Protein Alignment Galphas and gpa-8

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_506160.1
• Gene: gpa-8 / 179731
• WormBaseID: WBGene00001670
• Length: 364
• Species: Caenorhabditis elegans
• Alignment Length: 380
• Identity: 128/380 - (33%)
• Similarity: 203/380 - (53%)
• Gaps: 33/380 - (8%)

  Fly     1 MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRI 65
            ||...|  |:...::.|:.|.|...:.:|...|:||:::  ...:||:||.|||||||.:||::|
 Worm     1 MGALCS--SETYMLDKEEYKKQVEHNKSIENDLEKDRKI--KILKLLILGPGESGKSTTIKQIKI 61

  Fly    66 LHVDGFSDSEKKQKIDDIKKNIRDAI----LTITGAMSTLNPPVALEKKENEPRVEYIQDYASSP 126
            :|.:|:|..||..:...|..||.:.|    |::.....:...|::.: ..||.|: :.:::..:.
 Worm    62 IHDEGYSAEEKMVRKHGIYMNILEGIEEIHLSVGRENKSYKNPLSFD-HINEVRM-FTENFKKAD 124

  Fly   127 DFN--YPPEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCR 189
            |..  ..||.....::..||:.:.........|.:.|...|||:..|.|...:|.|.|:|||:.|
 Worm   125 DSEKLLGPEVINAIQKYIKDETIAMMLRDKTVYNIDDSTIYFLENFSRIIQKDYLPTEEDILKSR 189

  Fly   190 VLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRL 254
            |.|||:.:.:..:...||.:|||||||.:||||:..|:||.|::|:|:.|.|:.|||||.|.||:
 Worm   190 VPTSGVIQYKIMLKNFNFRIFDVGGQRAQRRKWLHVFDDVQAVLFITSLSEYDQVLREDATVNRM 254

  Fly   255 RESLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMES 319
            :|||:||:.|.|.|:....::||||||.||...|||.....::     ...|:.|.:...|:
 Worm   255 KESLNLFEKICNGRYFLNTAMILFLNKIDLFKIKIKHTNITVA-----LTSYKGPQECDSAL--- 311

  Fly   320 NDDPEVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDII 374
                      .:||..|:.::.   :.|...|.|.|||.|||.|:.|.:...|::
 Worm   312 ----------DYIRKRFISLNK---NKKRSIYEHVTCATDTEQIQVVIDSVIDVV 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	117/337 (35%)
gpa-8	NP_506160.1	G_alpha	22..343	CDD:214595	118/345 (34%)