Protein Alignment bbx and Bbx

DIOPT Version :9

• Sequence 1: NP_001027087.1
• Gene: bbx / 3772670
• FlyBaseID: FBgn0024251
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_006522606.1
• Gene: Bbx / 70508
• MGIID: 1917758
• Length: 937
• Species: Mus musculus
• Alignment Length: 643
• Identity: 157/643 - (24%)
• Similarity: 244/643 - (37%)
• Gaps: 194/643 - (30%)

  Fly   206 KLQDCSSDTDDEDDEEEDLDEEEDDEEEAEIQVQLPVQQEVTRIRREAAEEHVDVDVVTVPQQEQ 270
            ||.|.|.: ::||:||||:|           :|||
Mouse    35 KLLDFSEE-EEEDEEEEDID-----------KVQL------------------------------ 57

  Fly   271 DQYSHQVEPRQLQQD--ETADNTRPEHHARRPMNAFLIFCKRHRGIVKERYKTLENRAITKILGD 333
                  :|...|:||  ||.|:..||..|||||||||:||||||.:|::.:..|:||..||||.|
Mouse    58 ------LEADGLEQDVAETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILAD 116

  Fly   334 WWAALDEQEKHCFTDLAQQNKDAFFNANPNFKW-------YKLPAP---PLRTLATRPSNASAGL 388
            |||.||.:||..:||:|::.||||..|||.::|       .|.|.|   |.:.|...|.::|..|
Mouse   117 WWAVLDPKEKQKYTDMAKEYKDAFMKANPGYRWCPTTNKPVKSPTPTVNPRKKLWAFPPDSSRDL 181

  Fly   389 LIPSEDQPQQQVPTSLQVQWAERGEMPRAMLRPNYFKLADETQMGELSSLL-------------- 439
              |:..:.:.:||   |:.                |.:||.||||.||.||
Mouse   182 --PTPKKAKTEVP---QLN----------------FGMADPTQMGGLSMLLLAGEHALGTPEASS 225

  Fly   440 ---------QVQVQEKD--FALQQVLSETSQ-------------FLSAHMPAGNTNGNGNKRSLQ 480
                     ..::::|.  |...::.|.||.             |..|.:.:..:...|.:...:
Mouse   226 GTCRPDISESPELRQKSPLFQFAEISSRTSHPDAPSKQCQASALFQFAEISSSTSQLGGTEPVKR 290

  Fly   481 DNNSSNSSEEEAASGS-----SPNKKVKSSRSCKGKIYQELVNSG-----------------QLA 523
            ..||:.....|....|     ...|.:||..|..|:|  |.:..|                 :.|
Mouse   291 CGNSALFQLAEMCLASEGVKMEDTKLIKSKESDGGRI--EEIEKGKEERGTEVEKTTETSFQKEA 353

  Fly   524 AIAKKSKARLPPAGNMGGNFVDIPLDAGPNTPPVSPPERQGSSPDSMQK--HIRSVSESSSSGFF 586
            ...|.:|..:..:.:: .:...:.:| ......|..|:.....|:..||  |....|.|:||...
Mouse   354 EFGKSAKGNVRESKDL-RDIEQLQMD-NVMAIKVEDPKEIRKEPEDDQKYSHFPDFSYSASSKII 416

  Fly   587 DLEEKIKELPA-------------LSLDAYLQRKRSTKKKKKFSGTKKQRNSNST---------- 628
                 |..:|:             :.....|.:....|||||.:...:..|..||
Mouse   417 -----ISGVPSRKDHMCHPHGIMIIEDPTTLNKPEKIKKKKKKNKLDRHGNDKSTPKKTCKKRQS 476

  Fly   629 SGASATSNVAAADAAAKGAVPLSSEQHVRIKQQQLQAVG----------SQRRKARKESITRRDV 683
            |.:...|.:...:|.|||...:........|:.:..:.|          .::.|::::.:::...
Mouse   477 SESDIESVMYTIEAVAKGDWGVDKLGETPRKKVRPSSSGKGGILDAKPPKKKVKSKEKKVSKEKC 541

  Fly   684 SAIEQEVASILPLTINGSYYFNQSGAPKAVNAPVTSSSASPPLSSNSSSSSSSLSSQA 741
            |.|.:|......|:|:.|         |:|...|.....:.||:....:...||..||
Mouse   542 SDITKESRPPDFLSISAS---------KSVPGEVPEGIKAEPLTPTEDALPPSLPGQA 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bbx	NP_001027087.1	SOX-TCF_HMG-box	296..367	CDD:238684	42/77 (55%)
Bbx	XP_006522606.1	SOX-TCF_HMG-box	79..150	CDD:238684	41/70 (59%)
		DUF2028	190..>322	CDD:312980	29/150 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842356
Domainoid	1	1.000	97	1.000	Domainoid score	I7286
eggNOG	1	0.900	-	-		E1_KOG2746
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4113
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0009740
OrthoInspector	1	1.000	-	-		oto94530
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13059
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8059
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.010