DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment: PHDP and ALX1

Sequence 1:NP_523834.1 Gene:PHDP FlyBaseID:FBgn0025334 Length:220 Species:Drosophila melanogaster
Sequence 2:NP_008913.2 Gene:ALX1 HGNCID:1494 Length:326 Species:Homo sapiens

Alignment Length:177 Identity:72/178 (40%)
Similarity:89/178 (50%) Gaps:26/178 (15%)


  Fly    20 NSEFYNSGANG------GGLSVANHINHYNLMIDSSYKLCANESAIRGSLNQESSLLFSKITTVS 78
            |..||:..:.|      |.|..|.|  |..|...|.   |.:.|...|....|...|.:::..  
Human    37 NESFYSKASAGKCVQAFGPLPRAEH--HVRLERTSP---CQDSSVNYGITKVEGQPLHTELNR-- 94

  Fly    79 EFYPATHNIGSYNTD--------FHLKSYGDDGLSLTDKSKQRRIRTTFTSNQLNELEKIFLETH 135
                |..|..|....        ..|...||...|....||:||.||||||.||.||||:|.:||
Human    95 ----AMDNCNSLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTH 155

  Fly   136 YPDIYTREEIASKLHLTEARVQVWFQNRRAKFRKQERHAIYIMKDKS 182
            |||:|.||::|.:..||||||||||||||||:||:||:. .|.:.||
Human   156 YPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYG-QIQQAKS 201

Known Domains:


GeneSequenceDomainRegion External IDIdentity
PHDPNP_523834.1 Homeobox 116..168 CDD:278475 38/52 (73%)
ALX1NP_008913.2 Homeobox 135..188 CDD:306543 38/53 (72%)
Transactivation domain. {ECO:0000250|UniProtKB:Q63087} 192..326 4/12 (33%)
OAR 302..320 CDD:309087
OAR. {ECO:0000255|PROSITE-ProRule:PRU00138} 306..319
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 O PTHR24329
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.