DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pask and Pim3

DIOPT Version :9

Sequence 1:	NP_611864.1	Gene:	Pask / 37824	FlyBaseID:	FBgn0034950	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_663453.1	Gene:	Pim3 / 223775	MGIID:	1355297	Length:	326	Species:	Mus musculus

Alignment Length:	262	Identity:	85/262 - (32%)
Similarity:	138/262 - (52%)	Gaps:	9/262 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   572 YSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTL 636
            :.|.|.....:|.|.:|.|....|.:|.|.|..|.::||::...   .|.....||:|:.||:.:
Mouse    36 FEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEW---GSLGGVAVPLEVVLLRKV 97

  Fly   637 ----NHKNIVSVLDVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQVADAVNYLH 697
                ..:.::.:||.||....:.||:|:.....||:.||..|..:||.|....|.||..||.:.|
Mouse    98 GAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCH 162

  Fly   698 EQKILHRDIKDENIIID-QNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGNRYVGPEL 761
            ...::||||||||:::| ::..:|||||||...::: ..::.|.||..|..||.:..:||.|...
Mouse   163 NCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSA 226

  Fly   762 EIWALGVTLYVLMFFENPFIDVEETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRCTMHQLITDP 826
            .:|:|||.||.::..:.||...||.|:..:...:.||.:..:|:...|:..|..|.::.|:...|
Mouse   227 TVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHP 291

  Fly   827 WL 828
            |:
Mouse   292 WM 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS_9	74..169	CDD:290162
		PAS	74..169	CDD:238075
		PAS_9	286..>335	CDD:290162
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	83/257 (32%)
		S_TKc	576..828	CDD:214567	83/256 (32%)
Pim3	NP_663453.1	PKc_like	39..293	CDD:354810	83/257 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2244
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940