Protein Alignment Galphas and goa-1

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_492108.1
• Gene: goa-1 / 172505
• WormBaseID: WBGene00001648
• Length: 354
• Species: Caenorhabditis elegans
• Alignment Length: 382
• Identity: 161/382 - (42%)
• Similarity: 208/382 - (54%)
• Gaps: 35/382 - (9%)

  Fly     1 MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRI 65
            |||          ..|::.::...||..|.:.|::|........:||||||||||||||||||:|
 Worm     1 MGC----------TMSQEERAALERSRMIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKI 55

  Fly    66 LHVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNY 130
            :|..||:..:.||....:..|...:::.|..|||.|.  |:....:.|...:.:.|..:..:...
 Worm    56 IHESGFTAEDYKQYKPVVYSNTVQSLVAILRAMSNLG--VSFGSADREVDAKLVMDVVARMEDTE 118

  Fly   131 P--PEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTS 193
            |  .|.....:.||.|.||...:.|||||||.|.||||||.:..:....|.|.||||||.||.|:
 Worm   119 PFSEELLSSMKRLWGDAGVQDCFSRSNEYQLNDSAKYFLDDLERLGEAIYQPTEQDILRTRVKTT 183

  Fly   194 GIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESL 258
            ||.|..|....:||.:|||||||.||:|||.||.|||||||..|.|.|:.||.||.|.||:.|||
 Worm   184 GIVEVHFTFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMHESL 248

  Fly   259 DLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDP 323
            .||.||.||:|....||||||||:||..||||  ||.|:..|.|::..|
 Worm   249 KLFDSICNNKWFTDTSIILFLNKKDLFEEKIK--KSPLTICFPEYSGRQ---------------- 295

  Fly   324 EVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLR 380
            :...|..:|:.:| .....|.:.:.||  |.|||.||.||:.||:...|:|...:||
 Worm   296 DYHEASAYIQAQF-EAKNKSANKEIYC--HMTCATDTTNIQFVFDAVTDVIIANNLR 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	150/336 (45%)
goa-1	NP_492108.1	G-alpha	34..348	CDD:206639	150/336 (45%)