Protein Alignment bbx and LEF1

DIOPT Version :9

• Sequence 1: NP_001027087.1
• Gene: bbx / 3772670
• FlyBaseID: FBgn0024251
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_005263103.1
• Gene: LEF1 / 51176
• HGNCID: 6551
• Length: 414
• Species: Homo sapiens
• Alignment Length: 118
• Identity: 34/118 - (28%)
• Similarity: 59/118 - (50%)
• Gaps: 19/118 - (16%)

  Fly   248 RIRREAAEEHVDVDVVTV-PQQEQDQYSHQVEPRQLQQDETADNTRPEHHARRPMNAFLIFCKRH 311
            ::::|  ..|.|.|::.| ||.||.:   :.||:           ||  |.::|:|||:::.|..
Human   267 QVKQE--HPHTDSDLMHVKPQHEQRK---EQEPK-----------RP--HIKKPLNAFMLYMKEM 313

  Fly   312 RGIVKERYKTLENRAITKILGDWWAALDEQEKHCFTDLAQQNKDAFFNANPNF 364
            |..|.......|:.||.:|||..|.||..:|:..:.:||::.:.......|.:
Human   314 RANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bbx	NP_001027087.1	SOX-TCF_HMG-box	296..367	CDD:238684	21/69 (30%)
LEF1	XP_005263103.1	CTNNB1_binding	1..213	CDD:285538
		SOX-TCF_HMG-box	298..369	CDD:238684	21/69 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910