Protein Alignment Fatp3 and ACSL1

DIOPT Version :10

• Sequence 1: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_001986.2
• Gene: ACSL1 / 2180
• HGNCID: 3569
• Length: 698
• Species: Homo sapiens
• Alignment Length: 630
• Identity: 125/630 - (19%)
• Similarity: 209/630 - (33%)
• Gaps: 169/630 - (26%)

  Fly   139 LSFAEALEFSQKIAGYFSDRGLERG--DCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGES 201
            ||:.:..|.|:.|......:|.:..  ..:.:..:.|.|:..|..|.....::...:...|..|:
Human   121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEA 185

  Fly   202 LLHSIKVANAKALIVGSELLDVLVSLREKEQLDEVPIYQYTDDEVRGVAGHDLLPG-----AVDL 261
            :.:.:..|         ||..|.|...||.:|           .:.||. :.|:||     .:|.
Human   186 ITYIVNKA---------ELSLVFVDKPEKAKL-----------LLEGVE-NKLIPGLKIIVVMDA 229

  Fly   262 ---------------VTALKTQKKL-----ELPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNL 306
                           ||::|..:.|     ..|....|.:.   .:..:||||||.||.|::|:.
Human   230 YGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKPPAPEDL---AVICFTSGTTGNPKGAMVTHR 291

  Fly   307 RFL-----FMSAGSYYMLKMSSDDVVYDPLPLYHTAGGIV-------GVGNAILNGSTVVLRKKF 359
            ..:     |:.| :...:....||.:...|||.|....:|       |.......|...:|....
Human   292 NIVSDCSAFVKA-TENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDL 355

  Fly   360 SA--------------RNFWLDCDRHNCTVAQYIGELCRYLLATSYSPDQQKHNLR--LMYGNGL 408
            ..              |.|.....:.|.|       |.|:||  .::..:::..||  ::..|.|
Human   356 KVLQPTVFPVVPRLLNRMFDRIFGQANTT-------LKRWLL--DFASKRKEAELRSGIIRNNSL 411

  Fly   409 RPQIWSQFVRRFGIPHIGEIYGATEGNSNLINITNRVGAIGFVPVYGSSL-YPVQVLRCDEYTGE 472
                |.:.:       ..::..:..|...|:       ..|..||..:.| :....|.|..|.|.
Human   412 ----WDRLI-------FHKVQSSLGGRVRLM-------VTGAAPVSATVLTFLRAALGCQFYEGY 458

  Fly   473 LLKDSKGHCIRCQPGQ--AG--------LLVGKVDAR---------------RAVSAFHGYADKG 512
            ...:....|....||.  ||        .|:..||..               :..:.|.||....
Human   459 GQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDP 523

  Fly   513 ASEQKLLRNVFTSGDVFFNSGDMVVRDILGYFYFKDRTGDTFRW-RGENVATQEVEAIITNCVGL 576
            |...:.|     ..|.:.::||:......|.....||....|:. :||.:|.:::|.|......:
Human   524 AKTAEAL-----DKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPV 583

  Fly   577 EDCVVYG---------VQIPHVE---------GKAG----MAAIVDPERKVDMDYLSVVLRGSLP 619
            ....|:|         :.:|.||         |..|    :....|.::.:..|.:.:.....|.
Human   584 AQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLK 648

  Fly   620 PYARPLFIRL------LDEIPRTATFKLKKRELAKEAYDIGQLSD 658
            |:.:...|.|      :|....|.|.|.|:.||..  |...|:.|
Human   649 PFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRN--YFRSQIDD 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:341262	123/623 (20%)
ACSL1	NP_001986.2	LC-FACS_euk	116..694	CDD:341250	125/630 (20%)