Protein Alignment Galphas and Gnai3

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_034436.1
• Gene: Gnai3 / 14679
• MGIID: 95773
• Length: 354
• Species: Mus musculus
• Alignment Length: 381
• Identity: 157/381 - (41%)
• Similarity: 215/381 - (56%)
• Gaps: 31/381 - (8%)

  Fly     1 MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRI 65
            |||         .:::|| |:...||..|.|.|::|.:......:||||||||||||||||||:|
Mouse     1 MGC---------TLSAED-KAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKI 55

  Fly    66 LHVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNY 130
            :|.||:|:.|.||....:..|...:|:.|..||..|........:.::.|..::. ..|:.:...
Mouse    56 IHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGESARADDARQLFVL-AGSAEEGVM 119

  Fly   131 PPEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGI 195
            ..|.....:.||:|.||...:.||.||||.|.|.|:|:.:..|...||.|.:||:||.||.|:||
Mouse   120 TSELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRVKTTGI 184

  Fly   196 FETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDL 260
            .||.|...::.|.||||||||.||:|||.||..||||||..|.|.|::||.||...||:.||:.|
Mouse   185 VETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKL 249

  Fly   261 FKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEV 325
            |.||.||:|....||||||||:||..||||  :|.|:..:.|:        ||....|
Mouse   250 FDSICNNKWFTDTSIILFLNKKDLFEEKIK--RSPLTICYPEY--------TGSNTYE------- 297

  Fly   326 IRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQ 381
             .|..:|:.:|..::... |.|. .|.|||||.||:|::.||:...|:|.:.:|::
Mouse   298 -EAAAYIQCQFEDLNRRK-DTKE-VYTHFTCATDTKNVQFVFDAVTDVIIKNNLKE 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	144/334 (43%)
Gnai3	NP_034436.1	G-alpha	34..348	CDD:206639	144/334 (43%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	173..181		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	196..205		7/8 (88%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	265..272		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		3/4 (75%)