Protein Alignment Galphas and GNAT3

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_001095856.1
• Gene: GNAT3 / 346562
• HGNCID: 22800
• Length: 354
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 154/370 - (41%)
• Similarity: 218/370 - (58%)
• Gaps: 31/370 - (8%)

  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            |.:||...:||..:.::||:|.:....|.:||||||||||||||||||:|:|.:|:|:.|..:..
Human     6 SSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQECMEFK 70

  Fly    81 DDIKKNIRDAILTITGAMSTL-----NPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEE 140
            ..|..|...:||.|..||:||     ||..|.::::.......::|...:      |:..|..:.
Human    71 AVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANTLEDGGMT------PQLAEVIKR 129

  Fly   141 LWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKV 205
            ||:|.|:...:||::||||.|.|.|:|:.:..|....|.|||||:|..||.|:||.||:|....:
Human   130 LWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRVKTTGIIETQFSFKDL 194

  Fly   206 NFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWL 270
            :|.||||||||.||:|||.||..||.|||..|.|:|:|||.||...||:.|||.||.||.|:::.
Human   195 HFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYF 259

  Fly   271 RTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDE 335
            .|.||:|||||:|:..||:.  |..||..|.|:....|..|.|:                :|:::
Human   260 STTSIVLFLNKKDIFQEKVT--KVHLSICFPEYTGPNTFEDAGN----------------YIKNQ 306

  Fly   336 FLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLR 380
            ||.::....|.:  .|.|.|||.||:|:|.||:...|||.:.:|:
Human   307 FLDLNLKKEDKE--IYSHMTCATDTQNVKFVFDAVTDIIIKENLK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	144/339 (42%)
GNAT3	NP_001095856.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		7/20 (35%)
		G-alpha	34..348	CDD:206639	144/339 (42%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	173..181		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	196..205		7/8 (88%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	265..272		5/6 (83%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		3/4 (75%)