Protein Alignment Galphas and Gnaq

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_032165.3
• Gene: Gnaq / 14682
• MGIID: 95776
• Length: 359
• Species: Mus musculus
• Alignment Length: 372
• Identity: 152/372 - (40%)
• Similarity: 215/372 - (57%)
• Gaps: 26/372 - (6%)

  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            ||::|..:|.:|.|.|||::||:..|...:|||||.|||||||.:|||||:|..|:||.:|:...
Mouse    12 SEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFT 76

  Fly    81 DDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDK 145
            ..:.:||..|:..:..||.||..|...|..:...::....|......|..|  :.:..:.||.|.
Mouse    77 KLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENP--YVDAIKSLWNDP 139

  Fly   146 GVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMF 210
            |:.:.|:|..||||.|..||:|:.:..:.:|:|.|.:||:||.||.|:||.|..|.:..|.|.|.
Mouse   140 GIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMV 204

  Fly   211 DVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISI 275
            ||||||.||||||.||.:||:|:|:.|.|.|:.||.|...:||:.||..||::|....|.:..|:
Mouse   205 DVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSV 269

  Fly   276 ILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDP--EVIRAKYFIRDEFLR 338
            ||||||:|||.|||.  .|.|.:||.|:                 |.|  :...|:.||...|:.
Mouse   270 ILFLNKKDLLEEKIM--YSHLVDYFPEY-----------------DGPQRDAQAAREFILKMFVD 315

  Fly   339 ISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
            ::.   |.....|.|||||.|||||:.||...:|.|.:::|::|.|:
Mouse   316 LNP---DSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	137/336 (41%)
Gnaq	NP_032165.3	G-alpha	40..353	CDD:206639	137/336 (41%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	41..54		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	178..186		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	201..210		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	270..277		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	329..334		3/4 (75%)