DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)efl and si:dkey-1k23.3

DIOPT Version :9

Sequence 1:	NP_001261156.1	Gene:	l(2)efl / 37744	FlyBaseID:	FBgn0011296	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	XP_002662020.3	Gene:	si:dkey-1k23.3 / 100331249	ZFINID:	ZDB-GENE-160113-121	Length:	365	Species:	Danio rerio

Alignment Length:	206	Identity:	67/206 - (32%)
Similarity:	112/206 - (54%)	Gaps:	40/206 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVVPLMFRDWWDELDFPMRTSRLLDQHFGQG--LKRDDL--MSSVW-----NSRPTVLRSGYLR 56
            :|.:||..|  |..:.|        :||||..  |:..||  |..::     :|.|..:|||:|.
Zfish    13 VSWIPLSCR--WPSVIF--------NQHFGMPPLLEPRDLSWMEDIFRRLGTSSWPGYVRSGFLA 67

  Fly    57 PWHTNSLQ-----------KQESGSTLNIDSE--KFEVILDVQQFSPSEITVKVADKFVIVEGKH 108
            |    .||           ::.||....:.:|  ::::.|||..|:|:||:||:...|:.:.|||
Zfish    68 P----LLQASGPAVFSKPHRELSGGVSEVAAETCRWKISLDVNHFAPAEISVKIQHGFLEIAGKH 128

  Fly   109 EEKQDEHGYVSRQFSRRYQLPSDVNPDTVTSSLSSDGLLTIKAPMKALPPPQTERL-VQI---TQ 169
            ||:||.||:::|.|:|:|.||..:..:.:.:|||:||:||::||..::|.|....: :|:   .|
Zfish   129 EERQDGHGFIARSFTRKYNLPGGIEVENLQTSLSADGILTVEAPFPSIPLPADVIIPIQVESGAQ 193

  Fly   170 TGPSSKEDNAK 180
            |....::|..|
Zfish   194 TIAGKQQDGDK 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_001261156.1	metazoan_ACD	71..153	CDD:107247	34/83 (41%)
si:dkey-1k23.3	XP_002662020.3	alpha-crystallin-Hsps_p23-like	88..172	CDD:320797	33/83 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	1	1.000	-	-		FOG0000383
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101545
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820