Protein Alignment Fatp3 and Acsl3

DIOPT Version :10

• Sequence 1: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_476448.1
• Gene: Acsl3 / 114024
• RGDID: 70552
• Length: 720
• Species: Rattus norvegicus
• Alignment Length: 657
• Identity: 142/657 - (21%)
• Similarity: 239/657 - (36%)
• Gaps: 197/657 - (29%)

  Fly   135 DDRHLSFAEALE-----------FSQKIAGYFS--------DRGLERGD-----------CVALL 169
            |.|.|...|.|.           |.:.|.|:::        .|.|:.|:           .:|:.
  Rat   101 DKRLLGTREILNEEDEIQPNGKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIF 165

  Fly   170 METRLEYPCIWLGLSQ------LGVITALINSNLRGESLLHSIKVANAKALIVGSELLDVLVSLR 228
            .|||.|    |:..:|      ..::|  :.:.|.|.:::|.:.......:|...|||..    :
  Rat   166 CETRAE----WMIAAQACFMYNFQLVT--LYATLGGPAIVHGLNETEVTNIITSKELLQT----K 220

  Fly   229 EKEQLDEVPIYQYT----------DDEVRGVAGHDLLPGAVDLVTALKTQKKLE-------LPSA 276
            .|:.:..||..::.          .:..:||..|.:.     .|.||..:..::       |||.
  Rat   221 LKDIVSLVPRLRHIITVDGKPPTWSEFPKGVIVHTMA-----AVQALGVKADVDKKAHSKPLPSD 280

  Fly   277 VCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYYML-KMSSDDVVYDPLPLYH----- 335
            :.        :.:||||:||:||..:|::...:....|....: ::..:||....|||.|
  Rat   281 IA--------VIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELS 337

  Fly   336 ------TAGGIVGV---------GNAILNGS---TVVLRKKFSARNFWLDCDRHNCTVAQYIGEL 382
                  :.|..:|.         .:.|..||   |.||:....|....: .||....|...:.|:
  Rat   338 AELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEI-MDRIYKNVMNKVNEM 401

  Fly   383 CR-----YLLATSYSPDQQK-------------HNLRLMYGNGLRPQI-----WSQFVRR----- 419
            ..     ::||.:|..:|..             .|:|.:.|..:|..:     .|...:|
  Rat   402 SAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQRFMNIC 466

  Fly   420 FGIPHIGEIYGATE--GNSNLINI----TNRVGAIGFVPVYGSSLYPVQVLRCDEYTGELLK--D 476
            |..| :|:.||.||  |...:..:    |.||||               .|.|.|..   ||  :
  Rat   467 FCCP-VGQGYGLTESTGAGTITEVWDYNTGRVGA---------------PLVCCEIK---LKNWE 512

  Fly   477 SKGHCIRCQPGQAG-LLVGKVDARRAVSAFHGYADKGASEQKLLRNVF--TSGDVFFNSGDMVVR 538
            ..|:....:|...| :|:|      ..:...||.   .:|.|...:.|  .:|..:..:||:...
  Rat   513 EGGYFNTDKPHPRGEILIG------GQNVTMGYY---KNEAKTKADFFEDENGQRWLCTGDIGEF 568

  Fly   539 DILGYFYFKDRTGDTFRWR-GENVATQEVEAIITNCVGLEDCVVY---------GVQIPH----- 588
            |..|.....||..|..:.: ||.|:..:|||.:.|...:::...|         |..:|:
  Rat   569 DPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELT 633

  Fly   589 ----VEGKAGMAAIVDPERKVDMDYLSVV----LRGSLPPYARPLFIRLLDE--IPRTA----TF 639
                .:|..|....:....:::.:.|.|:    :..||..:..||.|||..:  .|.|.    .|
  Rat   634 ELARTKGFNGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAF 698

  Fly   640 KLKKREL 646
            |||::||
  Rat   699 KLKRKEL 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:341262	141/656 (21%)
Acsl3	NP_476448.1	Adenylate forming domain, Class I superfamily	30..717	CDD:473059	142/657 (22%)