DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Pask and PIM2

Sequence 1:NP_611864.1 Gene:Pask FlyBaseID:FBgn0034950 Length:985 Species:Drosophila melanogaster
Sequence 2:NP_006866.2 Gene:PIM2 HGNCID:8987 Length:311 Species:Homo sapiens

Alignment Length:283 Identity:87/284 (31%)
Similarity:143/284 (50%) Gaps:22/284 (8%)


  Fly   563 YEDELYLGDYSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVP 627
            :|.|..||..         :|:|.:|.|....|.:|||.|..|.|.:.::.....:.  |....|
Human    28 FEAEYRLGPL---------LGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLS--DSVTCP 81

  Fly   628 IEIHLLQTL----NHKNIVSVLDVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQ 688
            :|:.||..:    .|..::.:||.||....:.||:|:.....||:.:|..:..:.|......|.|
Human    82 LEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQ 146

  Fly   689 VADAVNYLHEQKILHRDIKDENIIID-QNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLA 752
            |..|:.:.|.:.::|||||||||:|| :....|||||||...:.: :.::.|.||..|..||.::
Human   147 VVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHD-EPYTDFDGTRVYSPPEWIS 210

  Fly   753 GNRYVGPELEIWALGVTLYVLMFFENPFIDVEETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRC 817
            .::|......:|:||:.||.::..:.||...:|.|:||:..|..||.....|:...|...|..|.
Human   211 RHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP 275

  Fly   818 TMHQLITDPWL---TQEV--NPS 835
            ::.:::.|||:   .::|  |||
Human   276 SLEEILLDPWMQTPAEDVPLNPS 298

Known Domains:


GeneSequenceDomainRegion External IDIdentity
PaskNP_611864.1 PAS_9 74..169 CDD:290162
PAS 74..169 CDD:238075
PAS_9 286..>335 CDD:290162
PAS 286..>325 CDD:238075
STKc_PASK 575..828 CDD:270906 79/258 (31%)
S_TKc 576..828 CDD:214567 79/257 (31%)
PIM2NP_006866.2 STKc_PIM2 31..287 CDD:271003 82/268 (31%)
S_TKc 32..286 CDD:214567 81/266 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R2244
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

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