|
Fly 1 MSFITNLKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAA 65
|||:.|||||||||.|||||||::|||:||||||:||:|:|||||||||||||||::|.|:.|||
Mosquito 1 MSFLNNLKKVFHLGSGEAKKKRIFNNIRMDTDPADFWDMIGELGDGAFGKVYKAQNRETKQLAAA 65
Fly 66 KMCQLEDEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPL 130
|||.||||||||||||||||||||||||||.||||:|||||||||||||||||||||||||||||
Mosquito 66 KMCTLEDEENLSDHMVEIDILSEIKHPNIVGLYEAYSIDDKLWMLIEYCDGGALDSIMVELEKPL 130
Fly 131 TEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIG 195
||.|||||||||..||..||:|||||||||||||||||:||||||||||||||||||||||||||
Mosquito 131 TEAQIAYVCKHMCAGLNHLHKNKVIHRDLKAGNVLLTMDGGVKLADFGVSAKNKHTMQKHDTFIG 195
Fly 196 TPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQ 260
|||||||||||||||||||||.|||||||||||||.|||||||||||||||||||||||||||:|
Mosquito 196 TPYWMAPELVLCETFRDNPYDFKVDIWSLGITLIEFAQMEPPNSEMSPMRVLLKIQKSEPPKLDQ 260
Fly 261 PSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFINRNLDAKPIKDLLLEYKAEVV-EEVVDDET 324
||:|||.|||||.::||||||.||:|:|||..:||:.|||:||||||||||||:|| ||:||:|.
Mosquito 261 PSKWSKHFNDFLARALVKDPQQRPSTEVLMGLSFISGNLDSKPIKDLLLEYKADVVEEELVDEEA 325
Fly 325 E--------------EPRNSALQLDLDDDSASLQSQDIDKLPGTPTSI---LRDAKE-------Q 365
| |||||||.|||||||:|||||:.||||.||||: .||:|| :
Mosquito 326 EKAKRQAKRRSLYQREPRNSALPLDLDDDSSSLQSQETDKLPDTPTSLSKSSRDSKESTPVPTTE 390
Fly 366 SQPSSSLPIAAAATAAAAATTTTKATTPDRPNHTKDDNAEAAAQQPPHTKVPAPAPP-------S 423
..||.| .|..|.|...|..:...|.. :.|..:.|...|....|| .|:|||| |
Mosquito 391 DDPSKS-KIGPAPTTVGAPGSAGAAPL-EAPPPSVDTKTEMKKSQP----APSPAPPPVVASPVS 449
Fly 424 SQQTPPPQVQ-------------QPPTP---------PAQPTAAVL----------QKKPEDVAA 456
::.|....:: ..||| |.||:...| |:| :||
Mosquito 450 AEGTQETTIKTSSSSSNISGGAVNVPTPVLPVAKEIVPEQPSTGELHAETPGGGNEQRK---IAA 511
Fly 457 VAETSEKTESDKKHFVKKGKAPPPP----SPLG------LANAKPAASD--SQTSPKKLATPEPT 509
...|..... ||||.||||| ||.| |......|.| ..|.|:...||...
Mosquito 512 AGGTFSTAA------VKKGPAPPPPQTPTSPTGRQTSAKLTFGGSVAKDVVPPTPPETPQTPPAG 570
Fly 510 SPVTTAIE------------------------VAIGQEAMEPK----PQPPS------------- 533
.|...|:: ..|.::...|: |.|||
Mosquito 571 EPPAKALDRPDAKALDGTMPPPPPALMRMGSSGVIEEQTKSPRKEHAPTPPSDKESPKASTPPGA 635
Fly 534 -PT--------------------------------ASSIV-------SVQSVASSSSSGSVSN-- 556
|| .||:| .|:.:.::|:..:|.|
Mosquito 636 KPTINVHEHPSSPKTNQAFAMSSTNNVAIPRAVHPPSSLVEEGGVDEGVKMITTTSTPSTVRNQL 700
Fly 557 ---AVL-----SSSTSLITIN-----SDPPTPHHHQPLPPQPQHLILPNSLES-VSQITVVTSTH 607
|.| ||||:.|||| ||| .|||.| |:|:||||| |
Mosquito 701 PHHATLMNTSSSSSTTSITINDAAVLSDP------------------SNSLASNVAQVTVVTS-H 746
Fly 608 PPVIIDNSV-MPP--------------------------------------QNEVIIVSNDMNKS 633
||||||||: :|| .:||:||||::||
Mosquito 747 PPVIIDNSIPLPPAAAAAASSGTSSSASSTKSFGSSQLRRSRVISPPGTGAHDEVVIVSNELNK- 810
Fly 634 THLHESSTDDDFPSLDDSLGDATTPPHKQSSMILAVNEPAGVVPAPPSQPQTSSTVHARKLDESE 698
||::||||||||.|| |||.:.:...|...:: ||........||||||||
Mosquito 811 THVNESSTDDDFQSL-DSLENVSPRHHPIRTL---------------SQSVAGGRAIARKLDESE 859
Fly 699 VLIVSPSYAD-----------------------DDSAYNTASGSHSHDHSDHLMDTSHVSVVTVG 740
|||||..|.| |...:|.:..:..::.|..|:|||||||||||
Mosquito 860 VLIVSSGYDDRREVLLVDDTNASSPDRDVDAYGDGDVFNASGHNLLNNSSKLLLDTSHVSVVTVG 924
Fly 741 DEGVKVKDSSN---ELV-----------------------------------------KRQP--- 758
:|.:||||||. :|: ::||
Mosquito 925 EEEIKVKDSSQHHPQLINNPHASSPHHYHHDSTSDLSNVSCGPSESSDDVKVDIVVGGRQQPSHQ 989
Fly 759 --------------------------NGVGIV--------------PEDVNIIVNRFKQEKR--S 781
:|.||: .|||:||||:.|.||. |
Mosquito 990 QQQHPQQRSPSGSSISLPSQTGKGGASGGGIINGNRYNGGSEFHQSREDVSIIVNKRKIEKSRIS 1054
Fly 782 PDS---SLSENGSVR-------------GRRGIEVLVG-------GSGG---------------S 808
||| ||...|||| |.....:::| ||.| |
Mosquito 1055 PDSSVGSLEGGGSVRSASTPIHQNHQQHGSAAGGMVIGGNHHQRTGSSGTTPLAVSAKHHLYDRS 1119
Fly 809 DVDSIGTNTSQESRHETDHNNKQQYPAAALMPPPPPSLTNNHNHETIDEEEEVVIRPKA------ 867
|.:||.|.||.:|| .|.:::.||||.:|.|.
Mosquito 1120 DAESIATTTSHDSR----------------------------EHASVELEEEVTLRRKPMPSLDL 1156
Fly 868 ---RVPAVVKSANAQG------------------------------------------------- 880
:||.:...|.:.|
Mosquito 1157 DDDKVPVLAAGATSSGSSTLVSSSAGGNAPATATAGTPGAAGGVAAAAGTGAAAAGGNGTAGIRQ 1221
Fly 881 -----LTKEEIELRNLRKKTRKRTRKFEIDGVQMTTTTSRVIYGDDENGRIYDDHDFRKQELREL 940
::|||:.|:||:||||||||||||||||:|||||:|||.|::|.::||||.|||||||||
Mosquito 1222 KANRNISKEELHLQNLKKKTRKRTRKFEIDGVQVTTTTSKVIYSDEDNNKLYDDHLFRKQELREL 1286
Fly 941 KLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENE 1005
|:||||||||..:|..||..|||||:::|||||..||:|:|||||:|||||:|.|||.||.||.|
Mosquito 1287 KMLQKQEKKQFYDLQGKEAIAKEQQEKKFEQERLQLERTFEADMDVLARQHRQTVEKFEQQQEAE 1351
Fly 1006 LRSSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFL 1070
||::||:||:|||::||:||::||||||||||||||.||:||||||::|::.||.:|||:|::||
Mosquito 1352 LRNTSKKIRAEQERDLKLFRDSLKQEIRLLKQEVDLLPKEKRKDEFRKRKTQMEFEHEEREKSFL 1416
Fly 1071 DSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKE 1135
.||.|.|||.|||:||.:|:.|:..::.:|||||.|||||||:|||||||.:|::|||:|||||:
Mosquito 1417 SSLSENHELALRRISEIYREKLSATDKGYLQQKQTAMRTREAMLWELEEKHIHDKHQLAKRHVKD 1481
Fly 1136 LCFMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRIST 1200
:||||||||||||||||||:|||:.||||:::|:||:|:|||||||||||||||:|||||||||.
Mosquito 1482 ICFMQRHQMIIRHEKELDQIKRMITRKEEELLKRQTIERRALPKRIRAERKARDMMFRESLRISM 1546
Fly 1201 NLDPEIERDRLKKFQEQEKKRYMQEERRFEVKHQKQLEELRATRESAIKELEQLQNEKRRALVEH 1265
..|||:|||:||||||||||||.||:.|||.||.|||||||||.|.:|:||||||||||:.|:||
Mosquito 1547 TTDPEVERDKLKKFQEQEKKRYNQEQLRFETKHSKQLEELRATSEGSIRELEQLQNEKRKQLLEH 1611
Fly 1266 EHSKLSEIDERLKGELREWREQLVPRKQELNRQIKLAIDQHEKRFGLVTNREEFEDQEVKLPAHL 1330
|.:||.|.||.|:.|||||:.||:||||.:.:.:...:|::|.|:|.| :|.|| |.:..:|..|
Mosquito 1612 ETAKLRECDEALQKELREWKAQLMPRKQAIEKHLSRMVDEYEDRWGPV-DRREF-DGDFTVPPEL 1674
Fly 1331 R---NIYNERSSRILPRNTFIDPQNMPRSRSSLLM---------------MGGGG---NRLSNFR 1374
| |..|..|.|:| |:.|||:.|.: .|||| || ::..
Mosquito 1675 RNRTNSLNTLSLRLL---------NITRSRTFLTLPTMANGGVAGGGGGGYGGGGSSSNR-NSIH 1729
Fly 1375 GSAPDLSRSVPNTPIM-HKQQRSQMIGDQVLEEDEEQMLSEQMKRASVATLPAQNQLRLITQLPA 1438
.|.||||||:||||.. ||...:... |.||||:|.:
Mosquito 1730 SSVPDLSRSMPNTPNSGHKLSLASSY-DSVLEENEGE---------------------------- 1765
Fly 1439 NELVKVVTSTPPLNSAEDVNSKPSMSTFRGSTPPKTPDDLGLVTNRFSR----LDTKAAAEASGV 1499
|..|:|.|.||. .|..|...|::.. :.|.....|:.|
Mosquito 1766 -------------------NQPPTMVTGRGG-----DDARGYGNNQYQSAIKYIHTNDPVVANNV 1806
Fly 1500 ELRIHEGPVLTAHTQRLLHTTSFAIK------RPSLASRSSGRSSLSSAQ--------------- 1543
.:|.....:|:..:: :|...|| .|..:.|:...||.|||.
Mosquito 1807 HVRRKSEDMLSGKSR----STRIPIKSFLFSNTPVRSGRNEYGSSSSSAYYGGGGGEYGVSRGTP 1867
Fly 1544 -----SMYNINE---LSTRFTSDADLIFDSGRKAAALLDEVQPQLRSSVKPGHSRANGSVVSADS 1600
|.|:.:: :|.|..:.| :.||.|.:.|.:.. ||::...|..|:|..:...:
Mosquito 1868 SGGPLSYYSDSKDRVVSIRVNNQA-----TNRKPANMFDGITN--RSNIPQSHQSASGGTMPRRT 1925
Fly 1601 AA 1602
:|
Mosquito 1926 SA 1927
| 
