Protein Alignment enok and mys-4

DIOPT Version :10

• Sequence 1: NP_523838.1
• Gene: enok / 37859
• FlyBaseID: FBgn0034975
• Length: 2291
• Species: Drosophila melanogaster
• Sequence 2: NP_492265.1
• Gene: mys-4 / 183194
• WormBaseID: WBGene00007914
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 757
• Identity: 205/757 - (27%)
• Similarity: 313/757 - (41%)
• Gaps: 207/757 - (27%)

  Fly   296 GFDTPKLVKKDNS----------RIKMEAERMTPSYKYASNKRQSIKKDGNIESPSTSKLCVYND 350
            |.::.|...|.||          :.::..::.|||  .:|:||::::|....::||:|:
 Worm     2 GKNSTKPTSKANSSPEGKAMSPMKTQLLDDQQTPS--SSSSKRKNLRKPSTDDTPSSSE------ 58

  Fly   351 GNGQRRKVPASLSSRKMNHSEDQFEFPSKQKRSQILQGGYLASQETRKRTFSDLSSTSSSSESED 415
                    |.|..:| ::.:|...|..::::|:  |:.|.:|           |...|...|.:.
 Worm    59 --------PLSKKNR-LDSTETAEEDNTRRRRT--LKHGEVA-----------LPVCSFCKEDQK 101

  Fly   416 EDDEDDDRNRNGDDNDQDESTSSDSCTSSSSDSDSSESSSDTSEWDDEYDEEEDYDTDRSTIREK 480
            .||                                 |...:.||...:|.       .|..:|.|
 Worm   102 ADD---------------------------------EPLKECSECKAKYH-------IRKCLRYK 126

  Fly   481 -----NVFESGKQSCAKLSTGDG----LGSPQNNEL--------GS-------------ENWGFA 515
                 |:.:..|..|.:....|.    :|.|.|.|.        ||             .:|...
 Worm   127 EEFATNILKLNKWFCPRCVECDSCKGYIGDPSNIECTFCCRAWHGSCAPKGYSPSGEFDSDWYCI 191

  Fly   516 AVAKNPIDIFVKSKHNSNVKGIGYSKPAASTFATSPAANRVQKSTPVASSTPEKNSAPIGGMTIK 580
            |..:              ||||       ..:.|:..::|...|.||.....::     ||...|
 Worm   192 ACCR--------------VKGI-------KIWHTTSISHRSHPSAPVKERKTKR-----GGAARK 230

  Fly   581 RQTA-NGQ--------KKKIVPLKSMPLEAGKSYEKCEDDIPYLTEETVMKVQLLEEIERSRETH 636
            .:.. .|.        .|:.:..:.:..|||.|.:|   .:||.
 Worm   231 DELEFEGDIDELKDLLAKRDLTFEILNYEAGFSSKK---PLPYT--------------------- 271

  Fly   637 SQADGKREMNNDEDAPGESTKRANPFENQPLPPGVTATDVELYQEVLHKAVVQ--MSNNHIEKVN 699
            ..:.||:.....:.:|.......:..|..|..|.|...|:||::....:|..|  :.|.|.|
 Worm   272 PTSSGKKNKKKQQKSPVREEFDYSNAERSPDFPKVVRADLELFKATKSEAYQQTPIFNPHPE--- 333

  Fly   700 DVSLKSGQ-----NTQSPKSIQIGKWDIETWYSSPFPQEYARLLKLFLCEFCLKYTKSRSVLDRH 759
                  ||     ..::.|:|          |||.:.:.......|:.|:|||..|..:..|..|
 Worm   334 ------GQFLHFGTGKACKAI----------YSSAYEEPLHSSAHLYACKFCLHTTNLKEDLIVH 382

  Fly   760 QNKCIWKQPPGTEIFRQGNISVFEVDGNVNKIYCQNLCLLAKFFLDHKTLYYDVEPFLFYILTKN 824
            .:.|..|.||||||:|...::.|||||.|.|.|||:|||::|.|:..||||.:||.|.||:|.:.
 Worm   383 WDICNAKHPPGTEIYRNDGLAFFEVDGAVQKKYCQDLCLISKLFIASKTLYDEVETFKFYVLCEI 447

  Fly   825 DQSGCHLVGYFSKEKHCTQKYNVSCILTMPQYQRQGYGRFLIDFSYLLSREEGQLGTPEKPLSDL 889
            ...|..:||||||||:.::..|:||:|.:|..|:.||||.|||.||.|||.|.::|.||.|||||
 Worm   448 TTEGYVIVGYFSKEKNPSKNNNLSCLLVLPMVQKMGYGRLLIDMSYELSRLEMRIGHPEHPLSDL 512

  Fly   890 GRLSYFSYWKSVVLEYLYKHRNYTKITFKDIAIKTGLAISDIALAFELLNFIKLRKNDGDIRYQI 954
            |.|:|..||:|.:|.|:.:||||.::..||:.:.|.:|..||.....|.|.|.|:   |.: |.|
 Worm   513 GILAYRGYWRSSLLCYIREHRNYDRLNIKDMCLATRIAPVDIVNQLMLDNMIVLK---GGV-YSI 573

  Fly   955 NVKIEWKKVLAHHNKMANSK-TRIIIEPDCLRWSPLLSVSKL 995
            .:   .|:.|    |...|: .|..::|..|.|.|..|..:|
 Worm   574 KI---GKRAL----KFPLSQCRRRFVDPSQLFWKPKPSAERL 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
enok	NP_523838.1	PHD_SF	183..>215	CDD:473978
		PHD	248..292	CDD:214584
		PLN00104	<714..989	CDD:215056	115/275 (42%)
		PspC_subgroup_1	<1171..>1440	CDD:468201
		PRK10263	<1206..>1736	CDD:236669
mys-4	NP_492265.1	PLN00058	35..117	CDD:177689	26/144 (18%)
		PHD	92..144	CDD:214584	14/91 (15%)
		PHD	147..193	CDD:214584	8/45 (18%)
		MOZ_SAS	391..565	CDD:460362	88/173 (51%)