Protein Alignment Galphas and Gnal

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_796111.2
• Gene: Gnal / 14680
• MGIID: 95774
• Length: 448
• Species: Mus musculus
• Alignment Length: 379
• Identity: 261/379 - (68%)
• Similarity: 312/379 - (82%)
• Gaps: 6/379 - (1%)

  Fly    10 KQSDVNSED---SKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGF 71
            :|..:.:|:   :|..::.|..|.|.|::.|:..:.||||||||||||||||||||||||||:||
Mouse    73 RQEQLRAEEREAAKEARKVSRGIDRMLREQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGF 137

  Fly    72 SDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYE 136
            :..||||||.||:||::|||:||..||||:.|||.|...||:.|.:||:..|...||.|..||::
Mouse   138 NPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFD 202

  Fly   137 HTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQ 201
            |.::||.|:||...:||||||||||||:|||:|:.::...:|||.:||:||||||||||||||||
Mouse   203 HVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQ 267

  Fly   202 VDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWN 266
            ||||||||||||||||||||||||||||||||:|.||||||||:|||...||||||||||:||||
Mouse   268 VDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWN 332

  Fly   267 NRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYF 331
            |||||||||||||||||:||||:.|||||:.:||.|:..|..|   .||..::.:||:|.|||:|
Mouse   333 NRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP---EDATPDAGEDPKVTRAKFF 394

  Fly   332 IRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
            |||.|||||||:||||||||||||||||||||:|||||||||||||||:|||||
Mouse   395 IRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	245/334 (73%)
Gnal	NP_796111.2	G-alpha	110..442	CDD:206639	245/334 (73%)