DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42383 and Ubxn11

DIOPT Version :9

Sequence 1:	NP_523847.2	Gene:	CG42383 / 37897	FlyBaseID:	FBgn0259729	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_080533.1	Gene:	Ubxn11 / 67586	MGIID:	1914836	Length:	484	Species:	Mus musculus

Alignment Length:	405	Identity:	79/405 - (19%)
Similarity:	132/405 - (32%)	Gaps:	128/405 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 YESEAVSKKQEPEKSSEHSQANESNRDLHSLLSEISRRKEGDHDGYQACASDSSTDHDTPAGKRV 103
            :::.|..::|| |..::..|......::...||:...:..|:                 |..:.
Mouse   115 HQNNAALQRQE-ELETQCIQLQRQIGEMERFLSDYGLQWVGE-----------------PMDQE- 160

  Fly   104 NINSSTPAITNNDSD---RSLRVWGHGNRL----------------------GSAHPINPPPRSA 143
              ||....::.||..   ::.:.|..|:..                      |.|. :.|.|..|
Mouse   161 --NSEEKTVSENDERDWMKAKKFWKPGDSFVPPEVDFDKLMASLQDLSELVEGEAQ-VTPVPGGA 222

  Fly   144 TEDSDTEPADDEHTIVVLHLWSEGFSLDDGSLRLYALPENERFLRAILRGDFPEEMLRV--PRVQ 206
             .....||       :.|.::..|..:.||..|.:..|..:|.||.||.|.||.|:.|:  ..|.
Mouse   223 -RFRTLEP-------IPLKVYRNGIMMFDGPFRPFYDPSTQRCLRDILDGFFPSELQRLYPDGVP 279

  Fly   207 LSVQDHTNESYRHLSRKQFMGPGRP--------------------------LNSPSPQILVVG-- 243
            ..|.|..|:.|......||.|.||.                          ||.....|:..|
Mouse   280 FKVSDLRNQIYPEDGLGQFPGEGRVVGRQKMRKVTDRVEETSGSRMTAEQFLNRLPKCIIRQGEV 344

  Fly   244 ---------------PMPVEAQGL------------QLNERAD-----TTTVQLRMADGSRVAGR 276
                           |||...|.:            :..|..|     .:.::::..:|.:.
Mouse   345 IDIRGPIRDTLQNCCPMPARIQEIIVETPALASERQRSQESPDMPMPLLSMLRIKSENGEQA--- 406

  Fly   277 FNL----THNVGDLYQYARLARPEFSDRSFVLMTAFPRQELVESDTRTLVQANLC-NVVVIQHLN 336
            |.|    ...:||:.:....|| :....:|.:::.|| ..:.:.||.||..|.|. |..::....
Mouse   407 FLLMMWPEDTIGDVRKLLAQAR-DMDSAAFEILSTFP-PTVYQDDTVTLQAAGLVPNATLLLRTR 469

  Fly   337 EEQV-EPLSSDASEP 350
            ...: .|:|...|.|
Mouse   470 RALLSNPISRPGSLP 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459	79/405 (20%)
		SEP	155..242	CDD:197786	29/114 (25%)
		p47_UBX	257..336	CDD:176365	18/88 (20%)
Ubxn11	NP_080533.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		NADB_Rossmann	<172..225	CDD:304358	7/54 (13%)
		SEP	232..302	CDD:285322	24/69 (35%)
		UBQ	394..461	CDD:294102	16/71 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900