DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42383 and Ubxn2a

DIOPT Version :9

Sequence 1:	NP_523847.2	Gene:	CG42383 / 37897	FlyBaseID:	FBgn0259729	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001102952.1	Gene:	Ubxn2a / 685859	RGDID:	1589027	Length:	258	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	71/242 - (29%)
Similarity:	111/242 - (45%)	Gaps:	46/242 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 PINPPPRSATE---DSDTEPAD------------DEHTIVVLHLWSEGFSLDDGSLRLYALPENE 184
            |:|..|:...|   ||..|.|:            .:...|.:.||..||:::| ..|.|:...::
  Rat    25 PLNDNPQKDCEYFVDSLFEEAEKAGAKCLSPTEQKKQVDVNIKLWKNGFTVND-DFRSYSDGASQ 88

  Fly   185 RFLRAILRGDFPEEMLRV---PRVQLSVQDHTNESYRHLSRK----QFMGPGRPLNSPSPQILVV 242
            :||.:|.:|:.|.|:..|   ..|.:.|:|..||..  :|.|    .|.|.|..|.|.:|:| |.
  Rat    89 QFLNSIKKGELPSELQGVFDKDEVDVKVEDKKNEVC--MSTKPVFQPFSGQGHRLGSATPRI-VS 150

  Fly   243 GPMPVEA------QGLQLNERADTTTVQLRMADGSRVAGRFNLTHNVGDL------YQYARLARP 295
            ....:|.      ..:.||.....|.:|:.:|:|.|...|||::|.|..:      ||..:.:.|
  Rat   151 KAKSIEVDNKSTLSAVSLNNLEPITRIQIWLANGERTVQRFNISHRVSHIKDFIEKYQGTQRSPP 215

  Fly   296 EFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVVIQHLNEEQVEP 342
                  |.|.||.|....:: :|.||.:|:|.|.|:||.| ::..||
  Rat   216 ------FALATALPFLRFLD-ETLTLEEADLQNAVIIQRL-QKTAEP 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459
		SEP	155..242	CDD:197786	29/93 (31%)
		p47_UBX	257..336	CDD:176365	27/84 (32%)
Ubxn2a	NP_001102952.1	SEP	66..139	CDD:400413	23/75 (31%)
Ubxn2a	NP_001102952.1	UBX_UBXN2A	168..251	CDD:340680	30/90 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.870