|
Fly 14 WNQWILEAISKIRSQKQRPSVQRICQAIGTHHKFHEDIVAEKLEKAVESGAVIKVYNKGLHSYKA 78
:.|||||||.|::.||||||.:|||.|:.:.|......|.|:||.:|:.|.::||.||||:|||.
Rat 9 YTQWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKD 73
Fly 79 PMAKRRVKVDKNTN-----------LYKLVAKAVHDLGECEGSTIKSIENYI--QKFNCIDLSPN 130
|....|:.:.|..| ..||:.:|...|.|..|||:||||.:: || |:|..
Rat 74 PDNPGRIALPKPRNHGKLDNKQSVDWNKLLKRAFEGLAESGGSTLKSIERFLKSQK----DVSAA 134
Fly 131 V------DFKAVIKASIKKAVDAGFLIQEGKLYK--------KGK------------SLTTPRKC 169
. .|...::.:||:||..|.|:::|.||: :|| ||....|.
Rat 135 CGGTAASGFHQQLRLAIKRAVGHGRLLKDGPLYRLNTKAANAEGKEGCESLSCLPPVSLLPHEKD 199
Fly 170 APVSEVVIKGEESCTHCSGNSQKNLNGIPEPLSSCKQCGISLHTTCANIAGRCKSQSYVLLYMLV 234
.||:|.: ..|:.|.|..::|....||.|.||..||.|.|.:|...:.....:
Rat 200 KPVAEPI----PICSFCLGTKEQNREKKPEDLISCADCGNSGHPSCLKFSPELTVR--------- 251
Fly 235 TKGTIWDCQNCADCAVCKMRNR-GPCLLQCFVCKDHFHLTCLDTIPDKKPKHPYRCKTC--SKQG 296
.:...|.|..|..|:.|:.:.: ...:|.|..|...||:.|.|....:.||..:.|:.| .|:|
Rat 252 VRALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKG 316
Fly 297 FDTPKLVKKDNSRIKMEAERMTPSYKYAS---NKRQSIKKDGNIESPSTSKLCVYNDGNGQRRKV 358
.||::|..::||. :||: ..:..:||...:.....||:.. ..|.|::||:
Rat 317 ---RKLLQKKAAQIKR---------RYANPIGRPKNRLKKQSTVSKGPFSKVRT-GPGRGRKRKI 368
Fly 359 PASLSSRKMNHSEDQFEFPSKQKRSQILQGGYLASQETRKRTFSDLSSTSSSSESEDEDDEDDDR 423
::||:..:.||: |||
Rat 369 --TVSSQSASSSEE----------------GYL-------------------------------- 383
Fly 424 NRNGDDNDQDESTSSDSCTSSSSDSDSSESSSDTSEWDDEYDEEEDYDTDRSTIREKNVFESGKQ 488
:.....|.|..||:
Rat 384 ---------ERIDGLDFCRDSSA------------------------------------------ 397
Fly 489 SCAKLSTGDGLGSPQNNELGSENWGFAAVAKNPIDIFVKSKHNSNVKGI--GYSKPAASTFATSP 551
|: |.|...||: |.:| .|..||
Rat 398 --------------------------------PL------KFNKKTKGLIDGLTK----FFTPSP 420
Fly 552 AANRVQKSTPVASSTPEKNSAPIGGMTIKRQTANGQKKKIVPLKSMPLEAGKSYEKCEDDIPYLT 616
:|:|.: |::.:..|
Rat 421 ---------------------------------DGRKAR-----------GEAVDYSE------- 434
Fly 617 EETVMKVQLLEEIERSRET-HSQADGKREMNNDE-DAPGESTKRANPFENQPLPPGVTATDVELY 679
:::.::..|...| |...| |.|. ::..||.:|. |.:|.: :|..|:||:
Rat 435 ------LRIRKKGNRKSSTSHWPTD-----NQDGWESKQESEERL--FGSQEI---MTERDMELF 483
Fly 680 QEVLHKAVVQMSNNHIEKVNDVSLKSGQNTQSPKSIQIGKWDIETWYSSPFPQEYARLLKLFLCE 744
:::..:| ::||. |:.......:.|..|:.||::|.||||||:||||:||.||:|||
Rat 484 RDIQEQA--------LQKVG-VTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCE 539
Fly 745 FCLKYTKSRSVLDRHQNKCIWKQPPGTEIFRQGNISVFEVDGNVNKIYCQNLCLLAKFFLDHKTL 809
|||||.|||::|.:|..||.|..||..||:|:.|||||||||||:.|||||||||||.|||||||
Rat 540 FCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTL 604
Fly 810 YYDVEPFLFYILTKNDQSGCHLVGYFSKEKHCTQKYNVSCILTMPQYQRQGYGRFLIDFSYLLSR 874
||||||||||:||:||..||||||||||||||.||||||||:.:|||||:||||||||||||||:
Rat 605 YYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSK 669
Fly 875 EEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKHRNYTKITFKDIAIKTGLAISDIALAFELLN 939
.|||.|:|||||||||||||.:|||||:||.|| |:|..:|:.|.::..||:...||......|.
Rat 670 REGQAGSPEKPLSDLGRLSYMAYWKSVILECLY-HQNDKQISIKKLSKLTGVCPQDITSTLHHLR 733
Fly 940 FIKLRKNDGDIRYQINVKIEWKKVLAHH-NKMANSKTRIIIEPDCLRWSPLLSVSKLPNII---- 999
.: |.|....|.|..:|::..| .|:..:...:.::|:||||:|:: :.|.:
Rat 734 ML-------DFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI----VSNSVVSEE 787
Fly 1000 -----------------KPISNREYL------SNQMETNSSFKEINEDKISVKQGVSTSSKVNQE 1041
:.:..||.: .|:.:.:||..| :|.|..||: :::||:::::
Rat 788 EDEEADDGEKEEPQGQERELETRERVGKSVSRENKDQDSSSLIE-SEKKPEVKE-LASSSRLSKQ 850
Fly 1042 S---------------SELSTKNR-------GPSSEKLIDERENQRKRAYPEEFLKSASNEAKKP 1084
: .....||| ...|:.|:.|..:..:..|.|...|||::..:..
Rat 851 ALVRDSLPANSQPPRRGRCGRKNRKTQERFGDKDSKMLVGETLSTSQEQYGECEEKSAASRERYT 915
Fly 1085 KL----TAPQPNLE---DQSFGELSDSSDCKSSKDLSEQLTKRAQRLAKRNDLIPHTNKRKHFDR 1142
:: .|||...: |...|..|:|:|.... ||.|..:.|..| :|..|
Rat 916 EVGEQPAAPQAQADGNPDIPKGRFSESADLWRG-----QLKKSPETLKCR---LPEGN------- 965
Fly 1143 PLENNTTSTDHNPPAQSQADTA----GTENGHKSEE-TAAKENCKNVVEKEHVDKPVNIMPKLRG 1202
|..|...:..|.| .:|:..:.|| .:.:.| ..||...|.|:.
Rat 966 ---------DRLPCCYTDGDRAVFRGFSESSEEEEEPESPRSN----------SPPVLTKPTLKR 1011
Fly 1203 KQSNGKRSEEPQFNENPTSDPVAVASLSPAKEITREPVKVAKTESP-----------GKNQESAK 1256
|:....|....:..::..|. |...::|...|:..||.:.:.:|.| .:.:|..:
Rat 1012 KKPILHRRRRVRKRKHHNSS-VVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIEEEEEEEDE 1075
Fly 1257 HDAEP----NSVSDQVLDAVAKKTKKTLFSDVASYNTEDVKYNSEE-------KPMAIAQEPKES 1310
::..| :.:|.|.:......:|:| ||.:.|:.:..|:: ||:::.::...:
Rat 1076 NELFPRGYFHCLSSQDILRCQASSKRT-----ASKDEEEEEEESDDADDTPVLKPVSLLRKCDVN 1135
Fly 1311 PTEAGIKETKPLEVPEQKAKAKSPEKPATVAETVLQHVHAPVNTEKISTEESKLELDVHYLK--- 1372
........:.|::..:...|.|| .|| :|:.|
Rat 1136 SASLEPDTSTPMKKKKGWPKGKS-RKP------------------------------IHWKKRPG 1169
Fly 1373 LSPDSALNPPV--ASVQKPVPEPPAPKEKAKDLQAAQPSEALQKQPEIEMVKKTETKTETPVSNP 1435
..|...||..: .|.|:.:.||..|.:..:..:..:..|.::.:..:...:|.|..||
Rat 1170 RKPGFKLNQDIIAVSTQECIVEPIVPIKPGRKPRTQESEELVEVKEGLVEERKEEMHTE------ 1228
Fly 1436 PSNRTDVSSLVEQPVKAAPEKVEQPMVKEAVDIKDKALKKPV-----PDVPVVKPEATSCEKK-I 1494
|.|:.|:.....:.||: ...|: ||....:|||...|:| :
Rat 1229 -----------------ADEEAEEEEDAASSDIR---AMSPLDSSNSPDADPKEPEAEEEEEKPL 1273
Fly 1495 DHSKTKVFHEKEAIKTDQQLVQVKEEEKSNARAPSAPIPIRDKIQLKGNEHAQLQ---------N 1550
|..:.. |:| .|:|.:.::||: |::..:.|::.... :
Rat 1274 DDPRQS---EEE----PQELEEQEQEEE-------------DEVTAEANQNEDHDADDEDDGHLD 1318
Fly 1551 SIPSQFPLNQMPNYHTSQYWQWEYYGYNLSHLDASQKGQKQFHKDLATTMAYTH----NFTQNLY 1611
|:.::.|..|......: |..|...|.||||.:..::..||...|.|.:. :...::.
Rat 1319 SLKTKEPEGQPAREDGT-----EEPGTQESFLDASIQDSRENAKDKDETEADSEEEQPSHEASVG 1378
Fly 1612 QSANLAMQHAHHQMHQTKE-----KHKVERKNSGKKEEQNKVVSSVNVVSTAREDAHVQHCNEYA 1671
.......:..|.:...||| |.:.|..:|....|..:.|.|:....::..:...|.|.|..
Rat 1379 SETMPGSEEDHEEDSNTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETL 1443
Fly 1672 ANNQAALYNQKCASQQKQAQQMKSLANVQNPVPRQSNSNAPESTVLMPNPVISQAGSVPAKQKVE 1736
|..| .|.:.....:..|...::.....::..|..|..:.|..:| ::.|.|:...:|
Rat 1444 AACQ-TLQSYTHTDEDPQMSMVEDCHASEHNSPISSIPSHPSQSV--------RSVSSPSMPALE 1499
Fly 1737 HGVNSTSVISREGKLNKIGHSN--------IHATAQHANLQVGGGQSDV----NPNMVYNTESSA 1789
.|. |.:...:|.|:.....| :.:.:.|:...|..|.||: :....|...||.
Rat 1500 SGY--TQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSY 1562
Fly 1790 NSAMQHYDCGISAQINMDSPANIGSAIAHGPQEISATSNVHMHQPHRQFSDCSMQNQPVTTPMHM 1854
:|.|....|| |..|. |:.::| .:|::|:: .||..|.|....
Rat 1563 DSTMGSSICG-----NNSSQ----SSCSYG--GLSSSSSL-------------TQNSCVVTQQMA 1603
Fly 1855 SIQNS-HMQQQNNLNLNLAPEGSSNINLLSNPQHQHQSRKLNAQADIAVSSPTPSHRATTPKQIR 1918
|:.|| .|.|||:: :.::|.|:.| ||.....|..:.| .|.|......|.|..
Rat 1604 SMGNSCSMLQQNSV------QPATNCNIKS-PQTCVVERPPSNQ------QPPPPPPPPPPPQQP 1655
Fly 1919 SGNTQQRDAKNAAPPTTTTNTHHQIPQGGAAANISKSHHDSLHNLQFSQHGHQQNMQPIDYVPIP 1983
....||:.|....||. || ||...|....|.|
Rat 1656 QPQPQQQAAPQPPPPQ---------PQ-------------------------QQPPPPPQQQPQP 1686
Fly 1984 QISQNFSANPSNYDIVGMPAVIQQRMSLNGSVHSLANSHQRIEQPSSACAVNNFYLQNNMPAAEN 2048
|...|| :.|.|.|::| |:..||..
Rat 1687 ------------------PPPPQQ------------------QPPLSQCSMN-----NSFTAAPM 1710
Fly 2049 APRVPVSSSLGGPPTAGNND--QRQAGQDSITTANSSGATASLAGNLCSLSKLQQLTNCL----- 2106
...:|.| || .||.. :|..|.....:.:...||.||| |||||||.:
Rat 1711 IMEIPES---GG---TGNISIYERIPGDFGAGSYSQPSATFSLA-------KLQQLTNTIMDPHA 1762
Fly 2107 ---ESQPCNTSPGAQVNLAP------SPHHPI--PPNS----TPPPHLLMQNRNISTP---PNML 2153
...|..||....|:|:. :|.||: .|.: ||||:|.....|:::| .||.
Rat 1763 MPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLAPTTMNLTSPLLQCNMS 1827
Fly 2154 QTQVTPLQYKYYPGNMNIP------------PITSAQNTSRNTRNTPSAPVQHTSTPMGSGNNRT 2206
.|.:.....:...|.|.:. |..:|.......|:.|:..:|.....:.......
Rat 1828 ATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSATAHQQQLYGRSPPAVAMQAGPRALAVQRGMN 1892
Fly 2207 ANVHISP----NL----MAPYGAINSYRMSPQQSPPTGSYSSGGDYPN--SQIPMQMM--NMQSQ 2259
..|::.| |: |....|:|||||: |.....||.|...|.| :|.||||. .|.||
Rat 1893 MGVNLMPTPAYNVNSMNMNTLNAMNSYRMT--QPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQ 1955
Fly 2260 YQDACVLQRGTPSNPMY--PTYSPYL--------PLNGSIRR 2291
......:|.....|.|| |::..|: .|||...|
Rat 1956 AYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMR 1997
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