Protein Alignment Pask and PIM2

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_006866.2
• Gene: PIM2 / 11040
• HGNCID: 8987
• Length: 311
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 87/283 - (30%)
• Similarity: 143/283 - (50%)
• Gaps: 22/283 - (7%)

  Fly   563 YEDELYLGDYSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVP 627
            :|.|..||..         :|:|.:|.|....|.:|||.|..|.|.:.::.....:.  |....|
Human    28 FEAEYRLGPL---------LGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLS--DSVTCP 81

  Fly   628 IEIHLLQTL----NHKNIVSVLDVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQ 688
            :|:.||..:    .|..::.:||.||....:.||:|:.....||:.:|..:..:.|......|.|
Human    82 LEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQ 146

  Fly   689 VADAVNYLHEQKILHRDIKDENIIID-QNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLA 752
            |..|:.:.|.:.::|||||||||:|| :....|||||||...:.: :.::.|.||..|..||.::
Human   147 VVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHD-EPYTDFDGTRVYSPPEWIS 210

  Fly   753 GNRYVGPELEIWALGVTLYVLMFFENPFIDVEETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRC 817
            .::|......:|:||:.||.::..:.||...:|.|:||:..|..||.....|:...|...|..|.
Human   211 RHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP 275

  Fly   818 TMHQLITDPWL---TQEV--NPS 835
            ::.:::.|||:   .::|  |||
Human   276 SLEEILLDPWMQTPAEDVPLNPS 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914
		PAS	182..350	CDD:441804
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	78/257 (30%)
PIM2	NP_006866.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		STKc_PIM2	31..287	CDD:271003	82/267 (31%)