| Sequence 1: | NP_523847.2 | Gene: | CG42383 / 37897 | FlyBaseID: | FBgn0259729 | Length: | 353 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001102952.1 | Gene: | Ubxn2a / 685859 | RGDID: | 1589027 | Length: | 258 | Species: | Rattus norvegicus |
| Alignment Length: | 238 | Identity: | 70/238 - (29%) |
|---|---|---|---|
| Similarity: | 113/238 - (47%) | Gaps: | 38/238 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 135 PINPPPRSATE---DSDTEPAD------------DEHTIVVLHLWSEGFSLDDGSLRLYALPENE 184
Fly 185 RFLRAILRGDFPEEMLRV---PRVQLSVQDHTNESYRHLSRK----QFMGPGRPLNSPSPQILVV 242
Fly 243 GPMPVEA------QGLQLNERADTTTVQLRMADGSRVAGRFNLTHNVGDLYQYARLARPEFSDRS 301
Fly 302 --FVLMTAFPRQELVESDTRTLVQANLCNVVVIQHLNEEQVEP 342 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG42383 | NP_523847.2 | UBA_TAP-C_like | 10..39 | CDD:270459 | |
| SEP | 155..242 | CDD:197786 | 29/93 (31%) | ||
| UBX_UBXN2 | 262..334 | CDD:340468 | 24/73 (33%) | ||
| Ubxn2a | NP_001102952.1 | Required for inhibition of CHRNA3 ubiquitination and translocation of CHRNA3 to the plasma membrane resulting in an increase in acetylcholine-gated nicotinic acetylcholine receptor currents. /evidence=ECO:0000250|UniProtKB:Q99KJ0 | 1..165 | 39/143 (27%) | |
| Required for interaction with CHRNA3. /evidence=ECO:0000250|UniProtKB:P68543 | 1..152 | 38/130 (29%) | |||
| SEP | 66..139 | CDD:462348 | 23/75 (31%) | ||
| Required for interaction with VCP. /evidence=ECO:0000250|UniProtKB:P68543 | 168..258 | 31/91 (34%) | |||
| UBX_UBXN2A | 168..251 | CDD:340680 | 29/86 (34%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||