Protein Alignment bbx and Bbx

DIOPT Version :10

• Sequence 1: NP_001027087.1
• Gene: bbx / 3772670
• FlyBaseID: FBgn0024251
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_006522606.1
• Gene: Bbx / 70508
• MGIID: 1917758
• Length: 937
• Species: Mus musculus
• Alignment Length: 643
• Identity: 157/643 - (24%)
• Similarity: 244/643 - (37%)
• Gaps: 194/643 - (30%)

  Fly   206 KLQDCSSDTDDEDDEEEDLDEEEDDEEEAEIQVQLPVQQEVTRIRREAAEEHVDVDVVTVPQQEQ 270
            ||.|.|.: ::||:||||:|           :|||
Mouse    35 KLLDFSEE-EEEDEEEEDID-----------KVQL------------------------------ 57

  Fly   271 DQYSHQVEPRQLQQD--ETADNTRPEHHARRPMNAFLIFCKRHRGIVKERYKTLENRAITKILGD 333
                  :|...|:||  ||.|:..||..|||||||||:||||||.:|::.:..|:||..||||.|
Mouse    58 ------LEADGLEQDVAETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILAD 116

  Fly   334 WWAALDEQEKHCFTDLAQQNKDAFFNANPNFKW-------YKLPAP---PLRTLATRPSNASAGL 388
            |||.||.:||..:||:|::.||||..|||.::|       .|.|.|   |.:.|...|.::|..|
Mouse   117 WWAVLDPKEKQKYTDMAKEYKDAFMKANPGYRWCPTTNKPVKSPTPTVNPRKKLWAFPPDSSRDL 181

  Fly   389 LIPSEDQPQQQVPTSLQVQWAERGEMPRAMLRPNYFKLADETQMGELSSLL-------------- 439
              |:..:.:.:||   |:.                |.:||.||||.||.||
Mouse   182 --PTPKKAKTEVP---QLN----------------FGMADPTQMGGLSMLLLAGEHALGTPEASS 225

  Fly   440 ---------QVQVQEKD--FALQQVLSETSQ-------------FLSAHMPAGNTNGNGNKRSLQ 480
                     ..::::|.  |...::.|.||.             |..|.:.:..:...|.:...:
Mouse   226 GTCRPDISESPELRQKSPLFQFAEISSRTSHPDAPSKQCQASALFQFAEISSSTSQLGGTEPVKR 290

  Fly   481 DNNSSNSSEEEAASGS-----SPNKKVKSSRSCKGKIYQELVNSG-----------------QLA 523
            ..||:.....|....|     ...|.:||..|..|:|  |.:..|                 :.|
Mouse   291 CGNSALFQLAEMCLASEGVKMEDTKLIKSKESDGGRI--EEIEKGKEERGTEVEKTTETSFQKEA 353

  Fly   524 AIAKKSKARLPPAGNMGGNFVDIPLDAGPNTPPVSPPERQGSSPDSMQK--HIRSVSESSSSGFF 586
            ...|.:|..:..:.:: .:...:.:| ......|..|:.....|:..||  |....|.|:||...
Mouse   354 EFGKSAKGNVRESKDL-RDIEQLQMD-NVMAIKVEDPKEIRKEPEDDQKYSHFPDFSYSASSKII 416

  Fly   587 DLEEKIKELPA-------------LSLDAYLQRKRSTKKKKKFSGTKKQRNSNST---------- 628
                 |..:|:             :.....|.:....|||||.:...:..|..||
Mouse   417 -----ISGVPSRKDHMCHPHGIMIIEDPTTLNKPEKIKKKKKKNKLDRHGNDKSTPKKTCKKRQS 476

  Fly   629 SGASATSNVAAADAAAKGAVPLSSEQHVRIKQQQLQAVG----------SQRRKARKESITRRDV 683
            |.:...|.:...:|.|||...:........|:.:..:.|          .::.|::::.:::...
Mouse   477 SESDIESVMYTIEAVAKGDWGVDKLGETPRKKVRPSSSGKGGILDAKPPKKKVKSKEKKVSKEKC 541

  Fly   684 SAIEQEVASILPLTINGSYYFNQSGAPKAVNAPVTSSSASPPLSSNSSSSSSSLSSQA 741
            |.|.:|......|:|:.|         |:|...|.....:.||:....:...||..||
Mouse   542 SDITKESRPPDFLSISAS---------KSVPGEVPEGIKAEPLTPTEDALPPSLPGQA 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bbx	NP_001027087.1	HMG-box_HBP2	298..366	CDD:438805	40/67 (60%)
Bbx	XP_006522606.1	HMG-box_HBP2	81..149	CDD:438805	40/67 (60%)
		DUF2028	190..321	CDD:430742	29/149 (19%)