Protein Alignment enok and KAT5

DIOPT Version :10

• Sequence 1: NP_523838.1
• Gene: enok / 37859
• FlyBaseID: FBgn0034975
• Length: 2291
• Species: Drosophila melanogaster
• Sequence 2: NP_874369.1
• Gene: KAT5 / 10524
• HGNCID: 5275
• Length: 546
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 186/547 - (34%)
• Similarity: 257/547 - (46%)
• Gaps: 117/547 - (21%)

  Fly   462 DEYDEEEDYDTDRSTIREKNVFESGKQSCAKLSTGDGL-----GSPQNNELGSENWGFAAVAKNP 521
            ||:...|..|..:....:|.         ||..|.:||     |||: .|:.:...........|
Human    88 DEWVTHERLDLKKIQFPKKE---------AKTPTKNGLPGSRPGSPE-REVPASAQASGKTLPIP 142

  Fly   522 IDI---FVKSKHNSNVKGIGYSKPAASTFATSP---AANR----VQKSTPVASSTPEKNSAPIGG 576
            :.|   |...|....:.|....:|.:|:....|   :..|    |..:|||.|.|...:..|..|
Human   143 VQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNG 207

  Fly   577 MTIKRQTAN-GQKKKIVPLKSMPLEAGKSYEKCEDDIPYLTEETVMKVQLLEEIERSRETHSQAD 640
            ...:...|. |:|:|               ..|
Human   208 AARRAVAAQPGRKRK---------------SNC-------------------------------- 225

  Fly   641 GKREMNNDEDAPGESTKRANPFENQPLPPGVTATDVELYQEVLHKAVVQMSNNHIEKVNDVSLKS 705
                :..|||:...|       :..|..|.:|.:   |..:..|..:|....| ||
Human   226 ----LGTDEDSQDSS-------DGIPSAPRMTGS---LVSDRSHDDIVTRMKN-IE--------- 266

  Fly   706 GQNTQSPKSIQIGKWDIETWYSSPFPQEYARLLKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPG 770
                    .|::|:..::.||.||:|||...|..|:||||||||.:|...|.||..||..:.|||
Human   267 --------CIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPG 323

  Fly   771 TEIFRQGNISVFEVDGNVNKIYCQNLCLLAKFFLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYF 835
            .||:|:|.||.||:||..||.|.||||||||.||||||||||.:|||||::|:.|..|.|:||||
Human   324 NEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYF 388

  Fly   836 SKEKHCTQKYNVSCILTMPQYQRQGYGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKS 900
            ||||..|:.|||:||||:|.|||:|||:.||:|||.||:.||:.|||||||||||.|||.|||..
Human   389 SKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ 453

  Fly   901 VVLEYLYKHRNYT----KITFKDIAIKTGLAISDIALAFELLNFIKLRKNDGDIRYQINVKIEWK 961
            .:||.|...::.:    :||..:|:..|.:...|:....:.||.|...|.    :|.:.:.   :
Human   454 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKG----QYILTLS---E 511

  Fly   962 KVLAHHNKMANSKTRIIIEPDCLRWSP 988
            .::..|.: |..|..:.|:..||.::|
Human   512 DIVDGHER-AMLKRLLRIDSKCLHFTP 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
enok	NP_523838.1	PHD_SF	183..>215	CDD:473978
		PHD	248..292	CDD:214584
		PLN00104	<714..989	CDD:215056	137/279 (49%)
		PspC_subgroup_1	<1171..>1440	CDD:468201
		PRK10263	<1206..>1736	CDD:236669
KAT5	NP_874369.1	Tudor-knot	40..98	CDD:432022	3/9 (33%)
		PLN00104	76..537	CDD:215056	185/545 (34%)