Protein Alignment CG33964 and mettl25

DIOPT Version :10

• Sequence 1: NP_001033941.1
• Gene: CG33964 / 3772719
• FlyBaseID: FBgn0053964
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: XP_073802771.1
• Gene: mettl25 / 678519
• ZFINID: ZDB-GENE-041210-90
• Length: 594
• Species: Danio rerio
• Alignment Length: 601
• Identity: 168/601 - (27%)
• Similarity: 264/601 - (43%)
• Gaps: 144/601 - (23%)

  Fly     6 VVQLQRRLDGLLAFLNPHWDFVNCHMVNYLTDQHWDGFLS---ETLKSEIAGKEDVALAIED--- 64
            :|.:::::|.:..||:......|.|.|::.|...|..|:|   |.:...|:..:|...|:|:
Zfish     9 IVAVKKKIDEVKHFLSISLSISNAHTVDFYTRGVWSTFISVSPEDVLCAISSTQDSTGALEEKEN 73

  Fly    65 -LFWKTDESERFPAWREFLGKSKQERLSLHPKL--LTSVEELIE-----------GQGNSTQLSI 115
             .|...:.|::.......|..:|...|   |.|  ...:|||:.           ||.::..|:.
Zfish    74 TTFGFCNASKKLLDISALLRAAKAHCL---PGLGVCMQLEELMHNLRLMCGDTAAGQSSNKVLAP 135

  Fly   116 REFMSAKKCHEVDLTAVLVDQLVKNSGQDCF----IVDAGDGKGYLSSRLALQYGHRVLGIDANA 176
            .|||:.||.|||...:.:|..|.|     |.    ::|.|.|||||.|.|:::|..:|.|||::.
Zfish   136 DEFMNWKKAHEVQSMSEVVASLAK-----CCRVKQVIDVGSGKGYLCSYLSMRYNLQVFGIDSST 195

  Fly   177 ANTENALNRNRKLQR-------------------------------AWNGLTER-AELQVQG--- 206
            .||..|..|||||::                               :.|.:|:: .|.|.:.
Zfish   196 TNTHGAQERNRKLKKFSKAYQQHRFIENNCVQSNDESREHYNESDGSKNCITKQGVEAQTESSAL 260

  Fly   207 ---------------------------------------------ITP-----------KRRSKK 215
                                                         :.|           ||.:.:
Zfish   261 SQQVTRDLLASNNAAECPLDPSDSDSGSSFLSLLALDVIEDVSLRVHPSKLSAEERERRKRENLE 325

  Fly   216 SPARESTKSAPALENYKTTAKFITTELNFGALLAENFTQFRPEDSPNICLTGLHTCGNLAATCLQ 280
            ..|||..:.......:.....::|.|.....|:.|         ..|..|.||||||:||::.|:
Zfish   326 RKAREGKRKDSNSSLFSPLTSYVTAETELKTLITE---------LENAVLVGLHTCGDLASSSLR 381

  Fly   281 VFHAQTDCRLLCNVGCCYHLLRERYSQQEFFGNKSLMELQTD--YGFPLSQYLRERQVRMGRNAR 343
            :|.|:.:.|.:|:||||||||.|.:.|..       ....:|  .|||:||||:::....|||||
Zfish   382 MFRAKQELRAVCSVGCCYHLLSEEFDQDR-------PGCTSDGVCGFPMSQYLKDQACFCGRNAR 439

  Fly   344 MLAAQSIERTLDTKELPNVTLYYRALLEILVCRHAPELKNELQVGKV-RKFESFEEYIQKCATKL 407
            |.|..::||......||..:|:|||:|.:::..|....|:|.:||.| .|..||.:|:::...||
Zfish   440 MSACLALERVSAGGGLPMESLFYRAVLHVILQDHYDCFKSEKRVGNVYSKATSFADYVRRALRKL 504

  Fly   408 DAPWLAAVEKEELQSLLQEYAVHKYFLDLFYLLRMSFAPVLESLILLDRLLYLKEL-GYERSYLI 471
            |.. .:.:...::||....|......:..|.:|:::.||.:|.|||||||.||||. ....:.|:
Zfish   505 DLD-ESKLSDGDIQSYHDRYTPRMNEMVAFNMLKVTLAPCIEGLILLDRLCYLKEQENVSHAALV 568

  Fly   472 DLFDPVISPRHFAIVS 487
            .||||:.|||.:|:|:
Zfish   569 QLFDPLQSPRCYAVVA 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33964	NP_001033941.1	Methyltransf_32	122..304	CDD:379330	68/276 (25%)
mettl25	XP_073802771.1	None