Protein Alignment Slik and taok2b

DIOPT Version :10

• Sequence 1: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: XP_009304676.2
• Gene: taok2b / 100151551
• ZFINID: ZDB-GENE-110603-3
• Length: 1247
• Species: Danio rerio
• Alignment Length: 1460
• Identity: 287/1460 - (19%)
• Similarity: 488/1460 - (33%)
• Gaps: 553/1460 - (37%)

  Fly    32 DPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQL---EDEENLSDHMVEIDILSEIKHPN 93
            ||.:.:..:.|:|.|:||.||.|.........|.|....   :..|...|.:.|:..|.:::|||
Zfish    23 DPEKLFTDLREIGHGSFGAVYFAHDIRTNEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQKLRHPN 87

  Fly    94 IVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRD 158
            .||....:..:...|:::|||.|.|.|.:.|. :|||.|.:||.:.....:||.:||.:.:||||
Zfish    88 TVEYRGCYLREHTAWLVMEYCLGSASDLLEVH-KKPLQEVEIAAITHGALQGLVYLHSHNMIHRD 151

  Fly   159 LKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWS 223
            :||||:|||..|.|||.|||.::    .:...::|:|||||||||::|  ...:..||.|||:||
Zfish   152 VKAGNILLTEPGQVKLGDFGSAS----IVAPANSFVGTPYWMAPEVIL--AMDEGQYDGKVDVWS 210

  Fly   224 LGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDV 288
            ||||.||||:.:||...|:.|..|..|.::|.|.| |.:.||..|.:|:...|.|..|.|||:||
Zfish   211 LGITCIELAERKPPLFNMNAMSALYHIAQNESPVL-QSNHWSDYFRNFVDSCLQKISQDRPTSDV 274

  Fly   289 LMQHAFINRNLDAKPIKDLLLEYKAEVVEEVVDDETEEPRNSALQLDLDDDSASLQSQDIDKLPG 353
            |::|.|:.|......:.||:...|..|.|                  ||    :||.:.:.|:
Zfish   275 LLKHHFLCRERPVTVVMDLIARTKDAVRE------------------LD----NLQYRKMKKI-- 315

  Fly   354 TPTSILRDAKEQSQPSSSLPIAAAATAAAAATTTTKATTPDRPNHTKDDNAEAAAQQPPHTKVPA 418
                                                                             
Zfish   316 ----------------------------------------------------------------- 315

  Fly   419 PAPPSSQQTPPPQVQQPPTPPAQPTAAVLQKKPEDVAAVAETSEKTES----DKKHFVKKGKAPP 479
                        ..|:....||                 .|.:|:.||    |.:.::.:
Zfish   316 ------------LFQETHNGPA-----------------TEGTEEEESCVFQDVEQYMLR----- 346

  Fly   480 PPSPLGLANAKPAASDSQTSPKKLATPEPTSPVTTAIEVAIGQEAMEPKPQPPSPTASSIVSVQS 544
                .|..|                                   :||.....||         .|
Zfish   347 ----TGTVN-----------------------------------SMESSHSLPS---------MS 363

  Fly   545 VASSSSSGSVSNAVLSSSTSLITINSDPPTPHHHQPLPPQPQHLILPNSLESVSQITVVTSTHPP 609
            :::||.|.||                                     |||...|
Zfish   364 ISASSQSSSV-------------------------------------NSLADGS----------- 380

  Fly   610 VIIDNS---VMPPQNEVIIVSNDMNKSTHLHESSTDDDFPSLDDSLGDATTPPHKQSSMILAVNE 671
               |:|   .|..:.|..:.||    |:.||::...|:.  .||
Zfish   381 ---DDSGEMAMMQEGEHTVTSN----SSVLHKALNHDNI--YDD--------------------- 415

  Fly   672 PAGVVPAPPSQPQTSSTVHARKLDESEVLIVSPSYADDDSAYNTASGSHSHDHSDHLMDTSHVSV 736
                    |.||:                                            ||:.
Zfish   416 --------PYQPE--------------------------------------------MDSQ---- 424

  Fly   737 VTVGDEGVKVKDSSNELVKRQPNGVGIVPEDVNIIVNRFKQEKRSPDSSLSENGSVRGRRGIEVL 801
                                                   :|:::.|..         |||
Zfish   425 ---------------------------------------QQQQQGPSG---------GRR----- 436

  Fly   802 VGGSGGSDVDSIGTNTSQESRHETDHNNKQQYPAAALMPPPPPSLTNNHNHETIDEEEEVVIRPK 866
                                |...||.
Zfish   437 --------------------RRGRDHF-------------------------------------- 443

  Fly   867 ARVPAVVKSANAQGLTKEEIELRNLRKKTRKRTRKFEIDGVQMTTTTSRVIYGDDENGRIYDDHD 931
                |.:::|:   |...:|:                                :.|.|...
Zfish   444 ----ATIRTAS---LVTRQIQ--------------------------------EHEQGSAL---- 465

  Fly   932 FRKQELRELKLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVE 996
              ::::...|.:::|.:||...|..|.:...::...|.::|..:....:.::.|.|:::|:.::|
Zfish   466 --REQMSGYKRMRRQHQKQLMALENKLKAEMDEHQLRLDKELETQRNNFGSEADKLSKKHQAILE 528

  Fly   997 KTEQTQENELRSSSKRIRSEQEQELKIFRENLKQEIR----LLKQEVD---LFPKDKRKDEFKQR 1054
            |..:....|.:...:.|..:|::||....|:.|:..|    .||:|::   ..||.::::...|:
Zfish   529 KETKGAIAEEKKFQQHILGQQKKELTSLLESQKRHYRQRKEQLKEELNENQSTPKREKQEWLVQQ 593

  Fly  1055 RSAMELDHEEKERAFLDSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEE 1119
            :..::....|:|...|...::.:||..|:...|.......:.::.|::..|..:|    |.:||.
Zfish   594 KECLQQVQAEEEAGLLRRQRQYYELQGRQYKRKMLLSRHNLEQDLLREDLNKKQT----LKDLEC 654

  Fly  1120 KQLHERHQLSKR-HVKELCFMQRHQM-IIR--HEKELDQVKRMLQRKEEDMVKKQTMEKRALPKR 1180
            ..|...|:.::. ..::|..:||.:. :||  |:.||.......:|:|:::.:|..:|.|..||.
Zfish   655 AMLLRHHESTQELEFRQLALVQRTRADLIRTQHQTELTNQMEYNKRREQELRQKHAVEVRQQPKS 719

  Fly  1181 IRAERKARDLMFRESLRISTNLDPE-IERDRLKKFQEQEKKRYMQEERRFEVKHQKQLEELRATR 1244
            :|..    |....|:......||.| :|.      |::||:    :..:.:....:.|..:..|.
Zfish   720 LRVS----DSDITENSTEGAGLDIEGVEP------QDEEKR----DGEKIDGDEMQPLGAVEETS 770

  Fly  1245 ESAIKELEQL-QNEKRRALVEHEHSKLSEIDERLKGELREWREQLVPRKQELNRQIKLA------ 1302
            |..::|:..| :|:....|.:    :...||.  :|::.|..|......:..::..|:|
Zfish   771 EQEMREVNVLEENDTEETLTD----QCDVIDS--EGKVEELAESADNVNESADKSPKIADEEQVE 829

  Fly  1303 --IDQHEKRF-GLVTNREEFEDQEVKLPAHLRNIYNERSSRILPRNTFIDPQNMPRSRSSLLMMG 1364
              ||...::. ||..:.|...|.|    ...|.:.:...|.::|..:|   :..|..|..
Zfish   830 DKIDNDLRQVEGLQWDGESESDSE----EEDRGVADGCPSELIPGPSF---ERRPLERDL----- 882

  Fly  1365 GGGNRLSNFRGSAPDLSRSVPNTPIMHKQQRSQMIGDQVLEEDEEQMLSEQMKRA--SVATLPAQ 1427
               :.||.|  ..||....:...|:......|         ...:..|......|  .|.:|.|.
Zfish   883 ---DELSEF--YFPDTLEELEPPPVYIPPSPS---------SSSQPSLPSLFSHAICLVLSLSAA 933

  Fly  1428 NQLRLITQLPANELVKVVTSTPPLNSAEDV 1457
            .|..::|.|..:..:..:..:|||.|...:
Zfish   934 VQPSVLTLLLLSIFLLSLRRSPPLPSLASI 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	111/280 (40%)
		PKK	958..1095	CDD:463600	28/143 (20%)
		PKK	1126..1266	CDD:463600	33/145 (23%)
taok2b	XP_009304676.2	None