DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg3 and Alg3

DIOPT Version :9

Sequence 1:	NP_523829.2	Gene:	Alg3 / 37754	FlyBaseID:	FBgn0011297	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_038944018.1	Gene:	Alg3 / 287983	RGDID:	1306004	Length:	460	Species:	Rattus norvegicus

Alignment Length:	404	Identity:	171/404 - (42%)
Similarity:	226/404 - (55%)	Gaps:	33/404 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KYLLL-EPAALPIVGLFVLLAELVINVVVIQRVPYTEIDWVAYMQECEGFLNGTTNYSLLRGDTG 99
            :|||| ||....:|...:.|||:.|...||.||.||||||.|||.:.|||:|||.:|:.|:||||
  Rat    32 RYLLLREPRYTLMVASCLCLAEVGITFWVIHRVAYTEIDWKAYMAQVEGFINGTYDYTQLQGDTG 96

  Fly   100 PLVYPAAFVYIYSALYYVTSHGTNVRLAQYIFAGIYLLQLALVLRLYSKSRKVPPYVLVLSAFTS 164
            ||||||.|:||::.|||.|..||::..||.|||.:||:.|.||..:|.::.||||:|.......|
  Rat    97 PLVYPAGFLYIFTGLYYATDRGTDIPTAQNIFAVLYLVTLVLVFLIYHQTSKVPPFVFFFMCCAS 161

  Fly   165 YRIHSIYVLRLFNDPVAVLLLYAALNLFLDRRWTLGSTFFSLAVGVKMNILLFAPALLLFYLANL 229
            ||:|||:||||||||||:.||:.::||||.:||:.|...|||||.||||:|||||.||...|...
  Rat   162 YRVHSIFVLRLFNDPVAMALLFLSVNLFLAQRWSWGCCCFSLAVSVKMNVLLFAPGLLFLLLTQF 226

  Fly   230 GLLRTILQLAVCGVIQLLLGAPFLLTHPVEYLRGSFDLGRIFEHKWTVNYRFLSRDLFENRTFHV 294
            |....:.:||:|..:|::||.||||.:||.||..||||||.|.::||||:|.|...:|.:|.||:
  Rat   227 GFRGALPKLALCAALQVVLGLPFLLENPVGYLSRSFDLGRQFLYQWTVNWRLLPEAIFLHRAFHL 291

  Fly   295 SLLGLHLLLLLAFAKPTWTFFQSYVRLRRIEDQLQPQIAQQNLELNAQKRPKKVEKDKDKDQKKF 359
            :||..||..||.||...|......: |..::|..:.::..|.|..|..:................
  Rat   292 ALLAAHLSFLLLFALCRWHRTGESI-LSLLKDPSKRKVPPQPLTPNHHRLSPSSSPPTSLASASA 355

  Fly   360 TTEQQSFLKAFEKSLQKASGGKATPAPAQAEPERY------------------GIHFDRCTQLAL 406
            .....||:           .|.:|..|....|..:                  ||| ......||
  Rat   356 APSTPSFM-----------SGTSTRCPTSCGPRPHAGSHTCSGCWCWDSSSSPGIH-THPHPSAL 408

  Fly   407 LPFFLCNLVGVACS 420
            || :.|..:...||
  Rat   409 LP-YTCATLSPCCS 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg3	NP_523829.2	ALG3	51..470	CDD:282992	164/388 (42%)
Alg3	XP_038944018.1	ALG3	49..337	CDD:398745	147/287 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353207
Domainoid	1	1.000	374	1.000	Domainoid score	I846
eggNOG	1	0.900	-	-		E1_KOG2762
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4228
Inparanoid	1	1.050	393	1.000	Inparanoid score	I1912
OMA	1	1.010	-	-		QHG53696
OrthoDB	1	1.010	-	-		D443928at33208
OrthoFinder	1	1.000	-	-		FOG0004953
OrthoInspector	1	1.000	-	-		oto97712
orthoMCL	1	0.900	-	-		OOG6_103036
Panther	1	1.100	-	-	LDO	PTHR12646
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3495
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770