Protein Alignment Pask and Pask

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_001009362.1
• Gene: Pask / 301617
• RGDID: 1306146
• Length: 1385
• Species: Rattus norvegicus
• Alignment Length: 1315
• Identity: 343/1315 - (26%)
• Similarity: 503/1315 - (38%)
• Gaps: 488/1315 - (37%)

  Fly    15 LSSSNAQCSRNRCAND----DPIMGSHSQSRQNSSGMLNMMD--ASSFSMPPPNLHSSKVINPNK 73
            |::.|...|:..||..    |||.|.     ..|:...:::.  ||..|.|   |.|:.|.||||
  Rat    72 LAAQNICTSKLHCAATPDYADPIAGP-----LGSTSCCSLLRGLASGCSGP---LLSTPVCNPNK 128

  Fly    74 AIFTIDANTGQIFIVNNKACQLLGYTSQELRNKGFFDLLNGKTESHISSLAEMQIEGDEGRVVLL 138
            |:||:||.|.:|.:.|:|||.||||:|.:|..:.............:.:|:|..:|.| |...::
  Rat   129 AVFTVDAKTTEILVANDKACSLLGYSSHDLIGQKLTQFFLKSDSEVVEALSEEHVEAD-GHAAVV 192

  Fly   139 SGKVIEMKTKSGGKILVSLWIRQISSDGR--HIAVAEPVERHICHISTDRSGVITSVDSTTATIF 201
            .|.|:::.::||.||.||:||:::..|..  .:.|.|||||....::....|.|||.||..|.:.
  Rat   193 FGTVVDIVSRSGEKIPVSVWIKRLQQDRGLCCVVVLEPVERVSAWVAFQSDGTITSCDSLFAHLH 257

  Fly   202 FYESVESVVGVSIVTLIPFIKLPDPDSREIPKSLRKQRATGRTTDNVKFPLCL---------LIA 257
            .:.|.:.|||..::.|||.|:|| |..:.:||||:.||:.||..|...|||.|         .:|
  Rat   258 GFTSPKDVVGQCVIDLIPSIQLP-PPGQHVPKSLKIQRSVGRARDGTTFPLSLKLKSKTSGKAVA 321

  Fly   258 LDEDASAGYSHSGKTGLNITVWVFQNLSGLIVVDDIGNILMCNQPFSLLMFGYGQDKIMNMHISA 322
            ..|.||       :.|...:||||..:||||.:...|.|...|..|:|::||||:.:::..:|:.
  Rat   322 ESEVAS-------EPGYQASVWVFCTISGLITLLPDGTIYGINHSFALMLFGYGKTELLGKNITC 379

  Fly   323 ILPNF------GKDSREEKSPNVSN-------------TSITSNDWE------------------ 350
            ::|.|      ..|| ..:.|::.|             :|....|||
  Rat   380 LIPGFYHCMDLAYDS-SVQLPDLVNCLDIGSKSGPGEMSSDAKQDWELASGAQDPRIDVLTRGHM 443

  Fly   351 ----------------------------------------------------------------- 350
                                                                             
  Rat   444 PSQDETLKLRGGQVSPRTQTQLETGRHILPSCASQPSLGVDSSPVDGERSLPTDQRNVPKRNLLA 508

  Fly   351 ----------PDT---DPLVVDNDSSLQ------------------------------------- 365
                      |||   .|.|:...|.:|
  Rat   509 HAEQLLSQTQPDTLEISPPVLKELSEIQKNISEESPLTHRKWLLSKAQKDTTKGSLPIHDEKLLL 573

  Fly   366 --------------------------------------SCK--------KSSTNRT--------- 375
                                                  ||:        |..:||.
  Rat   574 ASQHIHVLGKENPSAAESYREGLLAESRSKPVDAKPFASCEDSELLVPAKDRSNRADMSSLQQEA 638

  Fly   376 -----------APNN-EQSSVGDAHLSCNLENSSGLFC--------------------------- 401
                       :||. ..:::.:.|.:..:...|..:|
  Rat   639 QLELMGISSPGSPNPWADATMPEPHTTGQIPGGSLTYCPQHRSEWILQQRGQDSAPSPSAMGCVF 703

  Fly   402 ---------------DLRQPDDCTIDDILT---------------------PVNASNSF------ 424
                           |..:...|.|.:.|:                     |..|..||
  Rat   704 VGTPTLDEPWPGVRNDREELQTCLIKEQLSKSSFGGALGISCVELVPAEHPPFTAPVSFCDWGGR 768

  Fly   425 ---------------------------PADEFEVGSQS--------------------------- 435
                                       .|.|.:|.|.|
  Rat   769 DLHASRSGSSSACYALATDLPGVLEAVEAQEADVSSYSWNLRELFLNDRTDRTPSHCSCTTSELS 833

  Fly   436 --------------------------------------------------------QVNESSLDK 444
                                                                    :::..||..
  Rat   834 ETPSLSGVGSDLDVGILHRQTSDILAHREMLLLSGTYFDLREGHRFQEMGAGHDGAELSNISLVS 898

  Fly   445 AKSASTETCDASGSNP---------------ATRLLSSI-----------------NGSFVGEAI 477
            ::...|...::.|.:|               ..||.:.|                 .|.|.|...
  Rat   899 SEHYETSDIESLGCDPPIPDPGPNNMCLSAEKPRLSAQITSTPVAPGPTSLQQEIQEGIFSGSCY 963

  Fly   478 HADGSVIEVVYSVLLQILPCSNRVYCIWVC-------RNPSTRLDGEKYNYANLTSTFNSMASTV 535
            |.||..:.|.:.|....|..|..::|.|:.       |:.:||   .:...|:|.|:.:||....
  Rat   964 HRDGLRLSVQFEVKRVQLQGSATLFCCWLVKDFLHSHRDSATR---TRLFLASLPSSTHSMPDLS 1025

  Fly   536 EQSLGQVIKTTA-AQNSSRPNSLSLVSKYEDELYLGDYSKYYTSIRQIGRGAYGYVNMAFRNSDR 599
            ..|.|::::... .:.|..|..|..::..|     |:||..|.::|.:|.||:|:|..|......
  Rat  1026 GSSFGEMLRAKPWFEESPTPAELEGLAACE-----GEYSHKYNTLRPLGSGAFGFVWTAVEKEGN 1085

  Fly   600 LLVITKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTLNHKNIVSVLDVFENDLFYQLVMEKHGSG 664
            ..|:.|||.|||:.....|:......||:||.:|..:.|.||:.::|||||..|:||||||||||
  Rat  1086 KEVVVKFIKKEKVLEDCWVEDPKLGRVPLEISILSKVEHANIIKIVDVFENQGFFQLVMEKHGSG 1150

  Fly   665 MDLWTFIERRPLMDEKLGSYIFRQVADAVNYLHEQKILHRDIKDENIIIDQNFTIKLIDFGSATF 729
            :||:.||:|.|.:||.|.||||||:..||.||..|.|:|||||||||:|.::|||||||||||.:
  Rat  1151 LDLFAFIDRHPCLDEPLASYIFRQLVSAVRYLRSQGIIHRDIKDENIVIAEDFTIKLIDFGSAAY 1215

  Fly   730 MEEGKFFSTFYGTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLMFFENPFIDVEETLKAEIQIP 794
            :|:||.|.||.||.|||:||||.||.|.|||||:|:||||||.|:|.||||.:||||::|.|..|
  Rat  1216 LEKGKLFYTFCGTIEYCAPEVLIGNPYRGPELEMWSLGVTLYTLIFEENPFCEVEETMEAVIHPP 1280

  Fly   795 KAVSEQLSRLLSSMLNKDPKYRCTMHQLITDPWLTQEVNPSTFSFSWIVPCKAHEANPNLYFSGY 859
            ..||::|..|||.:|...|:.|.|:.:||.|||:||.||..  :::|...|:..:..     ||.
  Rat  1281 FLVSQELMSLLSGLLQPCPEQRTTLEKLIVDPWVTQPVNLD--NYTWEEVCRTSQPE-----SGL 1338

  Fly   860 LYSSTSVLSTISPQE 874
            :.:::..|::.||.|
  Rat  1339 MSAASLELASRSPSE 1353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914	37/102 (36%)
		PAS	182..350	CDD:441804	62/195 (32%)
		PAS	286..>325	CDD:238075	13/38 (34%)
		STKc_PASK	575..828	CDD:270906	139/252 (55%)
Pask	NP_001009362.1	PAS	129..228	CDD:238075	35/100 (35%)
		PAS	340..392	CDD:214512	18/57 (32%)
		STKc_PASK	1061..1314	CDD:270906