Protein Alignment PHDP and Isx

DIOPT Version :10

• Sequence 1: NP_523834.1
• Gene: PHDP / 37788
• FlyBaseID: FBgn0025334
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_001281207.1
• Gene: Isx / 71597
• MGIID: 1918847
• Length: 242
• Species: Mus musculus
• Alignment Length: 369
• Identity: 73/369 - (19%)
• Similarity: 117/369 - (31%)
• Gaps: 133/369 - (36%)

  Fly   152 LTILLVWAISAAIGSPIVLGLNNTQDRSPDLCVFYNTDFIVYSSLTSFYIPCIIMVF----LYW- 211
            |.:||..:::...|||::|..|....|..|:.|..:...:|.|.|..  ...:..:|    ::|
Mouse    15 LELLLCCSLTVIRGSPLLLFANRRDVRLVDVEVGRSESAVVVSDLED--AAAVDFLFSEGLIFWT 77

  Fly   212 --------NIFKALRTRAKKQRAARKPHLSEITA------------GGSIIENIAQTKRLAETQL 256
                    ..:..|.|.:.|:....|.....::.            |..:....::|.|:....|
Mouse    78 DVSEEAIKQTYYNLSTNSMKEATLGKGQTVVVSGLDSPDGLACDWLGHKLYWTDSETNRIEVANL 142

  Fly   257 DGSTRSGSKIL--PDEERPTNTA------------------------SGSNEEDD-------ENA 288
            ||::|   |:|  .|.::|...|                        .|||.:..       .|.
Mouse   143 DGTSR---KVLFWQDLDQPRAIALNPSHRYMYWTDWGEEPRIERAGMDGSNRQIIVQKQIYWPNG 204

  Fly   289 GSPDIDDCHVIVNDKSTEFM---------LATVVEEAGNVTLKPLSLVRCGVQQALTLNRNDSTL 344
            .:.|:|:..:...|....|:         ...|||  |::| .|.         ||||  .|.||
Mouse   205 LTIDLDEQKLYWADAKLSFIHRANLDGTSREAVVE--GSLT-HPF---------ALTL--YDETL 255

  Fly   345 STNSRDSSRKDKKNTQASRFTIYKVNKASKKKREK----------------------SSAKKERK 387
            ..            |.....:|:..||.|.:|..:                      .:...||.
Mouse   256 YW------------TDWQTRSIHACNKHSGEKHREILNGIYSPMDIQVLGQERQPNIQTPCSERN 308

  Fly   388 ATKTLAIVLGVFLFCWV----PFFTCNIMDAMCAKLD-KDCRPG 426
            .        |....|.:    ||::|.....:..|.| |.||||
Mouse   309 G--------GCSHLCLLSPIPPFYSCACPTGVKLKEDGKTCRPG 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeodomain	113..169	CDD:459649	6/16 (38%)
Isx	NP_001281207.1	Homeodomain	79..135	CDD:459649	5/55 (9%)