DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42383 and Nsfl1c

DIOPT Version :9

Sequence 1:	NP_523847.2	Gene:	CG42383 / 37897	FlyBaseID:	FBgn0259729	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_938085.1	Gene:	Nsfl1c / 386649	MGIID:	3042273	Length:	372	Species:	Mus musculus

Alignment Length:	383	Identity:	120/383 - (31%)
Similarity:	179/383 - (46%)	Gaps:	60/383 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTDEQK--LSTFMKRHGVREEVARQYLSSNNWSLEVA-SSTYE----SEAVSKKQEPEKSSEHSQ 58
            |.:|::  |..|:...|..|:.||.:|.|..|.|::| :|.||    .:.|:..|....|.....
Mouse     1 MAEERQDALREFVAVTGTEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGT 65

  Fly    59 ANESN-----RDLHSLLSEISRRKEGDHDGYQACASDSS------------------------TD 94
            |...|     |||.....|....:||....:.|..|:.|                        .:
Mouse    66 APSDNRVTSFRDLIHDQDEEEEEEEGQRSRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKE 130

  Fly    95 HDTPAGKRVNINSSTPAITNNDSDRSLRVWGHGNRLGSAHPINPPPRSATEDSDTEPADDEHTIV 159
            |...|.:||   :.:|..|:.....:    |.|.|||:|    |...||....:......:...|
Mouse   131 HGAVAVERV---TKSPGETSKPRPFA----GGGYRLGAA----PEEESAYVAGERRRHSGQDVHV 184

  Fly   160 VLHLWSEGFSLDDGSLRLYALPENERFLRAILRGDFPEEMLRVP---RVQLSVQDHTNESY--RH 219
            ||.||..|||||:|.||.|..|.|.:||.:|.||:.|.|:.|:.   :|.|.::||.:|.:  ..
Mouse   185 VLKLWKTGFSLDNGDLRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPK 249

  Fly   220 LSRKQFMGPGRPLNSPSPQILVVGPMPVEAQ-------GLQLNERADTTTVQLRMADGSRVAGRF 277
            .:.|.|.|.|:.|.|.:||:|.......:|:       .:.:||...||.:|:|:|||.|:..:|
Mouse   250 GAFKAFTGEGQKLGSTAPQVLNTSSPAQQAENEAKASSSILINEAEPTTNIQIRLADGGRLVQKF 314

  Fly   278 NLTHNVGDLYQYARLARPEFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVVIQHL 335
            |.:|.:.|:..:...|||..:..||||||.||.:||.: :.:||.:|||.|.|::|.|
Mouse   315 NHSHRISDIRLFIVDARPAMAATSFVLMTTFPNKELAD-ENQTLKEANLLNAVIVQRL 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459	11/29 (38%)
		SEP	155..242	CDD:197786	38/91 (42%)
		p47_UBX	257..336	CDD:176365	34/79 (43%)
Nsfl1c	NP_938085.1	UBA_p47	7..45	CDD:270533	14/37 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	54..73		4/18 (22%)
		Nuclear localization signal	111..117		0/5 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	140..159		4/22 (18%)
		Nuclear localization signal	174..177		0/2 (0%)
		SEP	180..272	CDD:197786	38/91 (42%)
		p47_UBX	294..372	CDD:176365	34/79 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833363
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54012
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001623
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102041
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.700