Protein Alignment bbx and BBX

DIOPT Version :10

• Sequence 1: NP_001027087.1
• Gene: bbx / 3772670
• FlyBaseID: FBgn0024251
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_024309412.1
• Gene: BBX / 56987
• HGNCID: 14422
• Length: 953
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 65/331 - (19%)
• Similarity: 110/331 - (33%)
• Gaps: 110/331 - (33%)

  Fly    37 DLRSIVRKSEEISLDDD---SETEKTLQNDPDFMKS-LDEY------ASEKSKEIIAATVSSEKI 91
            :|..:::|.|::.|:.:   ...:..|...|.|..| |..:      ||.|.|..: .::..:..
Human   257 NLAEMIQKGEQLFLEPELVIPHRQHRLFTAPTFTGSFLSPWPPAVTDASFKVKSHV-YSLEGQDC 320

  Fly    92 KESP---PPAVSSVKKAVNL---TKPVTQSINIQVIRKEDQCQMEKNIKKNAKKSGKKSAKSGNG 150
            |.:|   |.|.:.|.:...|   .|...:||:       |||         |:.....|..|..|
Human   321 KYTPMFGPEARTLVLRLAQLITQAKHTAKSIS-------DQC---------AESPAGHSFLSWLG 369

  Fly   151 EVLVNPGGSNTPHFATPVDVESLWCQEKDPDAKQLPSLLESKLYLQNADVIARKLLEPSFAYSFQ 215
            ...::..||.|.:               |.|.....|:.::..||:.|....|::...|.|...|
Human   370 FSSMDTNGSYTAN---------------DLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQ 419

  Fly   216 FTVDI--------------------NFVLTGI--------VRQCKFTYSG--------------- 237
            ||:.:                    ..:||.:        :|:.:..|.|
Human   420 FTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLRRFEIEYQGDPELQPIRSYEIASL 484

  Fly   238 -RNTFK---SFNYMFKHK---YCESENFQLFYMNHEGRFMEVHDTLTLKQMLIVHGAFPKG---I 292
             |..|:   :.|:.|..:   .|..::|.       |.|...|  ||...:...|...|.|   :
Human   485 VRTLFRLSSAINHRFAGQMAALCSRDDFL-------GSFCRYH--LTEPGLASRHLLSPVGRRQV 540

  Fly   293 YNNLRG 298
            ..:.||
Human   541 AGHTRG 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bbx	NP_001027087.1	HMG-box_HBP2	298..366	CDD:438805	1/1 (100%)
BBX	XP_024309412.1	HMG-box_HBP2	93..161	CDD:438805
		DUF2028	203..334	CDD:430742	17/77 (22%)