Protein Alignment Galphas and Gnai1

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_037277.1
• Gene: Gnai1 / 25686
• RGDID: 2713
• Length: 354
• Species: Rattus norvegicus
• Alignment Length: 383
• Identity: 159/383 - (41%)
• Similarity: 214/383 - (55%)
• Gaps: 37/383 - (9%)

  Fly     1 MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRI 65
            |||         .:::|| |:...||..|.|.|::|.:......:||||||||||||||||||:|
  Rat     1 MGC---------TLSAED-KAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKI 55

  Fly    66 LHVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNY 130
            :|..|:|:.|.||....:..|...:|:.|..||..|........:.::.|..::...|:...| .
  Rat    56 IHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDAARADDARQLFVLAGAAEEGF-M 119

  Fly   131 PPEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGI 195
            ..|.....:.||||.||...:.||.||||.|.|.|:|:.:..|..|||.|.:||:||.||.|:||
  Rat   120 TAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGI 184

  Fly   196 FETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDL 260
            .||.|....::|.||||||||.||:|||.||..||||||..|.|.|::||.||...||:.||:.|
  Rat   185 VETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKL 249

  Fly   261 FKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEF---NKYQTPIDTGDAIMESNDD 322
            |.||.||:|....||||||||:||..||||  ||.|:..:.|:   |.|:
  Rat   250 FDSICNNKWFTDTSIILFLNKKDLFEEKIK--KSPLTICYPEYAGSNTYE--------------- 297

  Fly   323 PEVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLR 380
                .|..:|:.:|..::... |.|. .|.|||||.||:|::.||:...|:|.:.:|:
  Rat   298 ----EAAAYIQCQFEDLNKRK-DTKE-IYTHFTCATDTKNVQFVFDAVTDVIIKNNLK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	146/337 (43%)
Gnai1	NP_037277.1	G-alpha	34..348	CDD:206639	146/337 (43%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	173..181		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	196..205		7/8 (88%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	265..272		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		3/4 (75%)