Protein Alignment Slik and map3k3

DIOPT Version :10

• Sequence 1: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: XP_688694.2
• Gene: map3k3 / 560211
• ZFINID: ZDB-GENE-070910-1
• Length: 620
• Species: Danio rerio
• Alignment Length: 278
• Identity: 92/278 - (33%)
• Similarity: 139/278 - (50%)
• Gaps: 21/278 - (7%)

  Fly    28 KMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQL-----EDEENLSDHMVEIDILS 87
            |..|.|.. |.....||.||||:||.....:..|..|||....     |..:.:|....||.:|.
Zfish   348 KSPTAPVT-WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVHFDPASPETSKEVSALECEIQLLK 411

  Fly    88 EIKHPNIVELYEAFSIDDK--LWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLH 150
            .:.|..||:.|......::  |.:.:||..||::.. .::....|||.......:.:.||:::||
Zfish   412 NLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKD-QLKAYGALTENVTRKYTRQILEGMSYLH 475

  Fly   151 RNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFI----GTPYWMAPELVLCETFR 211
            .|.::|||:|..|:|....|.|||.|||.| |...|:....|.:    ||||||:||::..|
Zfish   476 SNMIVHRDIKGANILRDSAGNVKLGDFGAS-KRLQTICMSSTGVRSVTGTPYWMSPEVISGE--- 536

  Fly   212 DNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSL 276
              .|..|.|:||||.|::|:...:||.:|...|..:.|| .::|...:.||..|:...|||:...
Zfish   537 --GYGRKADVWSLGCTVVEMLTEKPPWAEFEAMAAIFKI-ATQPTNPQLPSHISEHTRDFLRCIF 598

  Fly   277 VKDPQVRPTTDVLMQHAF 294
            | :.:.||:.:.|::|.|
Zfish   599 V-EAKYRPSAEELLRHPF 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	91/275 (33%)
		PKK	958..1095	CDD:463600
		PKK	1126..1266	CDD:463600
map3k3	XP_688694.2	PB1_Mekk2_3	48..126	CDD:99726
		STKc_MEKK3_like	356..615	CDD:270795	88/267 (33%)