Protein Alignment: DNAlig1 and lig3

• Sequence 1: NP_611843.2
• Gene: DNAlig1
• FlyBaseID: FBgn0262619
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_001025345.2
• Gene: lig3
• ZFINID: ZDB-GENE-030131-8453
• Length: 1011
• Species: Danio rerio
• Alignment Length: 802
• Identity: 200/803 (25%)
• Similarity: 332/803 (41%)
• Gaps: 154/803 (19%)

  Fly     5 ITSFFKKKSDATDSPSPPKKVPKIDAKTELPDE------PHIKSESASPETKPKVE---PMSVDS 60
            :...|:|...|..:....:.:.:::...||.||      .|:...:|...:.||.:   .::...
Zfish   139 VKCIFEKLERARATTKKIEDITELEGWEELQDEDKDLINKHVSELAAKVNSTPKKKVQAKLNTSG 203

  Fly    61 EEKTSPVKNVKKEPKEVDDKTTDKKVTTIGLNSTAATKEDVENYDPSADSYHPLKNAYWKDKKVT 125
            :..:.|.......|::....|              |||....:..|......|.:.:....:...
Zfish   204 QLSSPPADPTVNAPRKFSGFT--------------ATKAGSSSSSPGPSPAKPAQGSVLSAQMCD 254

  Fly   126 PYLA--LARTFQ----VIEETKGRLKMIDTLSNFFCSVMLVSPEDLVPSVYLSINQLAPAYEGLE 184
            |...  |.|.|:    ::.|..|.....:.:.:|.....  ..:.....:||::..|.|
Zfish   255 PTHKDNLLREFRKLCALVAEKSGYNAKTEIVRDFLTKGS--GGDKFRGDLYLTVKLLLP------ 311

  Fly   185 LGVAETTLM---KAICKATGRNLAHIKSQTQLTGDLGIVAEQSRVSQ--RMMFQPAP-------- 236
             ||.:....   |.|.|...|.|.  .:|..:..||    ||..||:  ||.|:.:.
Zfish   312 -GVVKNVYNLNDKQIVKLFSRILN--CNQDDMVQDL----EQGDVSETVRMFFEESKSFPPSAKS 369

  Fly   237 -LNVRDVFRKLREIAKLSGQSKMDL-VYNMFVACRSSEARFFIRSLIGKLRIGIAEQSLLTALAI 299
             |.:::|...|..:::|:.:..... :.::...|..::.:.:||.:...|:|....:.:|.|
Zfish   370 LLTIQEVDASLSRLSQLTKEDDQQAELQSIAKKCTGNDLKCYIRLVKHDLKINSGAKHILDA--- 431

  Fly   300 GLVKKNHIDDCKASKVPDVYKDEIVDTTLLLK--TAYCQCPNYDIIIPAILKYDIKELQERCPMH 362
              |..|..|..|||:    ...:::|..|..:  .:....|...:.|.|.|.
Zfish   432 --VDPNAYDAFKASR----NLGDVIDRVLRNQQDASNGTGPRKILSIEASLM------------- 477

  Fly   363 PGMPLRPMLAQPTKGVHEVFERF-GGMQITCEWKYDGERAQIHRNEKGEISIFSRNSE----NNT 422
              .|::||||:..|.:....::. .||.  .|.||||||.|:|:| ....|.|||:.:    :..
Zfish   478 --TPVQPMLAEACKSIEYAMKKCPNGMY--SEIKYDGERVQVHKN-GNHFSYFSRSLKPVLPHKV 537

  Fly   423 AKYPDLIARSTALLKGDVKSYIIDSEIVAWDVERKQILPFQVLSTRKRKNVDIEEIKVQVCVYIF 487
            |.:.|.|.::.|    ...|.|:|:|::..|.:..:.|||..|...|:....    ..||.:::|
Zfish   538 AHFKDFIPQAFA----GGHSMILDAEVLLIDTKTSKPLPFGTLGVHKKAAFQ----DAQVGLFVF 594

  Fly   488 DLLYINGTALVTKNLSERRKLLLEHFQEVEGEWKFATALDTNDIDEVQQFLEESIKGNCEGLMVK 552
            |.:|.||.:|:.|.|.||||.|.::..||.....|:.........::.:.:...|:...|||::|
Zfish   595 DCIYFNGVSLMDKPLCERRKFLHDNMVEVPNRILFSEMKHVTRAPDLAEMITRVIREGLEGLVLK 659

  Fly   553 TLDEEATYEIAKRSRNWLKLKKDYLSN--VGDSLDLVVIGGYKGKGRRTGTYGGFLLACYDTENE 615
              |.:..||..|  |:|||:|||||:.  :.|:.||||:|.:.|||...|....||:.|||.|:.
Zfish   660 --DIKGLYEPGK--RHWLKVKKDYLNEGAMADTADLVVLGAFYGKGSNGGIMSSFLMGCYDPESR 720

  Fly   616 EYQSICKIGTGFTD-------EDLQTHSEFLGKHVT------SAAKSYYR----YDPSLEPDHWF 663
            ::.::.|...||.|       :||....  :||..:      ...|:||.    .||...|
Zfish   721 KWCTVTKCSGGFDDAMLDRLQKDLDVIK--IGKDPSKIPGWLKIVKNYYPDFIIRDPQKAP---- 779

  Fly   664 EPVQVWEVKCADLSLSPIHRAAIGIVDGERGISLRFPRFIRIRDDKNSENATDANQVAHMYQ--- 725
                |||:..|:.|.|.:|.|        .|||:||||..|:||||:.:.||:..|:..:|:
Zfish   780 ----VWEITGAEFSKSEMHTA--------DGISIRFPRCTRMRDDKDWKTATNLQQLKELYRISK 832

  Fly   726 ---------SQDQVKNNQKSST 738
                     ...:...|.|||:
Zfish   833 ENCDFEVTAGPSKANQNDKSSS 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig1	NP_611843.2	PLN03113	1..745	CDD:215584	200/803 (25%)
		DNA_ligase_A_N	126..292	CDD:282522	37/187 (20%)
		Adenylation_DNA_ligase_I_Euk	358..576	CDD:185710	70/223 (31%)
		OBF_DNA_ligase_I	581..726	CDD:153438	54/174 (31%)
lig3	NP_001025345.2	zf-PARP	95..178	CDD:279039	7/39 (18%)
		DNA_ligase_A_N	263..428	CDD:282522	35/180 (19%)
		dnl1	317..829	CDD:273147	164/575 (29%)
		Adenylation_DNA_ligase_III	467..679	CDD:185712	73/242 (30%)
		OBF_DNA_ligase_III	685..823	CDD:153436	52/156 (33%)
		LIG3_BRCT	935..1006	CDD:293364

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG1793
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D274264at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910