DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment angel and CCR4

DIOPT Version :9

Sequence 1:	NP_477204.1	Gene:	angel / 37748	FlyBaseID:	FBgn0016762	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_009381.1	Gene:	CCR4 / 851212	SGDID:	S000000019	Length:	837	Species:	Saccharomyces cerevisiae

Alignment Length:	382	Identity:	99/382 - (25%)
Similarity:	151/382 - (39%)	Gaps:	100/382 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 EMESSHDRNRRWTSLGNQAE--GRDPHKCSSFKVVSYNILAQDLLLEHLFLYVGIPHEFLSWQRR 101
            |:.:..:..|.:.||....|  ..|..| .:|.|:|||.|.|......::.|.  |...|||..|
Yeast   475 EINTDGEPQREYDSLQQSTEHLATDLAK-RTFTVLSYNTLCQHYATPKMYRYT--PSWALSWDYR 536

  Fly   102 QQNLLRELLKLDPDILCLQEMQ---FDH--LPVLVQRLRMG--NGKKLAYVYKKKTGCRTDGCAI 159
            :..|..::|..|.|:|||||::   |:.  :|:|.:....|  :.|..|.....|...:.|||.|
Yeast   537 RNKLKEQILSYDSDLLCLQEVESKTFEEYWVPLLDKHGYTGIFHAKARAKTMHSKDSKKVDGCCI 601

  Fly   160 VYDSSKFELLDHQAVEL-------------YDQAVALLNRDNVALFARFRFKKQQEQQKEFVVA- 210
            .:...:|:|:...|::.             .|.....:|:||||||    .|.|.....:.:.|
Yeast   602 FFKRDQFKLITKDAMDFSGAWMKHKKFQRTEDYLNRAMNKDNVALF----LKLQHIPSGDTIWAV 662

  Fly   211 TTHLLFNTKRSDVRCAQVERILEELQ---------SFSTDT---PIVLTGDFNSLPDSSPIEFLV 263
            ||||.::.|.:||:..||..:|:.|:         :|..|.   |:::.|||||..:|:..|.:
Yeast   663 TTHLHWDPKFNDVKTFQVGVLLDHLETLLKEETSHNFRQDIKKFPVLICGDFNSYINSAVYELI- 726

  Fly   264 GKNGDVDSTACPEPLHFEIIDSGEGTASTYQNE----------------------------WVIV 300
             ..|.|           :|...|.|....|.:|                            ..::
Yeast   727 -NTGRV-----------QIHQEGNGRDFGYMSEKNFSHNLALKSSYNCIGELPFTNFTPSFTDVI 779

  Fly   301 DYI------LRSLGSRSRHKLLPLSVYSLPSINRCIGAGQIPNYRLGSDHYALGAVF 351
            |||      ||..|.        |.......:::.||   .||.:..|||..|.|.|
Yeast   780 DYIWFSTHALRVRGL--------LGEVDPEYVSKFIG---FPNDKFPSDHIPLLARF 825

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
angel	NP_477204.1	EEP	70..351	CDD:294334	90/347 (26%)
CCR4	NP_009381.1	LRR	<213..474	CDD:227223
		leucine-rich repeat	339..358	CDD:275378
		leucine-rich repeat	359..381	CDD:275378
		leucine-rich repeat	382..404	CDD:275378
		leucine-rich repeat	405..427	CDD:275378
		leucine-rich repeat	428..439	CDD:275378
		CCR4	476..837	CDD:227564	98/381 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810