Protein Alignment l(2)efl and Hspb2

DIOPT Version :10

• Sequence 1: NP_523827.1
• Gene: l(2)efl / 37744
• FlyBaseID: FBgn0011296
• Length: 187
• Species: Drosophila melanogaster
• Sequence 2: NP_569115.1
• Gene: Hspb2 / 161476
• RGDID: 70914
• Length: 182
• Species: Rattus norvegicus
• Alignment Length: 167
• Identity: 57/167 - (34%)
• Similarity: 91/167 - (54%)
• Gaps: 22/167 - (13%)

  Fly    22 SRLLDQHFGQGLKRDDLMSSVWNSRPTVLRSGYLRPWHTNSLQKQESG-STLNIDSEKFEVILDV 85
            |||.:|.||:||..:::::      ||:....|:||....:.:...:| |.|.:...||:..|||
  Rat    22 SRLGEQRFGEGLLPEEILT------PTLYHGYYVRPRAARAGEGGRAGASELRLSEGKFQAFLDV 80

  Fly    86 QQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLPSDVNPDTVTSSLSSDGLLTIK 150
            ..|:|.|:||:..|..:.|..:|.::.|.||:|||:|.|.|.||:||:|..|.::||.||:|.::
  Rat    81 SHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLE 145

  Fly   151 AP--------------MKALP-PPQTERLVQITQTGP 172
            ||              :..|| ||..|...::.:..|
  Rat   146 APRGGRHLDTEVNEVYISLLPAPPDPEEEEEVARVEP 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_523827.1	metazoan_ACD	71..153	CDD:107247	36/95 (38%)
Hspb2	NP_569115.1	Crystallin	<21..55	CDD:425732	13/38 (34%)
		alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.	67..148	CDD:469641	35/80 (44%)