVQDHTNESYRHLSRK--QFMGPGRPLNSPSP 237
            |..|.|..:|..:.:|..|.::|.|   ..|:::|....:|||:..:||  .|.|.|:.|.||.|
Yeast   254 YDDPANSFYLSELNQGRAPLKLLDVQFGQEVEVNVYKKLDESYKAPTRKLGGFSGQGQRLGSPIP 318

  Fly   238 QILVVGPMP------VEAQGLQLNE-RADTTTVQLRMADGSRVAGRFNLTHNVGDLYQYARLARP 295
            .......:|      .:.|.:..|| :...|::|:|.|:|.|.....|.|..|..||::......
Yeast   319 GESSPAEVPKNETPAAQEQPMPDNEPKQGDTSIQIRYANGKREVLHCNSTDTVKFLYEHVTSNAN 383

  Fly   296 EFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVVIQ 333
            ....|:|.|..|||.:. :.:|..||..|:|.|.||:|
Yeast   384 TDPSRNFTLNYAFPIKP-ISNDETTLKDADLLNSVVVQ 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459	10/28 (36%)
		SEP	155..242	CDD:197786	30/91 (33%)
		UBX_UBXN2	262..334	CDD:340468	25/72 (35%)
SHP1	NP_009495.1	UBA_Ubx1_like	6..41	CDD:270536	10/34 (29%)
		SEP	231..323	CDD:197786	30/91 (33%)
		UBX_UBXN2	350..421	CDD:340468	25/72 (35%)