Protein Alignment Pask and par-1

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Alignment Length: 623
• Identity: 155/623 - (24%)
• Similarity: 257/623 - (41%)
• Gaps: 144/623 - (23%)

  Fly   329 KDSREEKSPNVSNTSITSNDWEPDTDPLVVDNDSSLQSCKKSSTNRTAPNNEQSSVGDAHLSCNL 393
            :..::::..:.:|.:|.|  ..|.|.|  |.|.:::.....||.:.|:
  Fly    72 QQQQQQQQHDSANANIVS--LPPTTTP--VANTNTMMPIVTSSNSATS----------------- 115

  Fly   394 ENSSGLFCDLRQPDDCTIDDILTPVNASNSFPADEFEVGSQSQ----VNESSLDK---------- 444
             ||:.                .||..||.:  |....|||.||    |:.|:.:.
  Fly   116 -NSTA----------------ATPTPASGA--AATGGVGSVSQGPATVSASAANTNHSHQHSHQH 161

  Fly   445 ----AKSASTETCDASGSNPATRLLSSINGSFVGEAIHADGSVIEVVYSVLLQILPCSNRVYCIW 505
                |.:.:|:....|.:|.|....|:||    ....|..||          .:.|..|:
  Fly   162 HHHVANNMTTDGARLSSNNSAVVASSAIN----HHHHHTPGS----------GVAPTVNK----- 207

  Fly   506 VCRNPSTRLDGEKYNYANLTSTFNSMASTVEQSLGQVIKTTAAQNSSRPN----SLSLVSKYEDE 566
                             |:.||.::..|.::|      :|::|:.|  ||    |.:.:.....|
  Fly   208 -----------------NVLSTHSAHPSAIKQ------RTSSAKGS--PNMQMRSSAPMRWRATE 247

  Fly   567 LYLGDYSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVPIEIH 631
            .::|.|.    .|:.||:|.:..|.:|........|..|.|.|.:|      .....:::..|:.
  Fly   248 EHIGKYK----LIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQL------NPGSLQKLFREVR 302

  Fly   632 LLQTLNHKNIVSVLDVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQVADAVNYL 696
            :::.|:|.|||.:..|.|.:....|:|| :.||.:::.::.....|.||.....|||:..||.|.
  Fly   303 IMKMLDHPNIVKLFQVIETEKTLYLIME-YASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYC 366

  Fly   697 HEQKILHRDIKDENIIIDQNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGNRYVGPEL 761
            |:::|:|||:|.||:::|....||:.|||.:.....|....||.|:..|.:||:..|.:|.|||:
  Fly   367 HQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEV 431

  Fly   762 EIWALGVTLYVLMFFENPFIDV------EETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRCTMH 820
            ::|:|||.||.|:....||...      |..|:.:.:||..:|.....||...|..:|..|.::.
  Fly   432 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLE 496

  Fly   821 QLITDPWLT-----QEVNPSTFSFSWIVPCKAHEANPN----LYFSGYLYSSTSV-LSTISPQES 875
            .::.|.|:.     .|:.|      :|.| ||..|:|.    |...||..|.... ||.:...:.
  Fly   497 TIMGDKWMNMGFEEDELKP------YIEP-KADLADPKRIEALVAMGYNRSEIEASLSQVRYDDV 554

  Fly   876 FSHI----EESSIGGSDDARLASHRTGHKLCVNEAKHN 909
            |:..    .:|:...||.:|..|..:...:..|:|..|
  Fly   555 FATYLLLGRKSTDPESDGSRSGSSLSLRNISGNDAGAN 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914
		PAS	182..350	CDD:441804	3/20 (15%)
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	79/258 (31%)
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	80/262 (31%)
		UBA_MARK_Par1	525..563	CDD:270522	8/37 (22%)
		MARK1-3_C	839..936	CDD:213381