DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42383 and Ubxn2b

DIOPT Version :9

Sequence 1:	NP_523847.2	Gene:	CG42383 / 37897	FlyBaseID:	FBgn0259729	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001101375.1	Gene:	Ubxn2b / 312965	RGDID:	1308557	Length:	331	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	108/334 - (32%)
Similarity:	162/334 - (48%)	Gaps:	58/334 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 EPEKSSEHSQANE--SNRDLHSLLSEI----SRRKEGDHDGYQACASDS---------STDHD-- 96
            |||:....|....  |.|||...|:|:    .:.|....|...|.|..|         |.|.:
  Rat     8 EPEEQERRSSRPRPPSARDLQLALAELYEDEMKCKSSKPDRSTATAFKSPRTPPLRLYSGDQEYG 72

  Fly    97 ------TPAGKRVN-------------INSSTPAITNNDSDRSLRVWGHGNRLGSAHPINPPPRS 142
                  .|.||.||             :|.:|   .::..|::....|.|.||||:.    ..||
  Rat    73 GLHIAQPPTGKIVNELFKEAREHGAVPLNEAT---RSSSDDKAKSFTGGGYRLGSSF----YKRS 130

  Fly   143 ATEDSDTEPADDEHTIVVLHLWSEGFSLDDGSLRLYALPENERFLRAILRGDFPEEMLRV---PR 204
            .....:.:..|.:   ::|.|||.|||||||.||.|:.|.|.:||.::.||:.|.|:.|:   .:
  Rat   131 EYIYGENQLQDVQ---ILLRLWSNGFSLDDGELRPYSDPTNAQFLESVKRGEIPLELQRLVHGSQ 192

  Fly   205 VQLSVQDHTNESY--RHLSRKQFMGPGRPLNSPSPQILVVGPMPVEAQGLQLN------ERADTT 261
            |.|.::||.::.|  ..|..|.|.|.|:.|.|.:|:|:.....|.|.....||      :...||
  Rat   193 VSLDMEDHQDQEYIKPRLRFKAFSGEGQKLGSLTPEIVSTPSSPEEEDKSILNAAVLIDDSVPTT 257

  Fly   262 TVQLRMADGSRVAGRFNLTHNVGDLYQYARLARPEFSDRSFVLMTAFPRQELVESDTRTLVQANL 326
            .:|:|:|||||:..|||.||.:.|:..:...:||||:...|:|:|:||.:||.: ::.||..|::
  Rat   258 KIQIRLADGSRLIQRFNSTHRILDVRDFIVQSRPEFATTDFILVTSFPSKELTD-ESVTLQDADI 321

  Fly   327 CNVVVIQHL 335
            .|.|::|.|
  Rat   322 LNTVILQQL 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459
		SEP	155..242	CDD:197786	37/91 (41%)
		p47_UBX	257..336	CDD:176365	33/79 (42%)
Ubxn2b	NP_001101375.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		5/17 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..63		5/24 (21%)
		SEP	140..232	CDD:197786	38/94 (40%)
		p47_UBX	253..331	CDD:176365	33/79 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336919
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	1	1.000	-	-		FOG0001623
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23333
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.900