DRSC/TRiP Functional Genomics Resources

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Protein Alignment: angel and Cnot6

Sequence 1:NP_477204.1 Gene:angel FlyBaseID:FBgn0016762 Length:354 Species:Drosophila melanogaster
Sequence 2:NP_001277670.1 Gene:Cnot6 MGIID:2144529 Length:557 Species:Mus musculus

Alignment Length:454 Identity:108/455 (24%)
Similarity:172/455 (38%) Gaps:149/455 (33%)


  Fly     6 LHNVSLKA---TSRII---------RRSVSSQAKGASGKRKQKAKEMESSHDRNRRWTSLGNQAE 58
            |..:|||.   |..|:         ||.::......||    .||.:.:.....|.|..|     
Mouse   122 LQTLSLKGNPLTQDILNLCLEPDGTRRLLNYLLDNLSG----TAKRISTEQPPPRSWIML----- 177

  Fly    59 GRDPHK---CSSFKVVSYNILAQDLLLEHLFLYVGIPHEFLSWQRRQQNLLRELLKLDPDILCLQ 120
             ::|.:   .:.|.|:.||:|........|:.|  .|...|:|..|::.:::|:|..:.||:.||
Mouse   178 -QEPDRTRPTALFSVMCYNVLCDKYATRQLYGY--CPSWALNWDYRKKAIIQEILSCNADIISLQ 239

  Fly   121 EMQFD--HLPVLVQRLRMG-NGKKLAYVYKKKTGCRT---------DGCAIVYDSSKFELLDHQA 173
            |::.:  :...||:....| ||     .:..|:..||         |||||.:.:.||.|:....
Mouse   240 EVETEQYYSFFLVELKERGYNG-----FFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHT 299

  Fly   174 VELYDQAV-------ALLNR----DNVALFARFRFKKQQEQ----------QKEFV-VATTHLLF 216
            ||....|:       |:|||    ||:.:......:|:..:          :|:.: ||..|:.:
Mouse   300 VEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKELIEMSSGKPHLGTEKQLILVANAHMHW 364

  Fly   217 NTKRSDVRCAQVERILEELQSFSTDT---------------PIVLTGDFNSLPDSSPIEFLV--- 263
            :.:.|||:..|....|.|:::.....               |:||..|.||||||..:|:|.   
Mouse   365 DPEYSDVKLVQTMMFLSEVKNIIDKASRSLKSSVLGECGTIPLVLCADLNSLPDSGVVEYLSTGG 429

  Fly   264 -----------------------GKNGDVDSTACPEPLHFEIIDSGEGTASTYQNEWV------- 298
                                   ||||..:..          |..|....|.|:|..:       
Mouse   430 VETNHKDFKELRYNESLTNFSCNGKNGMTNGR----------ITHGFKLKSAYENGLMPYTNYTF 484

  Fly   299 ----IVDYILRS---------LGSRSRHKLLPLSVYSLPSINRCIGAGQIPNYRLGSDHYALGA 349
                |:|||..|         ||....|.|:.      .:|:.|      |:..:.|||::|.|
Mouse   485 DFKGIIDYIFYSKPQLNTLAILGPLDHHWLVE------NNISGC------PHPLIPSDHFSLFA 536

Known Domains:


GeneSequenceDomainRegion External IDIdentity
angelNP_477204.1 EEP 70..351 CDD:294334 91/376 (24%)
Cnot6NP_001277670.1 LRR <52..>159 CDD:227223 9/37 (24%)
LRR 1 52..73
leucine-rich repeat 53..75 CDD:275378
LRR 2 75..96
leucine-rich repeat 76..98 CDD:275378
LRR 3 98..120
leucine-rich repeat 99..121 CDD:275378
LRR 4 121..143 6/21 (29%)
leucine-rich repeat 122..133 CDD:275378 4/11 (36%)
Nuclease domain. {ECO:0000250} 153..557 100/424 (24%)
Deadenylase_CCR4a 191..540 CDD:197340 91/376 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C84185232
eggNOG 1 0.900 E1_COG5239
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.830

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