Protein Alignment: mei-218 and mcm6

• Sequence 1: NP_001027068.1
• Gene: mei-218
• FlyBaseID: FBgn0002709
• Length: 1186
• Species: Drosophila melanogaster
• Sequence 2: NP_596614.1
• Gene: mcm6
• PomBaseID: SPBC211.04c
• Length: 892
• Species: Schizosaccharomyces pombe
• Alignment Length: 903
• Identity: 166/904 (18%)
• Similarity: 293/904 (32%)
• Gaps: 301/904 (33%)

  Fly   416 ASVTNNSSAPIRIAPRQQTTQSSGPSVVHNEDEDVMPPTPNQSERRQ-----RRFPRR---NHNP 472
            ||..||:|.|......|.:.....|:|       .||..|..|...:     :|.|..   ...|
pombe     5 ASQGNNASTPAYRYGFQTSEVGDRPTV-------SMPSQPESSAMLEDDGMVKRKPFAAIGEAIP 62

  Fly   473 RMVRSL-QAVSREFTESLLEGSSGKTPEKEVVPYQQQEK--PRQVK--SSPEIHA--------SS 524
            :::.:. ::|...|.|.||..|..:....:.:|...|||  .:|:.  :..|||.        :|
pombe    63 KVIDTTGESVREAFEEFLLSFSDDRVAGGDALPSASQEKYYVQQIHGLAMYEIHTVYVDYKHLTS 127

  Fly   525 HMRKLAMGSVLNSNAKEFHPTGESHLTHKVSRLSQRRCRQRFTRSLHAKKNNPREQLPNPDSAPE 589
            :...||:..|  .....|.|    .|...:.:|.: :....:.||..:::|  ....||..::
pombe   128 YNDVLALAIV--EQYYRFSP----FLLRALQKLIE-KFEPEYYRSSLSREN--ASLSPNFKAS-- 181

  Fly   590 PILEYTSEIDDQPCPPRQTV-DTPIEAIVPPAMI--EVSATGNLPPVF----YFDQQSGIIWSN- 646
               :.|..:.....|.|.|: |...:.|.....|  .|:.|..:.|..    :..::...:.||
pombe   182 ---DKTFALAFYNLPFRSTIRDLRTDRIGRLTTITGTVTRTSEVRPELAQGTFICEECHTVVSNV 243

  Fly   647 ------SSP-QIPVEIQSN------SVSQSVFR---------------LASLP------------ 671
                  :.| |.|.|:.:|      ::|||.|:               ..|:|
pombe   244 EQAFRYTEPTQCPNELCANKRSWRLNISQSSFQDWQKVRIQENSNEIPTGSMPRTLDVILRGDIV 308

  Fly   672 --------C--TGVGTTNMDIFTSSPPPIQHMS-------SSRLPSSISGPTQLSHTLSSPPVEN 719
                    |  ||:.....|:.....|.::..:       ..|....::|       |.|..|.:
pombe   309 ERAKAGDKCAFTGILIAVPDVSQLGIPGVKPEAYRDSRNFGGRDADGVTG-------LKSLGVRD 366

  Fly   720 QHQQHLWESCIHQDEDLMYSRPLLDMDQEETQP-EQQDQEWQWESEIEPPSFQSENQVVADEHGE 783
            ...:..:.:|:.|.:| ...:...|:..:.:|. |:||:           ..||.:|   :|..:
pombe   367 LTYKLSFLACMVQPDD-ANDKSGADVRGDGSQGIEEQDE-----------FLQSLSQ---EEIDD 416

  Fly   784 ENAYLAKDAGPPLERHMIFR-----APSQHGQEYPKPDLNCVPSSIKKLHHLISSQYSDYSFVYA 843
            ..|.:..|       |:..|     |||.:|.|..|
pombe   417 LRAMVHSD-------HIYSRLTNSLAPSVYGHEIIK----------------------------- 445

  Fly   844 LSAQISQDCVPMDCFVYLKMILLASIVSI-----ESDEVRAPISLCIIATDSLMANRLLNKVGQL 903
                              |.|||..:..:     |...:|..:::||:...|...::.|..|...
pombe   446 ------------------KGILLQLMGGVHKLTPEGINLRGDLNICIVGDPSTSKSQFLKYVCNF 492

  Fly   904 APRFLGPHEYGLQPTFNAL--------PTRFNWIVASPLLLAQQGVYYAGDWNRLSKDQGCQLEK 960
            .||.:  :..|...:...|        .|....|.|..|:||..|:....:::::.......:.:
pombe   493 LPRAI--YTSGKASSAAGLTAAVVKDEETGDFTIEAGALMLADNGICAIDEFDKMDLSDQVAIHE 555

  Fly   961 CIENGAVPVPQLHIDQPLKAAVWTYWQPNNSTNQTLALAKLCPIFGLPIYMGAQASNSLWNSIIQ 1025
            .:|...:.:.:..|...|.|             :|..||...||.|
pombe   556 AMEQQTISIAKAGIQATLNA-------------RTSILAAANPIGG------------------- 588

  Fly  1026 KHNAEGQIVVNDGLSIP-----------------EDDMRMLIHL--LHQRKTTLTDGAQ------ 1065
            ::|.:..:..|..:|.|                 ..|..:..|:  :|:    |.|.|.
pombe   589 RYNRKTTLRNNINMSAPIMSRFDLFFVVLDECNESVDRHLAKHIVDIHR----LRDDAMQPEFST 649

  Fly  1066 HMLQKYYVISRKERPNVFSS------KTYIVLKQL----AECFAKLALRLEV--LESDVCVAIFH 1118
            ..||:|...:|..:|.:.:.      |.|   |||    |:...|.:.|:.|  |||.:
pombe   650 EQLQRYIRYARTFKPKLNTESCAEIVKKY---KQLRMDDAQGAGKNSYRITVRQLESMI------ 705

  Fly  1119 CEHFVQGIFGAKENQAPPAVFNFNVISCIDP-YMNKFTRWLLQYLNSYEDEELGMHAD 1175
                          :...|:...|.:..|.| ::|:....|.|.:...|.:::.:..|
pombe   706 --------------RLSEAIARANCVDDITPAFVNEAYSLLRQSIIHVERDDIEVEED 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-218	NP_001027068.1	PTZ00112	122..>417	CDD:240274	1/1 (100%)
		MCM	<1023..1116	CDD:278895	27/130 (21%)
mcm6	NP_596614.1	MCM_N	75..209	CDD:291233	32/148 (22%)
		MCM	194..737	CDD:214631	119/680 (18%)
		P-loop_NTPase	<527..616	CDD:304359	18/121 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11630
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100