Protein Alignment Galphas and Galphao

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: XP_061496688.1
• Gene: Galphao / 1276442
• VectorBaseID: AGAMI1_003451
• Length: 354
• Species: Anopheles gambiae
• Alignment Length: 384
• Identity: 164/384 - (42%)
• Similarity: 213/384 - (55%)
• Gaps: 39/384 - (10%)

  Fly     1 MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRI 65
            |||          ..|.:.::...||..|.|.|::|........:||||||||||||||||||:|
Mosquito     1 MGC----------AQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKI 55

  Fly    66 LHVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNY 130
            :|..||:..:.||....:..|...:::.|..||..|:  :|....|.|...:.:.|.........
Mosquito    56 IHESGFTSEDFKQYRPVVYSNTIQSLVAILRAMPNLS--IAFGNNERECDAKMVFDVVQRMHDTE 118

  Fly   131 PPEFYEH----TEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVL 191
            |  |.|.    .:.||.|.||.:.:.|||||||.|.||||||.:..:...:|.|.||||||.||.
Mosquito   119 P--FSEDLLLAMKRLWSDSGVQECFCRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVK 181

  Fly   192 TSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRE 256
            |:||.|..|....:||.:|||||||.||:|||.||.|||||||..|.|.|:.||.||.|.||::|
Mosquito   182 TTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQE 246

  Fly   257 SLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESND 321
            ||.||.||.||:|....||||||||:||..|||:  ||.|:..|.|:        ||.  .|..:
Mosquito   247 SLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIR--KSPLTICFPEY--------TGG--QEYGE 299

  Fly   322 DPEVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLR 380
            ....|:|::..:::    ||:.   :.||  |.|||.||.||:.||:...|:|...:||
Mosquito   300 AAAYIQAQFEAKNK----STSK---EIYC--HMTCATDTNNIQFVFDAVTDVIIANNLR 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	152/338 (45%)
Galphao	XP_061496688.1	None