DRSC/TRiP Functional Genomics Resources

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Protein Alignment PHDP and ARX

DIOPT Version :10

Sequence 1:NP_523834.1 Gene:PHDP / 37788 FlyBaseID:FBgn0025334 Length:220 Species:Drosophila melanogaster
Sequence 2:NP_620689.1 Gene:ARX / 170302 HGNCID:18060 Length:562 Species:Homo sapiens


Alignment Length:82 Identity:50/82 - (60%)
Similarity:62/82 - (75%) Gaps:9/82 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   100 GDDGLSLTD---------KSKQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIASKLHLTEAR 155
            |:|.:.|:.         |.||||.||||||.||.|||:.|.:|||||::||||:|.:|.|||||
Human   307 GEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEAR 371

  Fly   156 VQVWFQNRRAKFRKQER 172
            |||||||||||:||:|:
Human   372 VQVWFQNRRAKWRKREK 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PHDPNP_523834.1 Homeodomain 113..169 CDD:459649 41/55 (75%)
ARXNP_620689.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 50..81
GCG-encoded polyalanine repeat 102..111
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..255
Homeodomain 329..385 CDD:459649 41/55 (75%)
OAR 526..544 CDD:461067
OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138 530..543
Blue background indicates that the domain is not in the aligned region.

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