Protein Alignment Pask and Pask

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_543126.2
• Gene: Pask / 269224
• MGIID: 2155936
• Length: 1383
• Species: Mus musculus
• Alignment Length: 1311
• Identity: 339/1311 - (25%)
• Similarity: 496/1311 - (37%)
• Gaps: 493/1311 - (37%)

  Fly     6 DVTDQAAGKLSSSNAQCSRNRCANDDPIMGSHSQSRQNSSGMLNMMDASSFSMPPPNLHSSKVIN 70
            :..|..||.|.|::. ||..|                   |:.:....|..|.|        |.|
Mouse    91 EYADPTAGPLGSTSC-CSLLR-------------------GLASGCSGSLLSTP--------VCN 127

  Fly    71 PNKAIFTIDANTGQIFIVNNKACQLLGYTSQELRNKGFFDLLNGKTESHISSLAEMQIEGDEGRV 135
            ||||:||:||.|.:|.:.|:|||.||||:|.:|..:.............:.:|:|..:|.| |..
Mouse   128 PNKAVFTVDAKTTEILVANDKACSLLGYSSHDLIGQKLAQFFLKSDSEVVEALSEEHVEAD-GHA 191

  Fly   136 VLLSGKVIEMKTKSGGKILVSLWIRQISSDGR--HIAVAEPVERHICHISTDRSGVITSVDSTTA 198
            .::.|.|:::.::.|.||.||:||:::..|..  .:.|.|||||....::....|.|||.||..|
Mouse   192 AVVFGTVVDIVSRIGEKIPVSVWIKRLQQDRGLCCVVVLEPVERVSAWVAFQSDGTITSCDSLFA 256

  Fly   199 TIFFYESVESVVGVSIVTLIPFIKLPDPDSREIPKSLRKQRATGRTTDNVKFPLCLLI------- 256
            .:..:.|.:.|||..::.|||.::|| |..:.|||||:.||:.||..|...|||.|.:
Mouse   257 HLHGFTSPKDVVGQCVIDLIPSMQLP-PPGQHIPKSLKIQRSVGRARDGTTFPLSLKLKSKPSGR 320

  Fly   257 -ALDEDASAGYSHSGKTGLNITVWVFQNLSGLIVVDDIGNILMCNQPFSLLMFGYGQDKIMNMHI 320
             ..|.:|::      :.|...:||||..:||||.:...|.|...|..|:|::||||:.:::..:|
Mouse   321 AVADSEAAS------EPGYQASVWVFCTISGLITLLPDGTIYGVNHSFALMLFGYGKTELLGKNI 379

  Fly   321 SAILPNF---------------------------------------------------------- 327
            :.::|.|
Mouse   380 TFLIPGFYHYMDLTYDSSVQLPDLVNCLDIGRKSGPGEMNSDAQHNWELASGAQGPRIDVVLARD 444

  Fly   328 ----------------------------------------GKDSREEK----------------- 335
                                                    |.||..|.
Mouse   445 HMPSQDETLKLVGGQVSSRTQTRLETGYKILPSSACQPSLGVDSNPEDGEQSLLTDQQSIPKRNL 509

  Fly   336 ---------------------------SPNVSNTS-ITSNDW----------------------- 349
                                       ..|:|..| :|...|
Mouse   510 PAHGGQNQLDTSEISLPVLKEHLLSEIQKNISEESPLTHRKWLSKVQQNPTKGSLPIHEEQLLFA 574

  Fly   350 ----------EP----------------------------DTDPL--VVDNDSSLQSCK------ 368
                      :|                            |::||  |.|..||:.:|.
Mouse   575 GQHIHVLGKEDPSAAESYRESLLEESKSKPVDAKLFASCEDSEPLVSVKDRGSSVDTCNLHQEAQ 639

  Fly   369 -----KSSTN----RTAP---------------------------NNEQSSVGDAHLSCNL---- 393
                 .||.|    .|.|                           ..:.|:...:.::|.|
Mouse   640 LELMGVSSPNPWADATMPEPHTTGQIAGGSLTYCPQYRSEWASQQRGQDSAPSPSGMACVLLGTP 704

  Fly   394 ------------------------------ENSSGL------------------FCDL------- 403
                                          |.:.|:                  ||||
Mouse   705 TLDEPWPGVRNDREELQTCLIKEQLSKSSCEGNLGISRVELVPEEHPPFTAPVSFCDLGGRDLHA 769

  Fly   404 -----------------------------------------------RQPDDCT----------- 410
                                                           |.|..|:
Mouse   770 SRSGSSSACYALATDLPGVLEAVEAQEADVNSYSWNLKELFLKDQTDRTPSHCSCTTSELSEAPS 834

  Fly   411 ----------------IDDIL----------TPVNASNSFPADEFEVG-SQSQVNESSLDKAKSA 448
                            ..|||          |..:.|......|...| .:::::..||..::..
Mouse   835 LSVVGSDLDVGILHRQTSDILVDREMLLLTGTYFDLSEGQRFQEMGAGHDRAELSNISLVSSEHY 899

  Fly   449 STETCDASGSNP-------------------------------ATRLLSSI-NGSFVGEAIHADG 481
            .|...::.|.:|                               ||.|...| .|.:.|...|.||
Mouse   900 ETSDIESPGCDPPLPDPGPNDMCLSAEKPRPSAQITSTPVARGATSLQQEIQEGIYSGSCYHRDG 964

  Fly   482 SVIEVVYSVLLQILPCSNRVYCIWVC-------RNPSTRLDGEKYNYANLTSTFNSMASTVEQSL 539
            ..:.:.:.|....|..|..::|.|:.       |:.:||   .:...|:|.|:.:||......|.
Mouse   965 LQLSIQFEVKRVELQGSATLFCCWLVKDLFHSHRDSATR---TRLFLASLPSSTHSMPELSGSSF 1026

  Fly   540 GQVIKTTA-AQNSSRPNSLSLVSKYEDELYLGDYSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVI 603
            |:|::... .:.|..|..|..::..|     |:|...|.:|..:|.||:|:|..|........|:
Mouse  1027 GEVLRAKPWFEESPTPAELEGLAACE-----GEYDYKYNTISPLGSGAFGFVWTAVEKECNKEVV 1086

  Fly   604 TKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTLNHKNIVSVLDVFENDLFYQLVMEKHGSGMDLW 668
            .|||.|||:.....::......|.:||.:|..::|.||:.|||:|||..|:|||||||||||||:
Mouse  1087 VKFIKKEKVLEDCWIEDPKLGRVTLEIAILSKVDHANIIKVLDIFENQEFFQLVMEKHGSGMDLF 1151

  Fly   669 TFIERRPLMDEKLGSYIFRQVADAVNYLHEQKILHRDIKDENIIIDQNFTIKLIDFGSATFMEEG 733
            .||:..|.:||.|.|:||||:..||.|||.|.|:|||||||||:|.::|||||||||||.::|.|
Mouse  1152 AFIDHHPCLDEPLASFIFRQLVSAVGYLHSQGIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERG 1216

  Fly   734 KFFSTFYGTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLMFFENPFIDVEETLKAEIQIPKAVS 798
            |.|.||.||.|||:||||.||.|.|||||:|:||||||.|:|.||||.:||||::|.|..|..||
Mouse  1217 KLFYTFCGTIEYCAPEVLIGNPYRGPELEMWSLGVTLYTLIFEENPFCEVEETMEAVIHPPFLVS 1281

  Fly   799 EQLSRLLSSMLNKDPKYRCTMHQLITDPWLTQEVNPSTFSFSWIVPCKAHEANPNLYFSGYLYSS 863
            ::|..|||.:|...|:.|.|:.:||.|||:||.||.:  |::|...|:.::..     ||.|.::
Mouse  1282 QELMSLLSGLLQPCPEQRTTLEKLIRDPWVTQPVNLA--SYTWEEVCRTNQPE-----SGLLSAA 1339

  Fly   864 TSVLSTISPQE 874
            :..:.:.||.|
Mouse  1340 SLEIGSRSPSE 1350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914	36/102 (35%)
		PAS	182..350	CDD:441804	63/351 (18%)
		PAS	286..>325	CDD:238075	13/38 (34%)
		STKc_PASK	575..828	CDD:270906	138/252 (55%)
Pask	NP_543126.2	PAS	131..230	CDD:238075	33/98 (34%)
		PAS	342..388	CDD:214512	14/45 (31%)
		STKc_PASK	1058..1311	CDD:270906
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1344..1383