Protein Alignment CG33964 and F25H2.12

DIOPT Version :10

• Sequence 1: NP_001033941.1
• Gene: CG33964 / 3772719
• FlyBaseID: FBgn0053964
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_492768.1
• Gene: F25H2.12 / 172945
• WormBaseID: WBGene00009123
• Length: 478
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 141/547 - (25%)
• Similarity: 230/547 - (42%)
• Gaps: 140/547 - (25%)

  Fly     6 VVQLQRRL---DGLLAFLNPHWDFVNCHMVNYLTDQHWDGFLS-ETLKSEI-----------AGK 55
            ||...||:   ..:..|.:..||         |.:..|..:|: |:|:..|           |..
 Worm     9 VVSKYRRILNSRSIEYFASSSWD---------LLEDEWREYLNLESLEDVIVFVNSSDNLVSADC 64

  Fly    56 EDVALAIED------LFWKTDESERFPA--WREFLGKSKQERLSLHPKLLTSVEELIEGQGNSTQ 112
            ..:..::.|      ||....:....|:  ||::.|.:: :.|:...:.::|...|
 Worm    65 ASIPHSLRDLKANLKLFEYNRKCVENPSDLWRQWTGTTR-DGLNASFRTISSANGL--------- 119

  Fly   113 LSIREFMSAKKCHEVDLTAVLVDQL---VKNSGQDC-FIVDAGDGKGYLSSRLALQYGHRVLGID 173
              :|:.:.|||.||:|....|:.|:   .|:|.... .:||.|.|.|:||..:::.....|:.::
 Worm   120 --VRKRIKAKKQHEIDRIVELISQIQIFQKDSADPIDSLVDIGAGIGHLSRMISIHNNISVMAVE 182

  Fly   174 ANAANTENALNRNRKLQRAWNGLTERAELQVQGITPKRRSKKSPARESTKSAPALENY--KTT-- 234
            .           |::...|.|.|.|:..|                 :|.|....:||:  |:|
 Worm   183 G-----------NQQFTLAANSLDEKLLL-----------------DSAKIGSRIENFNVKSTPI 219

  Fly   235 --AKFITTELNFGALLAENFTQFRPEDSPNICLTGLHTCGNLAATCLQVFHAQTDCRLLCNVGCC 297
              ..|:|.:|   ||..::|.      ..:..|.|||.||:.::|.|:||......:.|...|||
 Worm   220 RYTNFVTEDL---ALKIDDFA------VNSAILVGLHCCGDFSSTILKVFQKSEKSKALVLFGCC 275

  Fly   298 Y-------HLLRERYSQQEFFGNKSLMELQTDYG----FPLSQ---------YLRERQVRMGRNA 342
            |       |.||...::.|    :.:.| .|.:|    ||||:         .|||.......|.
 Worm   276 YHKEFQCFHFLRPENNENE----REISE-NTSFGKSTVFPLSKKWENVEIDYLLREAACHNNENL 335

  Fly   343 RMLAAQSIERTLDTKELPNVTLYYRALLEILVCRHAPELKNELQVG--KVRKFE---SFEEYIQK 402
            .       ||.|  |:..:::.|.|:.||..:.: ..||..:..:|  .|:..|   :|||||:|
 Worm   336 E-------ERFL--KQKIDLSRYARSYLEKWIWK-VSELPEDRNIGMCSVKCIENQTTFEEYIRK 390

  Fly   403 CATK-----LDAPWLAAVEKEELQSLLQEYAVHKYFLDLFYLLRMSFAPVLESLILLDRLLYLKE 462
            ....     ||.. |..:.:.||.:.:......::  |.|.:||..|||.:||.|:.||:..|:|
 Worm   391 AMANRGNHLLDKV-LQIIPQSELSAHVSSLRSSQF--DSFEVLRCMFAPAIESAIIDDRVELLRE 452

  Fly   463 LGYERSYLIDLFDPVISPRHFAIVSIK 489
            .|. .|.::.||:|.||||:.||::.|
 Worm   453 NGI-NSRVVPLFEPSISPRNLAIIAYK 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33964	NP_001033941.1	Methyltransf_32	122..304	CDD:379330	53/198 (27%)
F25H2.12	NP_492768.1	AdoMet_MTases	127..278	CDD:473071	50/187 (27%)