Protein Alignment Slik and hpo

DIOPT Version :10

• Sequence 1: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_611427.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 897
• Identity: 210/897 - (23%)
• Similarity: 327/897 - (36%)
• Gaps: 302/897 - (33%)

  Fly    33 PAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVEL 97
            |.:.::::.:||:|::|.||||.|||.....|.|:..:|.:  |.:.:.||.|:.:...|.:|..
  Fly    38 PEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESD--LHEIIKEISIMQQCDSPYVVRY 100

  Fly    98 YEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAG 162
            |.::.....||:.:|||..|::..||...:|.|||.:||.:.....:||.:||..:.||||:||.
  Fly   101 YGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAA 165

  Fly   163 NVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGIT 227
            |:||..||..|||||||:.:...||.|.:|.||||:|||||::     .:..||...||||||||
  Fly   166 NILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI-----EEIGYDCVADIWSLGIT 225

  Fly   228 LIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQH 292
            .:|:|:.:||..|:.|||.:..|.:..||...:|.|||.||.||:.|.|||:|..|.|...|::|
  Fly   226 ALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEH 290

  Fly   293 AFINRNLDAKPIKDLLLEYKAEVVEEVVDDETEEPRNSALQLDLDDDSASLQSQDIDKLPGTPTS 357
            .|| ||...:.|...:||....:
  Fly   291 EFI-RNAKHRSILKPMLEETCAI------------------------------------------ 312

  Fly   358 ILRDAKEQSQPSSSL-PIAAAATAAAAATTTTKATTPDRPNHTKDDNAEAAAQQPPHTKVPAPAP 421
                 :||.:.:.|. .:.||:.|.:.||         :.|..:....:.|..:.|.|.||
  Fly   313 -----REQQRANRSFGGVLAASQAKSLAT---------QENGMQQHITDNAFMEDPGTLVP---- 359

  Fly   422 PSSQQTPPPQVQQPPTPPAQPTAAVLQKKPEDVAAVAETSEKTESDKKHFVKKGKAPPPPSPLGL 486
                               :......|....|...:|...:.        |.:|..    .|.||
  Fly   360 -------------------EKFGEYQQSSASDATMIAHAEQG--------VDEGTL----GPGGL 393

  Fly   487 AN----AKPAASDSQTSPKKLATPEPTSPVTTAIEVAIGQEAMEPKPQPPSPTASSIVSVQSVAS 547
            .|    |.|||:.|..||..:                            |:..:.::|.::|
  Fly   394 RNLSKAAAPAAASSAASPLDM----------------------------PAVDSGTMVELES--- 427

  Fly   548 SSSSGSVSNAVLSSSTSLITINSDPPTPHHHQPLPPQPQHLILPNSLESVSQITVVTSTHPPVII 612
                        :..|.:|..:||..|...:.. ..:|::...|..||
  Fly   428 ------------NLGTMVINSDSDDSTTAKNND-DQKPRNRYRPQFLE----------------- 462

  Fly   613 DNSVMPPQNEVIIVSNDMNKSTHLHESSTDDDFPSLDDSLGDATTPPHKQSSMILAVNEPAGVVP 677
                                  |.       |..:..|..||        ...|.....||
  Fly   463 ----------------------HF-------DRKNAGDGRGD--------EKPIATEYSPA---- 486

  Fly   678 APPSQPQTSSTVHARKLDESEVLIVSPSYADDDSAYNTASGSHSHDHSDHLMDTSHVSVVTVGDE 742
            |...|.|.......::.||..:                |||::..::.:|.|:.....:..:...
  Fly   487 AAEQQQQQQQQQQQQQQDEQHL----------------ASGANDLNNWEHNMEMQFQQISAINQY 535

  Fly   743 GVKVKDSSNELVKRQPNGVGIVPEDVNIIVNRFKQEKRSPDSSLSENGSVRGRRGIEVLVGGSGG 807
            |::......:::...|    ::.|.:..:.|:       |:..|| |.:..|::||
  Fly   536 GLQQHQQQQQVLMAYP----LMNEQLIALNNQ-------PNLLLS-NAAPMGQQGI--------- 579

  Fly   808 SDVDSIGTNTSQESRHETDHNNKQQYPAAALMPPPPPSLTNNHNHE------------------- 853
                                      |||| ...|||:..|.|.|.
  Fly   580 --------------------------PAAA-PAQPPPAYQNQHMHTQSHAYVEGEFEFLKFLTFD 617

  Fly   854 -------TIDEEEEVVI-----RPKARVPAVVKSANAQGLTKEEIELRNLRK 893
                   .||.|.|:.|     :..|:...:|.:.||:...::.|. .||.|
  Fly   618 DLNQRLCNIDHEMELEIEQLNKKYNAKRQPIVDAMNAKRKRQQNIN-NNLIK 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	114/276 (41%)
		PKK	958..1095	CDD:463600
		PKK	1126..1266	CDD:463600
hpo	NP_611427.1	STKc_MST1_2	38..293	CDD:132943	109/261 (42%)
		SARAH_Hpo	606..661	CDD:439183	9/54 (17%)