DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment: CG3121 and RSPH4A

Sequence 1:NP_611869.1 Gene:CG3121 FlyBaseID:FBgn0034957 Length:708 Species:Drosophila melanogaster
Sequence 2:NP_001010892.1 Gene:RSPH4A HGNCID:21558 Length:716 Species:Homo sapiens

Alignment Length:758 Identity:228/759 (30%)
Similarity:340/759 (45%) Gaps:196/759 (26%)


  Fly    13 STSSSHFAP-------PP------VCAPRRKKPEKPAAEEASPECSNV---TSSSSSSTTTIS-- 59
            |:|.|..||       ||      ...|....|.....|::|.:..:.   ||.|..:|...|  
Human    91 SSSPSPLAPARQDLAAPPQSDRTTSVIPEAGTPYPDPLEQSSDKRESTPHHTSQSEGNTFQQSQQ 155

  Fly    60 -----IGAFDSQCNLHNARNPEA---------PNIGYELNV-------------------AKSIL 91
                 .|..|...|  ||:..|.         .|..|:|..                   ||:.|
Human   156 PKPHLCGRRDVSYN--NAKQKELRFDVFQEEDSNSDYDLQQPAPGGSEVAPSMLEITIQNAKAYL 218

  Fly    92 QKYSTLSGDNLFDHLSDIIKRVIDERPPNVIDFFEEFSRNVREQKFHLPERFPPSGVFDEVR--- 153
            .|.|:.||.||:||||:::.::::|||.|.:|.||..|::|:...|        |..||.::   
Human   219 LKTSSNSGFNLYDHLSNMLTKILNERPENAVDIFENISQDVKMAHF--------SKKFDALQNEN 275

  Fly   154 ----SFRVAKKILQSMKLPYVVEGEDLMGEDLSVEDLRTNEDMRIVIDDSMRYFVTFNERVQQLQ 214
                ::.:|:| .:::.|...:||.|...||...|:...|                    |.:..
Human   276 ELLPTYEIAEK-QKALFLQGHLEGVDQELEDEIAENALPN--------------------VMESA 319

  Fly   215 FYWTQCGFSISNDDIFQLASAMNRL-QTHPSIMQCRFWGCINGLKASYYIVEASLTREEIASRLV 278
            ||:.|.|..:..|:.:::..|:.:| .||| |.:|||||.|.||:.:|.:.|......|      
Human   320 FYFEQAGVGLGTDETYRIFLALKQLTDTHP-IQRCRFWGKILGLEMNYIVAEVEFREGE------ 377

  Fly   279 MMEEEMRQKQIPFPMRKDREDKPPPAHIGPELTPGIYGWEEFPPEELEKMKPKAAPVPLVEEMEL 343
             .|||:.::.:    .::|::....||             |...:||.|...||...        
Human   378 -DEEEVEEEDV----AEERDNGESEAH-------------EDEEDELPKSFYKAPQA-------- 416

  Fly   344 YDIPPEFIGKGCNRYSYFVVNSLFDDWIELPIVTPRQIVVSRQIKKFLTGDLEADVISYPCFPGK 408
              ||.|....|.|:|.|||.|.....|::||.|.|.|||::|:||||.||.|:|.:||||.|||.
Human   417 --IPKEESRTGANKYVYFVCNEPGRPWVKLPPVIPAQIVIARKIKKFFTGRLDAPIISYPPFPGN 479

  Fly   409 EKHYLRTLIGRITAGTYIAPVGYYRRMTKKEQRMFDGEEEEEGEEEEEEEEEEEFNEGEEEQIED 473
            |.:|||..|.||:|||:::|:|:|                :.||||.|||||.   ||.....|:
Human   480 ESNYLRAQIARISAGTHVSPLGFY----------------QFGEEEGEEEEEA---EGGRNSFEE 525

  Fly   474 NDVMLLKNEKYEAEPLGSLATPVA-WVHVRSNILNQQGRVVWYDEEKARKEREKALALYLKMQML 537
                   |..:|...:..|...:: |||...:||: |||..|::..                   
Human   526 -------NPDFEGIQVIDLVESLSNWVHHVQHILS-QGRCNWFNSI------------------- 563

  Fly   538 GEMEEEVEEEEDEEEGEEEGEEEGMIEGFNQPELGPSILSSCANDMNPEVPVSWLARMTSKYTNQ 602
             :..||.|||||||:.:.:         :.:.|:|..:|:..:.|:..:....|..|::|....|
Human   564 -QKNEEEEEEEDEEKDDSD---------YIEQEVGLPLLTPISEDLEIQNIPPWTTRLSSNLIPQ 618

  Fly   603 KERMLVMQSNVWPGAYTFIFEKTCESIYLGWGHKY----YARNIPFKHLPMVQEEFPHNPEDFVE 663
             ..:.|:|||:|||||.|...|..|:.|:||||||    |...:|    |.|.:|:|..|| ..|
Human   619 -YAIAVLQSNLWPGAYAFSNGKKFENFYIGWGHKYSPDNYTPPVP----PPVYQEYPSGPE-ITE 677

  Fly   664 ANDPTVEEEEAYKAWLLRKQQKAEYVAEDIEDYDDDEFADQYD 706
            .:||:||||:|::|    .|:.....||:.|..:|::..|.||
Human   678 MDDPSVEEEQAFRA----AQEAVLLAAENEESEEDEDEEDDYD 716

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG3121NP_611869.1 Radial_spoke 83..679 CDD:282555 196/628 (31%)
RSPH4ANP_001010892.1 Radial_spoke 211..693 CDD:282555 195/612 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C356383687
eggNOG 1 0.900 E1_28KDA
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 271 1.000 Inparanoid score I2957
Isobase 00.000 Not matched by this tool.
OMA 1 1.010
OrthoDB 1 1.010 D166599at33208
OrthoFinder 1 1.000 FOG0003149
OrthoInspector 1 1.000 T610287
orthoMCL 1 0.900 OOG5_129136
Panther 1 1.100 LDO PTHR13159
Phylome 1 0.910 0.800 Consistency score
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R6491
TreeFam 1 0.960
User_Submission 00.000 Not matched by this tool.
1211.800

Return to query results.
Submit another query.