Protein Alignment CG18128 and MTAP

DIOPT Version :10

• Sequence 1: NP_611822.1
• Gene: CG18128 / 37756
• FlyBaseID: FBgn0034898
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_001382973.1
• Gene: MTAP / 4507
• HGNCID: 7413
• Length: 346
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 53/240 - (22%)
• Similarity: 96/240 - (40%)
• Gaps: 34/240 - (14%)

  Fly    66 KYGLICGSFLSDMVSLVEQPVVI-----PYEDIPNFPDGIEPDCSFVLGTVMGAPIIALVHSFHS 125
            |.|:|.|:.|.|       |.::     .|.|.| |.   :|..:.:||.:.....:.|..
Human    11 KIGIIGGTGLDD-------PEILEGRTEKYVDTP-FG---KPSDALILGKIKNVDCVLLAR---- 60

  Fly   126 CDGYNLATCALPVRV--------MQLCGVRTIMLTSEAAAVDHGFALGDIMLVQDHINVVGMMHQ 182
               :......:|.:|        ::..|...:::|:...::......|||:::...|:...|..|
Human    61 ---HGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQ 122

  Fly   183 TPLEGPSDPRFGSRRFSMVNAYDKDLLEKALEIGKRMGIQKFLHS-GVLACMGGPILGTVAEERM 246
            :..:|......|.....|...:.....|..:|..|::|::  .|| |.:..:.||...:.||..|
Human   123 SFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLR--CHSKGTMVTIEGPRFSSRAESFM 185

  Fly   247 LRTMEVSAVGMSLVPEVIAAHHGGLKVLAFVVISRAASDKESEES 291
            .||.....:.|:.||||:.|...|:...:..:.:.....||.||:
Human   186 FRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEA 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18128	NP_611822.1	PNP-EcPNPII_like	48..290	CDD:350160	51/237 (22%)
MTAP	NP_001382973.1	MTAP_SsMTAPII_like_MTIP	12..255	CDD:350161	52/239 (22%)